Obesity but not overweight increases the incidence and mortality of leukemia in adults: A meta-analysis of prospective cohort studies

Leukemia Research

Volumn 36, Issue 7, 2012, Pages 868-875

  Castillo, Jorge J ^a   Reagan, John L ^a   Ingham, Randall R ^a   Furman, Michael ^a   Dalia, Samir ^a   Merhi, Basma ^a   Nemr, Saed ^a   Zarrabi, Ali ^a   Mitri, Joanna ^b  

^a BROWN UNIVERSITY   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Body mass index; Incidence; Leukemia; Meta analysis; Mortality; Obesity; Risk

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; BODY MASS; CANCER INCIDENCE; CANCER MORTALITY; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; COHORT ANALYSIS; DISEASE ASSOCIATION; GENDER; HUMAN; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SYSTEMATIC REVIEW;

ADULT; ALGORITHMS; COHORT STUDIES; FEMALE; HUMANS; INCIDENCE; LEUKEMIA; MALE; OBESITY; OVERWEIGHT; PROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 84862331330     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.12.020     Document Type: Article

References (46)

1. Surveillance, epidemiology and end results [website] 2011, Available at http://seer.cancer.gov/statfacts/index.html [accessed on July 31, 2011].
2. Chang E.T., Hjalgrim H., Smedby K.E., et al. Body mass index and risk of malignant lymphoma in Scandinavian men and women. J Natl Cancer Inst 2005, 97:210-218.
3. Kasim K., Johnson K.C., Levallois P., et al. Recreational physical activity and the risk of adult leukemia in Canada. Cancer Causes Control 2009, 20:1377-1386.
4. Willett E.V., Morton L.M., Hartge P., et al. Non-Hodgkin lymphoma and obesity: a pooled analysis from the InterLymph Consortium. Int J Cancer 2008, 122:2062-2070.
5. Centers for Disease Control and Prevention Overweight and obesity [website] 2011, Available at http://www.cdc.gov/obesity/defining.html [accessed on August 1, 2011].
6. World Health Organization Obesity and overweight [website] 2011, Available at http://www.who.int/mediacentre/factsheets/fs311/en/index.html [accessed on August 1, 2011].
7. Flegal K.M., Carroll M.D., Ogden C.L., et al. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010, 303:235-241.
8. Stroup D.F., Berlin J.A., Morton S.C., et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000, 283:2008-2012.
9. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses [website] 2011, Available at http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp [accessed on July 31, 2011].
10. DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7:177-188.
11. Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. Stat Med 2002, 21:1539-1558.
12. Duval S., Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000, 56:455-463.
13. Britton J.A., Khan A.E., Rohrmann S., et al. Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Haematologica 2008, 93:1666-1677.
14. De Roos A.J., Ulrich C.M., Ray R.M., et al. Intentional weight loss and risk of lymphohematopoietic cancers. Cancer Causes Control 2010, 21:223-236.
15. Engeland A., Tretli S., Hansen S., et al. Height and body mass index and risk of lymphohematopoietic malignancies in two million Norwegian men and women. Am J Epidemiol 2007, 165:44-52.
16. Fernberg P., Odenbro A., Bellocco R., et al. Tobacco use, body mass index, and the risk of leukemia and multiple myeloma: a nationwide cohort study in Sweden. Cancer Res 2007, 67:5983-5986.
17. Lu Y., Prescott J., Sullivan-Halley J., et al. Body size, recreational physical activity, and B-cell non-Hodgkin lymphoma risk among women in the California teachers study. Am J Epidemiol 2009, 170:1231-1240.
18. Moller H., Mellemgaard A., Lindvig K., et al. Obesity and cancer risk: a Danish record-linkage study. Eur J Cancer 1994, 30A:344-350.
19. Oh S.W., Yoon Y.S., Shin S.A. Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study. J Clin Oncol 2005, 23:4742-4754.
20. Pylypchuk R.D., Schouten L.J., Goldbohm R.A., et al. Body mass index, height, and risk of lymphatic malignancies: a prospective cohort study. Am J Epidemiol 2009, 170:297-307.
21. Reeves G.K., Pirie K., Beral V., et al. Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study. BMJ 2007, 335:1134.
22. Ross J.A., Parker E., Blair C.K., et al. Body mass index and risk of leukemia in older women. Cancer Epidemiol Biomarkers Prev 2004, 13:1810-1813.
23. Samanic C., Chow W.H., Gridley G., et al. Relation of body mass index to cancer risk in 362,552 Swedish men. Cancer Causes Control 2006, 17:901-909.
24. Samanic C., Gridley G., Chow W.H., et al. Obesity and cancer risk among white and black United States veterans. Cancer Causes Control 2004, 15:35-43.
25. Soderberg K.C., Kaprio J., Verkasalo P.K., et al. Overweight, obesity and risk of haematological malignancies: a cohort study of Swedish and Finnish twins. Eur J Cancer 2009, 45:1232-1238.
26. Song Y.M., Sung J., Ha M. Obesity and risk of cancer in postmenopausal Korean women. J Clin Oncol 2008, 26:3395-3402.
27. Tsai H.T., Cross A.J., Graubard B.I., et al. Dietary factors and risk of chronic lymphocytic leukemia and small lymphocytic lymphoma: a pooled analysis of two prospective studies. Cancer Epidemiol Biomarkers Prev 2010, 19:2680-2684.
28. Wolk A., Gridley G., Svensson M., et al. A prospective study of obesity and cancer risk (Sweden). Cancer Causes Control 2001, 12:13-21.
29. Batty G.D., Shipley M.J., Jarrett R.J., et al. Obesity and overweight in relation to organ-specific cancer mortality in London (UK): findings from the original Whitehall study. Int J Obes (Lond) 2005, 29:1267-1274.
30. Calle E.E., Rodriguez C., Walker-Thurmond K., et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003, 348:1625-1638.
31. Chiu B.C., Gapstur S.M., Greenland P., et al. Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer. Cancer Epidemiol Biomarkers Prev 2006, 15:2348-2354.
32. Chu D.M., Wahlqvist M.L., Lee M.S., et al. Central obesity predicts non-Hodgkin's lymphoma mortality and overall obesity predicts leukemia mortality in adult Taiwanese. J Am Coll Nutr 2011, 30:310-319.
33. Parr C.L., Batty G.D., Lam T.H., et al. Body-mass index and cancer mortality in the Asia-Pacific Cohort Studies Collaboration: pooled analyses of 424,519 participants. Lancet Oncol 2010, 11:741-752.
34. Larsson S.C., Wolk A. Overweight and obesity and incidence of leukemia: a meta-analysis of cohort studies. Int J Cancer 2008, 122:1418-1421.
35. Renehan A.G., Tyson M., Egger M., et al. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008, 371:569-578.
36. Sant M., Allemani C., Teranu C., et al. Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project. Blood 2010, 116:3724-3734.
37. Gillum R.F., Sempos C.T. Ethnic variation in validity of classification of overweight and obesity using self-reported weight and height in American women and men: the Third National Health and Nutrition Examination Survey. Nutr J 2005, 4:27.
38. Robinson W.S. Ecological correlations and the behavior of individuals. Am Sociol Rev 1950, 15:351-357.
39. Idrovo A.J. Three criteria for ecological fallacy. Environ Health Perspect 2011, 119:A332.
40. Subramanian S.V., Jones K., Kaddour A., et al. Revisiting Robinson: the perils of individualistic and ecologic fallacy. Int J Epidemiol 2009, 38:342-360.
41. Harvey A.E., Lashinger L.M., Hursting S.D. The growing challenge of obesity and cancer: an inflammatory issue. Ann N Y Acad Sci 2010, 1229:45-52.
42. Meijer K., de Vries M., Al-Lahham S., Bruinenberg M., Weening D., Dijkstra M., et al. Human primary adipocytes exhibit immune cell function: adipocytes prime inflammation independent of macrophages. PLoS One 2011, 16:e17154.
43. Donohoe C.L., Doyle S.L., Reynolds J.V. Visceral adiposity, insulin resistance and cancer risk. Diabetol Metab Syndr 2011, 3:12.
44. Gainsford T., Willson T.A., Metcalf D., et al. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci U S A 1996, 93:14564-14568.
45. Caers J., Deleu S., Belaid Z., De Raeve H., Van Valckenborgh E., De Bruyne E., et al. Neighboring adipocytes participate in the bone marrow microenvironment of multiple myeloma cells. Leukemia 2007, 21:1580-1584.
46. Askmyr M., Quach J., Purton L.E. Effects of the bone marrow microenvironment on hematopoietic malignancy. Bone 2011, 48:115-120.