-
1
-
-
57849163103
-
Oxygen sensors at the crossroad of metabolism
-
Aragonés J., Fraisl P., Baes M., Carmeliet P., Oxygen sensors at the crossroad of metabolism Cell Metabolism 2009 9 1 11 22
-
(2009)
Cell Metabolism
, vol.9
, Issue.1
, pp. 11-22
-
-
Aragonés, J.1
Fraisl, P.2
Baes, M.3
Carmeliet, P.4
-
2
-
-
22244440847
-
Proline hydroxylation and gene expression
-
Kaelin W. G., Proline hydroxylation and gene expression Annual Review of Biochemistry 2005 74 115 128
-
(2005)
Annual Review of Biochemistry
, vol.74
, pp. 115-128
-
-
Kaelin, W.G.1
-
3
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
DOI 10.1016/j.molcel.2008.04.009, PII S109727650800292X
-
Kaelin W. G. Jr., Ratcliffe P. J., Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway Molecular Cell 2008 30 4 393 402 (Pubitemid 351681994)
-
(2008)
Molecular Cell
, vol.30
, Issue.4
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
4
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
DOI 10.1016/S0092-8674(01)00507-4
-
Epstein A. C. R., Gleadle J. M., McNeill L. A., Hewitson K. S., O'Rourke J., Mole D. R., Mukherji M., Metzen E., Wilson M. I., Dhanda A., Tian Y. M., Masson N., Hamilton D. L., Jaakkola P., Barstead R., Hodgkin J., Maxwell P. H., Pugh C. W., Schofield C. J., Ratcliffe P. J., C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell 2001 107 1 43 54 (Pubitemid 32972036)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.-M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
5
-
-
72449166462
-
Two distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans
-
Shao Z., Zhang Y., Powell-Coffman J. A., Two distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans Genetics 2009 183 3 821 829
-
(2009)
Genetics
, vol.183
, Issue.3
, pp. 821-829
-
-
Shao, Z.1
Zhang, Y.2
Powell-Coffman, J.A.3
-
6
-
-
27844472745
-
Reversion of lethality and growth defects in Fatiga oxygen-sensor mutant flies by loss of Hypoxia-Inducible Factor-α/Sima
-
DOI 10.1038/sj.embor.7400528, PII 7400528
-
Centanin L., Ratcliffe P. J., Wappner P., Reversion of lethality and growth defects in Fatiga oxygen-sensor mutant flies by loss of Hypoxia-Inducible Factor- /Sima EMBO Reports 2005 6 11 1070 1075 (Pubitemid 41637653)
-
(2005)
EMBO Reports
, vol.6
, Issue.11
, pp. 1070-1075
-
-
Centanin, L.1
Ratcliffe, P.J.2
Wappner, P.3
-
7
-
-
33750976389
-
Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2
-
DOI 10.1128/MCB.00425-06
-
Takeda K., Ho V. C., Takeda H., Duan L. J., Nagy A., Fong G. H., Placental but not heart defects are associated with elevated hypoxia-inducible factor levels in mice lacking prolyl hydroxylase domain protein 2 Molecular and Cellular Biology 2006 26 22 8336 8346 (Pubitemid 44748568)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.22
, pp. 8336-8346
-
-
Takeda, K.1
Ho, V.C.2
Takeda, H.3
Duan, L.-J.4
Nagy, A.5
Fong, G.-H.6
-
8
-
-
79953644844
-
Prolyl hydroxylase domain protein 2 (PHD2) mediates oxygen-induced retinopathy in neonatal mice
-
Duan L.-J., Takeda K., Fong G.-H., Prolyl hydroxylase domain protein 2 (PHD2) mediates oxygen-induced retinopathy in neonatal mice American Journal of Pathology 2011 178 4 1881 1890
-
(2011)
American Journal of Pathology
, vol.178
, Issue.4
, pp. 1881-1890
-
-
Duan, L.-J.1
Takeda, K.2
Fong, G.-H.3
-
9
-
-
34547905406
-
Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system
-
DOI 10.1161/CIRCULATIONAHA.107.701516, PII 0000301720070814000016
-
Takeda K., Cowan A., Fong G. H., Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system Circulation 2007 116 7 774 781 (Pubitemid 47255995)
-
(2007)
Circulation
, vol.116
, Issue.7
, pp. 774-781
-
-
Takeda, K.1
Cowan, A.2
Fong, G.-H.3
-
10
-
-
77954837178
-
Reactivation of hepatic EPO synthesis in mice after PHD loss
-
Minamishima Y. A., Kaelin W. G. Jr., Reactivation of hepatic EPO synthesis in mice after PHD loss Science 2010 329 5990 407
-
(2010)
Science
, vol.329
, Issue.5990
, pp. 407
-
-
Minamishima, Y.A.1
Kaelin Jr., W.G.2
-
11
-
-
42449163874
-
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
-
Minamishima Y. A., Moslehi J., Bardeesy N., Cullen D., Bronson R. T., Kaelin W. G., Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure Blood 2008 111 6 3236 3244
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3236-3244
-
-
Minamishima, Y.A.1
Moslehi, J.2
Bardeesy, N.3
Cullen, D.4
Bronson, R.T.5
Kaelin, W.G.6
-
12
-
-
40949090791
-
Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
-
Takeda K., Aguila H. L., Parikh N. S., Li X., Lamothe K., Duan L. J., Takeda H., Lee F. S., Fong G. H., Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins Blood 2008 111 6 3229 3235
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3229-3235
-
-
Takeda, K.1
Aguila, H.L.2
Parikh, N.S.3
Li, X.4
Lamothe, K.5
Duan, L.J.6
Takeda, H.7
Lee, F.S.8
Fong, G.H.9
-
13
-
-
70350456693
-
A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo
-
Minamishima Y. A., Moslehi J., Padera R. F., Bronson R. T., Liao R., Kaelin W. G. Jr., A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo Molecular and Cellular Biology 2009 29 21 5729 5741
-
(2009)
Molecular and Cellular Biology
, vol.29
, Issue.21
, pp. 5729-5741
-
-
Minamishima, Y.A.1
Moslehi, J.2
Padera, R.F.3
Bronson, R.T.4
Liao, R.5
Kaelin Jr., W.G.6
-
14
-
-
77957254118
-
Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy
-
Moslehi J., Minamishima Y. A., Shi J., Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy Circulation 2010 122 1004 1016
-
(2010)
Circulation
, vol.122
, pp. 1004-1016
-
-
Moslehi, J.1
Minamishima, Y.A.2
Shi, J.3
-
15
-
-
33847095500
-
Isolation of Xenopus HIF-prolyl 4-hydroxylase and rescue of a small-eye phenotype caused by Siah2 over-expression
-
DOI 10.1016/j.bbrc.2007.01.166, PII S0006291X07002446
-
Imaoka S., Muraguchi T., Kinoshita T., Isolation of Xenopus HIF-prolyl 4-hydroxylase and rescue of a small-eye phenotype caused by Siah2 over-expression Biochemical and Biophysical Research Communications 2007 355 2 419 425 (Pubitemid 46282644)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.355
, Issue.2
, pp. 419-425
-
-
Imaoka, S.1
Muraguchi, T.2
Kinoshita, T.3
-
17
-
-
0026285616
-
In situ hybridization: An improved whole-mount method for Xenopus embryos
-
Harland R. M., In situ hybridization: an improved whole-mount method for Xenopus embryos Methods in Cell Biology 1991 36 685 695
-
(1991)
Methods in Cell Biology
, vol.36
, pp. 685-695
-
-
Harland, R.M.1
-
19
-
-
67650634987
-
Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia
-
Van Rooijen E., Voest E. E., Logister I., Korving J., Schwerte T., Schulte-Merker S., Giles R. H., Van Eeden F. J., Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia Blood 2009 113 25 6449 6460
-
(2009)
Blood
, vol.113
, Issue.25
, pp. 6449-6460
-
-
Van Rooijen, E.1
Voest, E.E.2
Logister, I.3
Korving, J.4
Schwerte, T.5
Schulte-Merker, S.6
Giles, R.H.7
Van Eeden, F.J.8
-
20
-
-
0036433394
-
Mammalian EGLN genes have distinct patterns of mRNA expression and regulation
-
Lieb M. E., Menzies K., Moschella M. C., Ni R., Taubman M. B., Mammalian EGLN genes have distinct patterns of mRNA expression and regulation Biochemistry and Cell Biology 2002 80 4 421 426 (Pubitemid 35365999)
-
(2002)
Biochemistry and Cell Biology
, vol.80
, Issue.4
, pp. 421-426
-
-
Lieb, M.E.1
Menzies, K.2
Moschella, M.C.3
Ni, R.4
Taubman, M.B.5
|