Cellular and humoral mechanisms involved in the control of tuberculosis

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Zuiga, Joaquin ^a   Torres García, Diana ^a   Santos Mendoza, Teresa ^a   Rodriguez Reyna, Tatiana S ^b   Granados, Julio ^b   Yunis, Edmond J ^c  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; CERTOLIZUMAB PEGOL; ETANERCEPT; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GOLIMUMAB; IMMUNOGLOBULIN G1 ANTIBODY; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PERFORIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; VIMENTIN;

ADAPTIVE IMMUNITY; ANTIBODY RESPONSE; APOPTOSIS; AUTOIMMUNE DISEASE; AUTOPHAGY; BACTERIAL CELL WALL; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOLOGICAL THERAPY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MIGRATION; CELLULAR IMMUNITY; CROHN DISEASE; DENDRITIC CELL; EXTRAPULMONARY TUBERCULOSIS; HOST PATHOGEN INTERACTION; HUMAN; HUMORAL IMMUNITY; IMMUNE DYSREGULATION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOCOMPETENT CELL; IMMUNOPATHOGENESIS; INFECTION; INFECTION CONTROL; INFLAMMATION; INFLAMMATORY DISEASE; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MEMORY T LYMPHOCYTE; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PHAGOSOME; PRIORITY JOURNAL; PROPHYLAXIS; PSORIASIS; REVIEW; RHEUMATOID ARTHRITIS; RISK FACTOR; SPONDYLOARTHROPATHY; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TH1 CELL; TH2 CELL; TREATMENT FAILURE; TUBERCULOID LEPROSY; TUBERCULOSIS;

EID: 84862293544     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/193923     Document Type: Review

References (205)

1. Sakula A., Robert Koch: centenary of the discovery of the tubercle bacillus, 1882 Thorax 1982 37 4 246 251 (Pubitemid 12108474)
2. Ligon B. L., Robert Koch: nobel laureate and controversial figure in tuberculin research Seminars in Pediatric Infectious Diseases 2002 13 4 289 299
3. Smith K. C., Armitige L., Wanger A., A review of tubercolosis: reflections on the past, present and future of a global epidemic disease Expert Review of Anti-Infective Therapy 2003 1 3 483 491 (Pubitemid 38855112)
4. World Health Organization, Global Tuberculosis Control: WHO Report 2011 2011 Geneva, Switzerland World Health Organization. WHO/HTM/TB/2011.16
5. Ahmad S., Pathogenesis, immunology, and diagnosis of latent Mycobacterium tuberculosis infection Clinical and Developmental Immunology 2011 2011 17
6. Ahmad S., New approaches in the diagnosis and treatment of latent tuberculosis infection Respiratory Research 2010 11, article 169
7. Ralph A. P., Kelly P. M., Anstey N. M., L-arginine and vitamin D: novel adjunctive immunotherapies in tuberculosis Trends in Microbiology 2008 16 7 336 344
8. Nathan C., Role of iNOS in human host defense Science 2006 312 5782 1874 1875
9. Cooper A. M., Adams L. B., Dalton D. K., Appelberg R., Ehlers S., IFN- and NO in mycobacterial disease: new jobs for old hands Trends in Microbiology 2002 10 5 221 226 (Pubitemid 34327814)
10. Beham A. W., Puellmann K., Laird R., A TNF-regulated recombinatorial macrophage immune receptor implicated in granuloma formation in tuberculosis PLoS Pathogens 2011 7 11
11. Szereday L., Baliko Z., Szekeres-Bartho J., / T cell subsets in patients with active Mycobacterium tuberculosis infection and tuberculin anergy Clinical and Experimental Immunology 2003 131 2 287 291 (Pubitemid 36205141)
12. Peng M. Y., Wang Z. H., Yao C. Y., Jiang L., Jin Q., Wang J., Li B., Interleukin 17-producing T cells increased in patients with active pulmonary tuberculosis Cellular and Molecular Immunology 2008 5 3 203 208
13. Bloom B. R., Bloom B. R., Pathogenesis of pulmonary tuberculosis An Interplay between Tissue-Damaging and Macrophage-Activating Immune Responses: Dual Mechanisms That Control Bacillary Multiplication 1994 Washington, DC, USA American Society for Microbiology 459 484
14. Lurie M. B., Resistance to Tuberculosis: Experimental Studies in Native and Acquired Defensive Mechanisms 1964 Harvard University Press
15. Kaufmann S. H. E., How can immunology contribute to the control of tuberculosis? Nature Reviews Immunology 2001 1 1 20 30 (Pubitemid 33741972)
16. Schaible U. E., Sturgill-Koszycki S., Schlesinger P. H., Russell D. G., Cytokine activation leads to acidification and increases maturation of Mycobacterium avium -containing phagosomes in murine macrophages Journal of Immunology 1998 160 3 1290 1296 (Pubitemid 28093427)
17. Fenhalls G., Stevens L., Bezuidenhout J., Amphlett G. E., Duncan K., Bardin P., Lukey P. T., Distribution of IFN-, IL-4 and TNF- protein and CD8 T cells producing IL-12p40 mRNA in human lung tuberculous granulomas Immunology 2002 105 3 325 335 (Pubitemid 34304409)
18. Herrera M. T., Torres M., Nevels D., Perez-Redondo C. N., Ellner J. J., Sada E., Schwander S. K., Compartmentalized bronchoalveolar IFN- and IL-12 response in human pulmonary tuberculosis Tuberculosis 2009 89 1 38 47
19. Schierloh P., Yokobori N., Alemn M., Musella R. M., Beigier-Bompadre M., Saab M. A., Alves L., Abbate E., de la Barrera S. S., Sasiain M. C., Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the enrichment of IFN- -producing CD56bright cells in tuberculous pleurisy Journal of Immunology 2005 175 10 6852 6860 (Pubitemid 41598930)
20. Sadek M. I., Sada E., Toossi Z., Schwander S. K., Rich E. A., Chemokines induced by infection of mononuclear phagocytes with mycobacteria and present in lung alveoli during active pulmonary tuberculosis American Journal of Respiratory Cell and Molecular Biology 1998 19 3 513 521 (Pubitemid 128354222)
21. Blomgran R., Ernst J. D., Lung neutrophils facilitate activation of naive antigen-specific CD4 + T cells during Mycobacterium tuberculosis infection Journal of Immunology 2011 186 12 7110 7119
22. Takeda K., Akira S., Toll-like receptors in innate immunity International Immunology 2005 17 1 1 14
23. Saunders B. M., Britton W. J., Life and death in the granuloma: immunopathology of tuberculosis Immunology and Cell Biology 2007 85 2 103 111 (Pubitemid 46398725)
24. Saunders B. M., Frank A. A., Orme I. M., Cooper A. M., CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis Cellular Immunology 2002 216 1-2 65 72 (Pubitemid 35193446)
25. Tsai M. C., Chakravarty S., Zhu G., Xu J., Tanaka K., Koch C., Tufariello J., Flynn J., Chan J., Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension Cellular Microbiology 2006 8 2 218 232 (Pubitemid 43356045)
26. Khader S. A., Bell G. K., Pearl J. E., Fountain J. J., Rangel-Moreno J., Cilley G. E., Shen F., Eaton S. M., Gaffen S. L., Swain S. L., Locksley R. M., Haynes L., Randall T. D., Cooper A. M., IL-23 and IL-17 in the establishment of protective pulmonary CD4 + T cell responses after vaccination and during Mycobacterium tuberculosis challenge Nature Immunology 2007 8 4 369 377 (Pubitemid 46745412)
27. Yoshida Y. O., Umemura M., Yahagi A., O'Brien R. L., Ikuta K., Kishihara K., Hara H., Nakae S., Iwakura Y., Matsuzaki G., Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung Journal of Immunology 2010 184 8 4414 4422
28. Peters W., Ernst J. D., Mechanisms of cell recruitment in the immune response to Mycobacterium tuberculosis Microbes and Infection 2003 5 2 151 158 (Pubitemid 36316057)
29. Cardona P. J., A dynamic reinfection hypothesis of latent tuberculosis infection Infection 2009 37 2 80 86
30. van Crevel R., Ottenhoff T. H. M., van der Meer J. W. M., Innate immunity to Mycobacterium tuberculosis Clinical Microbiology Reviews 2002 15 2 294 309 (Pubitemid 34303767)
31. Mishra A. K., Driessen N. N., Appelmelk B. J., Besra G. S., Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction FEMS Microbiology Reviews 2011 35 6 1126 1157
32. Cao B., White J. M., Williams S. J., Synthesis of glycoconjugate fragments of mycobacterial phosphatidylinositol mannosides and lipomannan Beilstein Journal of Organic Chemistry 2011 7 369 377
33. Constantoulakis P., Filiou E., Rovina N., Chras G., Hamhougia A., Karabela S., Sotiriou A., Roussos C., Poulakis N., In vivo expression of innate immunity markers in patients with Mycobacterium tuberculosis infection BMC Infectious Diseases 2010 10, article 243 1 10
34. Marakalala M. J., Graham L. M., Brown G. D., The role of Syk/CARD9-coupled C-type lectin receptors in immunity to Mycobacterium tuberculosis infections Clinical and Developmental Immunology 2010 2010 9
35. Leber J. H., Crimmins G. T., Raghavan S., Meyer-Morse N. P., Cox J. S., Portnoy D. A., Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen PLoS Pathogens 2008 4 1 84 95
36. Court N., Vasseur V., Vacher R., Fremond C., Shebzukhov Y., Yeremeev V. V., Maillet I., Nedospasov S. A., Gordon S., Fallon P. G., Suzuki H., Ryffel B., Quesniaux V. F. J., Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection Journal of Immunology 2010 184 12 7057 7070
37. Carvalho N. B., Oliveira F. S., Dures F. V., de Almeida L. A., Florido M., Prata L. O., Caliari M. V., Appelberg R., Oliveira S. C., Toll-like receptor 9 is required for full host resistance to Mycobacterium avium infection but plays no role in induction of Th1 responses Infection and Immunity 2011 79 4 1638 1646
38. Bafica A., Scanga C. A., Feng C. G., Leifer C., Cheever A., Sher A., TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis Journal of Experimental Medicine 2005 202 12 1715 1724 (Pubitemid 41815877)
39. Chow J. C., Young D. W., Golenbock D. T., Christ W. J., Gusovsky F., Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction The Journal of Biological Chemistry 1999 274 16 10689 10692
40. Chen Y. C., Hsiao C. C., Chen C. J., Chin C. H., Liu S. F., Wu C. C., Eng H. L., Chao T. Y., Tsen C. C., Wang Y. H., Lin M. C., Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts BMC Medical Genetics 2010 11 1, article 17 1 10
41. Kleinnijenhuis J., Oosting M., Joosten L. A. B., Netea M. G., van Crevel R., Innate immune recognition of Mycobacterium tuberculosis Clinical and Developmental Immunology 2011 2011 12
42. Noss E. H., Pai R. K., Sellati T. J., Radolf J. D., Belisle J., Golenbock D. T., Boom W. H., Harding C. V., Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis Journal of Immunology 2001 167 2 910 918 (Pubitemid 32660847)
43. Ogus A. C., Yoldas B., Ozdemir T., Uguz A., Olcen S., Kaser I., Coskun M., Cilli A., Yegin O., The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease European Respiratory Journal 2004 23 2 219 223 (Pubitemid 38195506)
44. McBride A., Bhatt K., Salgame P., Development of a secondary immune response to Mycobacterium tuberculosis is independent of Toll-like receptor 2 Infection and Immunity 2011 79 3 1118 1123
45. Reiling N., Holscher C., Fehrenbach A., Kroger S., Kirschning C. J., Goyert S., Ehlers S., Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis Journal of Immunology 2002 169 7 3480 3484
46. Sugawara I., Yamada H., Li C., Mizuno S., Takeuchi O., Akira S., Mycobacterial infection in TLR2 and TLR6 knockout mice Microbiology and Immunology 2003 47 5 327 336 (Pubitemid 36604618)
47. Poltorak A., He X., Smirnova I., Liu M. Y., van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B., Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 1998 282 5396 2085 2088 (Pubitemid 29001265)
48. Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S., Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product Journal of Immunology 1999 162 7 3749 3752 (Pubitemid 29314747)
49. Means T. K., Jones B. W., Schromm A. B., Shurtleff B. A., Smith J. A., Keane J., Golenbock D. T., Vogel S. N., Fenton M. J., Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis -induced macrophage responses Journal of Immunology 2001 166 6 4074 4082 (Pubitemid 32224938)
50. Abel B., Thieblemont N., Quesniaux V. J. F., Brown N., Mpagi J., Miyake K., Bihl F., Ryffel B., Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice Journal of Immunology 2002 169 6 3155 3162 (Pubitemid 35013161)
51. Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., Akira S., A Toll-like receptor recognizes bacterial DNA Nature 2000 408 6813 740 745 (Pubitemid 32015992)
52. Fremond C. M., Yeremeev V., Nicolle D. M., Jacobs M., Quesniaux V. F., Ryffel B., Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88 The Journal of Clinical Investigation 2004 114 12 1790 1799 (Pubitemid 40385535)
53. Scanga C. A., Bafica A., Feng C. G., Cheever A. W., Hieny S., Sher A., MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression Infection and Immunity 2004 72 4 2400 2404 (Pubitemid 38419959)
54. Watters T. M., Kenny E. F., O'Neill L. A. J., Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins Immunology and Cell Biology 2007 85 6 411 419 (Pubitemid 47367505)
55. Seki E., Tsutsui H., Tsuji N. M., Hayashi N., Adachi K., Nakano H., Futatsugi-Yumikura S., Takeuchi O., Hoshino K., Akira S., Fujimoto J., Nakanishi K., Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice Journal of Immunology 2002 169 7 3863 3868
56. Hlscher C., Reiling N., Schaible U. E., Holscher A., Bathmann C., Korbel D., Lenz I., Sonntag T., Kroger S., Akira S., Mossmann H., Kirschning C. J., Wagner H., Freudenberg M., Ehlers S., Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9 European Journal of Immunology 2008 38 3 680 694
57. Takeuchi O., Hoshino K., Akira S., Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection Journal of Immunology 2000 165 10 5392 5396
58. Feng C. G., Scanga C. A., Collazo-Custodio C. M., Cheever A. W., Hieny S., Caspar P., Sher A., Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals Journal of Immunology 2003 171 9 4758 4764 (Pubitemid 37310594)
59. Chatterjee S., Dwivedi V. P., Singh Y., Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a Toll-like receptor-2-dependent manner PLoS Pathogens 2011 7 11 1 12
60. Stokes C. A., Ismail S., Dick E. P., Bennett J. A., Johnston S. L., Edwards M. R., Sabroe I., Parker L. C., Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection Journal of Virology 2011 85 15 7912 7921
61. Couillin I., Vasseur V., Charron S., Gasse P., Tavernier M., Guillet J., Lagente V., Fick L., Jacobs M., Coelho F. R., Moser R., Ryffel B., IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema Journal of Immunology 2009 183 12 8195 8202
62. Lousberg E. L., Diener K. R., Fraser C. K., Phipps S., Foster P. S., Chen W., Uematsu S., Akira S., Robertson S. A., Brown M. P., Hayball J. D., Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of Toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition Journal of Virology 2011 85 7 3385 3396
63. Schneider B. E., Korbel D., Hagens K., Koch M., Raupach B., Enders J., Kaufmann S. H. E., Mittrucker H. W., Schaible U. E., A role for IL-18 in protective immunity against Mycobacterium tuberculosis European Journal of Immunology 2010 40 2 396 405
64. Philips J. A., Ernst J. D., Tuberculosis pathogenesis and immunity Annual Review Pathology 2011 7 353 384
65. Bacon K., Baggiolini M., Broxmeyer H., Chemokine/chemokine receptor nomenclature Journal of Interferon and Cytokine Research 2002 22 10 1067 1068
66. Mayanja-Kizza H., Wajja A., Wu M., Peters P., Nalugwa G., Mubiru F., Aung H., Vanham G., Hirsch C., Whalen C., Ellner J., Toossi Z., Activation of -chemokines and CCR5 in persons infected with human immunodeficiency virus type 1 and tuberculosis The Journal of Infectious Diseases 2001 183 12 1801 1804 (Pubitemid 32523244)
67. Algood H. M. S., Chan J., Flynn J. L., Chemokines and tuberculosis Cytokine and Growth Factor Reviews 2003 14 6 467 477 (Pubitemid 37296020)
68. Serbina N. V., Jia T., Hohl T. M., Pamer E. G., Monocyte-mediated defense against microbial pathogens Annual Review of Immunology 2008 26 421 452 (Pubitemid 351600381)
69. Gonzalez-Juarrero M., Shim T. S., Kipnis A., Junqueira-Kipnis A. P., Orme I. M., Dynamics of macrophage cell populations during murine pulmonary tuberculosis Journal of Immunology 2003 171 6 3128 3135 (Pubitemid 37093536)
70. Peters W., Cyster J. G., Mack M., Schlndorff D., Wolf A. J., Ernst J. D., Charo I. F., CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis Journal of Immunology 2004 172 12 7647 7653 (Pubitemid 38747630)
71. Deshmane S. L., Kremlev S., Amini S., Sawaya B. E., Monocyte chemoattractant protein-1 (MCP-1): an overview Journal of Interferon and Cytokine Research 2009 29 6 313 326
72. Tsuboi N., Yoshikai Y., Matsuo S., Kikuchi T., Iwami K. I., Nagai Y., Takeuchi O., Akira S., Matsuguchi T., Roles of Toll-like receptors in C-C chemokine production by renal tubular epithelial cells Journal of Immunology 2002 169 4 2026 2033 (Pubitemid 34857667)
73. Fietta A. M., Morosini M., Meloni F., Bianco A. M., Pozzi E., Pharmacological analysis of signal transduction pathways required for Mycobacterium tuberculosis -induced iL-8 and MCP-1 production in human peripheral monocytes Cytokine 2002 19 5 242 249 (Pubitemid 35257824)
74. Hasan Z., Cliff J. M., Dockrell H. M., Jamil B., Irfan M., Ashraf M., Hussain R., CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis PLoS One 2009 4 12 1 10
75. Siveke J. T., Hamann A., T helper 1 and T helper 2 cells respond differentially to chemokines Journal of Immunology 1998 160 2 550 554 (Pubitemid 28049291)
76. Mendez A., Hernandez-Pando R., Contreras S., Aguilar D., Rook G. A. W., CCL2, CCL18 and sIL-4R in renal, meningeal and pulmonary TB; a 2 year study of patients and contacts Tuberculosis 2011 91 2 140 145
77. Hussain R., Ansari A., Talat N., Hasan Z., Dawood G., CCL2/MCP-I genotype-phenotype relationship in latent tuberculosis infection PLoS One 2011 6 10 1 7
78. Chensue S. W., Warmington K. S., Allenspach E. J., Lu B., Gerard C., Kunkel S. L., Lukacs N. W., Differential expression and cross-regulatory function of RANTES during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granulomatous inflammation Journal of Immunology 1999 163 1 165 173 (Pubitemid 29295838)
79. Vesosky B., Rottinghaus E. K., Stromberg P., Turner J., Beamer G., CCL5 participates in early protection against Mycobacterium tuberculosis Journal of Leukocyte Biology 2010 87 6 1153 1165
80. Badewa A. P., Quinton L. J., Shellito J. E., Mason C. M., Chemokine receptor 5 and its ligands in the immune response to murine tuberculosis Tuberculosis 2005 85 3 185 195 (Pubitemid 40585807)
81. Kellar K. L., Gehrke J., Weis S. E., Multiple cytokines are released when blood from patients with tuberculosis is stimulated with Mycobacterium tuberculosis antigens PLoS One 2011 6 11 1 17
82. Unsal E., Aksaray S., Koksal D., Sipit T., Potential role of interleukin 6 in reactive thrombocytosis and acute phase response in pulmonary tuberculosis Postgraduate Medical Journal 2005 81 959 604 607 (Pubitemid 41297919)
83. Guler R., Parihar S. P., Spohn G., Johansen P., Brombacher F., Bachmann M. F., Blocking IL-1 but not IL-1 increases susceptibility to chronic Mycobacterium tuberculosis infection in mice Vaccine 2011 29 6 1339 1346
84. Zhang Y., Rom W. N., Regulation of the interleukin-1 (IL-1 ) gene by mycobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL6 motifs Molecular and Cellular Biology 1993 13 6 3831 3837 (Pubitemid 23157320)
85. Kindler V., Sappino A. P., Grau G. E., Piguet P. F., Vassalli P., The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection Cell 1989 56 5 731 740 (Pubitemid 19082507)
86. Flynn J. L., Goldstein M. M., Chan J., Triebold K. J., Pfeffer K., Lowenstein C. J., Schreiber R., Mak T. W., Bloom B. R., Tumor necrosis factor- is required in the protective immune response against Mycobacterium tuberculosis in mice Immunity 1995 2 6 561 572
87. Roach D. R., Bean A. G. D., Demangel C., France M. P., Briscoe H., Britton W. J., TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection Journal of Immunology 2002 168 9 4620 4627 (Pubitemid 34441368)
88. Macmicking J. D., North R. J., Lacourse R., Mudgett J. S., Shah S. K., Nathan C. F., Identification of nitric oxide synthase as a protective locus against tuberculosis Proceedings of the National Academy of Sciences of the United States of America 1997 94 10 5243 5248 (Pubitemid 27214768)
89. Cooper A. M., Pearl J. E., Brooks J. V., Ehlers S., Orme I. M., Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung Infection and Immunity 2000 68 12 6879 6882 (Pubitemid 32463397)
90. Cooper A. M., Dalton D. K., Stewart T. A., Griffin J. P., Russell D. G., Orme I. M., Disseminated tuberculosis in interferon gene-disrupted mice Journal of Experimental Medicine 1993 178 6 2243 2247 (Pubitemid 23344885)
91. Akira S., Kishimoto T., IL-6 and NF-IL6 in acute-phase response and viral infection Immunological Reviews 1992 127 25 50
92. Bernad A., Kopf M., Kulbacki R., Weich N., Koehler G., Gutierrez-Ramos J. C., Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system Immunity 1994 1 9 725 731
93. Kishimoto T., Akira S., Taga T., Interleukin-6 and its receptor: a paradigm for cytokines Science 1992 258 5082 593 597
94. Saunders B. M., Frank A. A., Orme I. M., Cooper A. M., Interleukin-6 induces early gamma interferon production in the infected lung but is not required for generation of specific immunity to Mycobacterium tuberculosis infection Infection and Immunity 2000 68 6 3322 3326 (Pubitemid 30340426)
95. Appelberg R., Castro A. G., Pedrosa J., Minoprio P., Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice Immunology 1994 82 3 361 364 (Pubitemid 24251616)
96. Jones G. W., McLoughlin R. M., Hammond V. J., Parker C. R., Williams J. D., Malhotra R., Scheller J., Williams A. S., Rose-John S., Topley N., Jones S. A., Loss of CD4 + T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells Journal of Immunology 2010 184 4 2130 2139
97. Leal I. S., Smedegard B., Andersen P., Appelberg R., Interleukin-6 and interleukin-12 participate in induction of a type 1 protective T-cell response during vaccination with a tuberculosis subunit vaccine Infection and Immunity 1999 67 11 5747 5754 (Pubitemid 29508094)
98. Pompei L., Jang S., Zamlynny B., Ravikumar S., McBride A., Hickman S. P., Salgame P., Disparity in IL-12 release in dendritic cells and macrophages in response to Mycobacterium tuberculosis is due to use of distinct TLRs Journal of Immunology 2007 178 8 5192 5199 (Pubitemid 46595303)
99. Giacomini E., Iona E., Ferroni L., Miettinen M., Fattorini L., Orefici G., Julkunen I., Coccia E. M., Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response Journal of Immunology 2001 166 12 7033 7041 (Pubitemid 32525572)
100. Hickman S. P., Chan J., Salgame P., Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization Journal of Immunology 2002 168 9 4636 4642 (Pubitemid 34441370)
101. Filipe-Santos O., Bustamante J., Chapgier A., Vogt G., de Beaucoudrey L., Feinberg J., Jouanguy E., Boisson-Dupuis S., Fieschi C., Picard C., Casanova J. L., Inborn errors of IL-12/23- and IFN- -mediated immunity: molecular, cellular, and clinical features Seminars in Immunology 2006 18 6 347 361
102. Khader S. A., Gaffen S. L., Kolls J. K., Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa Mucosal Immunology 2009 2 5 403 411
103. Sergejeva S., Ivanov S., Lotvall J., Lindén A., Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation American Journal of Respiratory Cell and Molecular Biology 2005 33 3 248 253 (Pubitemid 41254291)
104. Kolls J. K., Lindén A., Interleukin-17 family members and inflammation Immunity 2004 21 4 467 476 (Pubitemid 39370503)
105. Miyamoto M., Prause O., Sjostrand M., Laan M., Lotvall J., Lindén A., Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways Journal of Immunology 2003 170 9 4665 4672 (Pubitemid 36519973)
106. Khader S. A., Gopal R., IL-17 in protective immunity to intracellular pathogens Virulence 2010 1 5 423 427
107. Khader S. A., Guglani L., Rangel-Moreno J., IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung Journal of Immunology 2011 187 10 5402 5407
108. Roach D. R., Briscoe H., Saunders B., France M. P., Riminton S., Britton W. J., Secreted lymphotoxin- is essential for the control of an intracellular bacterial infection Journal of Experimental Medicine 2001 193 2 239 246 (Pubitemid 32524455)
109. Caccamo N., Meraviglia S., la Mendola C., Guggino G., Dieli F., Salerno A., Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens Journal of Immunology 2006 177 3 1780 1785 (Pubitemid 44092515)
110. Chackerian A. A., Alt J. M., Perera T. V., Dascher C. C., Behar S. M., Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity Infection and Immunity 2002 70 8 4501 4509 (Pubitemid 34790962)
111. Bhatt K., Hickman S. P., Salgame P., Cutting edge: a new approach to modelling early lung immunity in murine tuberculosis Journal of Immunology 2004 172 5 2748 2751 (Pubitemid 38263657)
112. Abadie V., Badell E., Douillard P., Ensergueix D., Leenen P. J. M., Tanguy M., Fiette L., Saeland S., Gicquel B., Winter N., Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes Blood 2005 106 5 1843 1850 (Pubitemid 41208603)
113. Wolf A. J., Desvignes L., Linas B., Banaiee N., Tamura T., Takatsu K., Ernst J. D., Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs Journal of Experimental Medicine 2008 205 1 105 115 (Pubitemid 351185719)
114. Reiley W. W., Calayag M. D., Wittmer S. T., Huntington J. L., Pearl J. E., Fountain J. J., Martino C. A., Roberts A. D., Cooper A. M., Winslow G. M., Woodland D. L., ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes Proceedings of the National Academy of Sciences of the United States of America 2008 105 31 10961 10966
115. Demangel C., Bertolino P., Britton W. J., Autocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 production European Journal of Immunology 2002 32 4 994 1002 (Pubitemid 34428814)
116. Li L., Qiao D., Fu X., Identification of M. tuberculosis -specific Th1 cells expressing CD69 generated in vivo in pleural fluid cells from patients with tuberculous pleurisy PLoS One 2011 6 8 1 11
117. Khader S. A., Cooper A. M., IL-23 and IL-17 in tuberculosis Cytokine 2008 41 2 79 83
118. Shen F., Hu Z., Goswami J., Gaffen S. L., Identification of common transcriptional regulatory elements in interleukin-17 target genes The Journal of Biological Chemistry 2006 281 34 24138 24148 (Pubitemid 44274188)
119. Stern J. N. H., Keskin D. B., Romero V., Zuniga J., Encinales L., Li C., Awad C., Yunis E. J., Molecular signatures distinguishing active from latent tuberculosis in peripheral blood mononuclear cells, after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD) or Candida: a preliminary report Immunologic Research 2009 45 1 1 12
120. Gor D. O., Rose N. R., Greenspan N. S., Th1Th2: a procrustean paradigm Nature Immunology 2003 4 6 503 505
121. Kidd P., Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease Alternative Medicine Review 2003 8 3 223 246 (Pubitemid 37099886)
122. Ehlers S., Kaufmann S. H., Participants of the 99th Dahlem Conference, Infection, inflammation, and chronic diseases: consequences of a modern lifestyle Trends in Immunology 2010 31 5 184 190
123. Acosta-Rodriguez E. V., Napolitani G., Lanzavecchia A., Sallusto F., Interleukins 1 and 6 but not transforming growth factor- are essential for the differentiation of interleukin 17-producing human T helper cells Nature Immunology 2007 8 9 942 949 (Pubitemid 47300008)
124. Chen Z., Tato C. M., Muul L., Laurence A., O'Shea J. J., Distinct regulation of interleukin-17 in human T helper lymphocytes Arthritis and Rheumatism 2007 56 9 2936 2946 (Pubitemid 47502740)
125. Wilson N. J., Boniface K., Chan J. R., McKenzie B. S., Blumenschein W. M., Mattson J. D., Basham B., Smith K., Chen T., Morel F., Lecron J. C., Kastelein R. A., Cua D. J., McClanahan T. K., Bowman E. P., Malefyt R. D. W., Development, cytokine profile and function of human interleukin 17-producing helper T cells Nature Immunology 2007 8 9 950 957 (Pubitemid 47300009)
126. Aggarwal S., Ghilardi N., Xie M. H., de Sauvage F. J., Gurney A. L., Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 The Journal of Biological Chemistry 2003 278 3 1910 1914 (Pubitemid 36801431)
127. Lockhart E., Green A. M., Flynn J. L., IL-17 production is dominated by T cells rather than CD4 T cells during Mycobacterium tuberculosis infection Journal of Immunology 2006 177 7 4662 4669 (Pubitemid 44469799)
128. Kirwan S. E., Burshtyn D. N., Regulation of natural killer cell activity Current Opinion in Immunology 2007 19 1 46 54 (Pubitemid 46073701)
129. Vankayalapati R., Wizel B., Weis S. E., Safi H., Lakey D. L., Mandelboim O., Samten B., Porgador A., Barnes P. F., The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium Journal of Immunology 2002 168 7 3451 3457 (Pubitemid 34250410)
130. Garg A., Barnes P. F., Porgador A., Roy S., Wu S., Nanda J. S., Griffith D. E., Girard W. M., Rawal N., Shetty S., Vankayalapati R., Vimentin expressed on Mycobacterium tuberculosis -infected human monocytes is involved in binding to the NKp46 receptor Journal of Immunology 2006 177 9 6192 6198 (Pubitemid 44628837)
131. Dhiman R., Indramohan M., Barnes P. F., Nayak R. C., Paidipally P., Rao L. V. M., Vankayalapati R., IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion Journal of Immunology 2009 183 10 6639 6645
132. Daniel T. M., Oxtoby M. J., Pinto E., Moreno E., The immune spectrum in patients with pulmonary tuberculosis American Review of Respiratory Disease 1981 123 5 556 559 (Pubitemid 11098398)
133. Costello D. A. M., Kumar A., Narayan V., Akbar M. S., Ahmed S., Abou-Zeid C., Rook G. A. W., Stanford J., Moreno C., Does antibody to mycobacterial antigens, including lipoarabinomannan, limit dissemination in childhood tuberculosis? Transactions of the Royal Society of Tropical Medicine and Hygiene 1992 86 6 686 692 (Pubitemid 23012938)
134. Barrera L., De Kantor I., Ritacco V., Reniero A., Lopez B., Benetucci J., Beltran M., Libonatti O., Padula E., Castagnino J., Gonzalez Montaner L., Humoral response to Mycobacterium tuberculosis in patients with human immunodeficiency virus infection Tubercle and Lung Disease 1992 73 4 187 191
135. da Costa C. T. K. A., Khanolkar-Young S., Elliott A. M., Wasunna K. M. A., McAdam K. P. W. J., Immunoglobulin G subclass responses to mycobacterial lipoarabinomannan in HIV-infected and non-infected patients with tuberculosis Clinical and Experimental Immunology 1993 91 1 25 29 (Pubitemid 23027992)
136. Delgado J. C., Tsai E. Y., Thim S., Baena A., Boussiotis V. A., Reynes J.
137. Pier G. L. J., Wetzler L., Cell Mediated Immunity 2004 Washigton, DC, USA American Society for Microbiology Pres. edited by J. B. L. Gerald Bryan Pier, Lee M. Wetzler
138. Abebe F., Bjune G., The protective role of antibody responses during Mycobacterium tuberculosis infection Clinical and Experimental Immunology 2009 157 2 235 243
139. Modlin R. L., Gersuk G. M., Nelson E. E., T-lymphocyte clones from leprosy skin lesions Leprosy Review 1986 57 2 143 147 (Pubitemid 17038385)
140. Clay H., Volkman H. E., Ramakrishnan L., Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death Immunity 2008 29 2 283 294
141. Aguas A. P., Esaguy N., Sunkel C. E., Silva M. T., Cross-reactivity and sequence homology between the 65-kilodalton mycobacterial heat shcok protein and human lactoferrin, transferrin, and DR() subsets of major histocompatibility complex class II molecules Infection and Immunity 1990 58 5 1461 1470 (Pubitemid 20151816)
142. Sousa A. O., Salem J. I., Lee F. K., Vercosa M. C., Cruaud P., Bloom B. R., Lagrange P. H., David H. L., An epidemic of tuberculosis with a high rate of tuberculin anergy among a population previously unexposed to tuberculosis, the Yanomami Indians of the Brazilian Amazon Proceedings of the National Academy of Sciences of the United States of America 1997 94 24 13227 13232 (Pubitemid 27518504)
143. Glatman-Freedman A., Casadevall A., Serum therapy for tuberculosis revisited: reappraisal of the role of antibody-mediated immunity against Mycobacterium tuberculosis Clinical Microbiology Reviews 1998 11 3 514 532 (Pubitemid 28379098)
144. Jasmer R. M., Nahid P., Hopewell P. C., Clinical practice. Latent tuberculosis infection The New England Journal of Medicine 2002 347 23 1860 1866 (Pubitemid 35417778)
145. Boussiotis V. A., Tsai E. Y., Yunis E. J., Thim S., Delgado J. C., Dascher C. C., Berezovskaya A., Roussec D., Reynes J. M., Goldfeld A. E., IL-10-producing T cells suppress immune responses in anergic tuberculosis patients The Journal of Clinical Investigation 2000 105 9 1317 1325 (Pubitemid 30266085)
146. Harris J., de Haro S. A., Master S. S., Keane J., Roberts E. A., Delgado M., Deretic V., T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis Immunity 2007 27 3 505 517 (Pubitemid 47418681)
147. Encinales L., Zuiga J., Granados-Montiel J., Yunis M., Granados J., Almeciga I., Clavijo O., Awad C., Collazos V., Vargas-Rojas M. I., Baales-Mendez J. L., Vazquez-Castaeda L., Stern J. N., Romero V., Frindkis-Hareli M., Terreros D., Fernandez-Via M., Yunis E. J., Humoral immunity in tuberculin skin test anergy and its role in high-risk persons exposed to active tuberculosis Molecular Immunology 2010 47 5 1066 1073
148. Snchez-Rodrquez C., Estrada-Chvez C., Garca-Vigil J., Laredo-Snchez F., Halabe-Cherem J., Pereira-Surez A., Mancilla R., An IgG antibody response to the antigen 85 complex is associated with good outcome in Mexican Totonaca Indians with pulmonary tuberculosis International Journal of Tuberculosis and Lung Disease 2002 6 8 706 712 (Pubitemid 34832151)
149. Teitelbaum R., Glatman-Freedman A., Chen B., Robbins J. B., Unanue E., Casadevall A., Bloom B. R., A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival Proceedings of the National Academy of Sciences of the United States of America 1998 95 26 15688 15693 (Pubitemid 29018761)
150. Hamasur B., Haile M., Pawlowski A., Schroder U., Kallenius G., Svenson S. B., A mycobacterial lipoarabinomannan specific monoclonal antibody and its F(ab')2 fragment prolong survival of mice infected with Mycobacterium tuberculosis Clinical and Experimental Immunology 2004 138 1 30 38 (Pubitemid 39279962)
151. Olivares N., Puig A., Aguilar D., Moya A., Cdiz A., Otero O., Izquierdo L., Falero G., Solis R. L., Orozco H., Sarmiento M. E., Norazmi M. N., Hernndez-Pando R., Acosta A., Prophylactic effect of administration of human gamma globulins in a mouse model of tuberculosis Tuberculosis 2009 89 3 218 220
152. Balu S., Reljic R., Lewis M. J., Pleass R. J., McIntosh R., van Kooten C., van Egmond M., Challacombe S., Woof J. M., Ivanyi J., A novel human IgA monoclonal antibody protects against tuberculosis Journal of Immunology 2011 186 5 3113 3119
153. Schlesinger L. S., Hull S. R., Kaufman T. M., Binding of the terminal mannosyl units of lipoarabinomannan from a virulent strain of Mycobacterium tuberculosis to human macrophages Journal of Immunology 1994 152 8 4070 4079 (Pubitemid 24111079)
154. Armstrong J. A., Hart P. D., Phagosome lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival Journal of Experimental Medicine 1975 142 1 1 16
155. Fine P. E. M., Variation in protection by BCG: implications of and for heterologous immunity The Lancet 1995 346 8986 1339 1345
156. Flynn J. L., Chan J., Immune evasion by Mycobacterium tuberculosis: living with the enemy Current Opinion in Immunology 2003 15 4 450 455 (Pubitemid 36930083)
157. Vergne I., Fratti R. A., Hill P. J., Chua J., Belisle J., Deretic V., Mycobacterium tuberculosis phagosome maturation arrest: mycobacterial phosphatidylinositol analog phosphatidylinositol mannoside stimulates early endosomal fusion Molecular Biology of the Cell 2004 15 2 751 760 (Pubitemid 38146490)
158. Sturgill-Koszycki S., Schlesinger P. H., Chakraborty P., Haddix P. L., Collins H. L., Fok A. K., Allen R. D., Gluck S. L., Heuser J., Russell D. G., Lack of acidification in Mycobacterium phagosomes produced by exclusion vesicular proton-ATPase Science 1994 263 5147 678 681
159. Ferrari G., Langen H., Naito M., Pieters J., A coat protein on phagosomes involved in the intracellular survival of mycobacteria Cell 1999 97 4 435 447 (Pubitemid 29231167)
160. Jayachandran R., Sundaramurthy V., Combaluzier B., Mueller P., Korf H., Huygen K., Miyazaki T., Albrecht I., Massner J., Pieters J., Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin Cell 2007 130 1 37 50 (Pubitemid 47031320)
161. Bryk R., Lima C. D., Erdjument-Bromage H., Tempst P., Nathan C., Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein Science 2002 295 5557 1073 1077 (Pubitemid 34132237)
162. Pai P. K., Convery M., Hamilton T. A., Boom W. H., Harding C. V., Inhibition of IFN-gamma-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion Journal of Immunology 2003 171 1 175 184 (Pubitemid 36745286)
163. Pai R. K., Pennini M. E., Tobian A. A. R., Canaday D. H., Boom W. H., Harding C. V., Prolonged Toll-like receptor signaling by Mycobacterium tuberculosis and its 19-kilodalton lipoprotein inhibits gamma interferon-induced regulation of selected genes in macrophages Infection and Immunity 2004 72 11 6603 6614 (Pubitemid 39425443)
164. Sendide K., Deghmane A. E., Pechkovsky D., Av-Gay Y., Talal A., Hmama Z., Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S Journal of Immunology 2005 175 8 5324 5332 (Pubitemid 41456418)
165. Kumar D., Nath L., Kamal M. A., Varshney A., Jain A., Singh S., Rao K. V. S., Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis Cell 2010 140 5 731 743
166. Gutierrez M. G., Master S. S., Singh S. B., Taylor G. A., Colombo M. I., Deretic V., Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages Cell 2004 119 6 753 766 (Pubitemid 40017683)
167. Shin D. M., Jeon B. Y., Lee H. M., Jin H. S., Yuk J. M., Song C. H., Lee S. H., Lee Z. W., Cho S. N., Kim J. M., Friedman R. L., Jo E. K., Mycobacterium tuberculosis eis regulates autophagy, inflammation, and cell death through redox-dependent signaling PLoS Pathogens 2010 6 12 1 15
168. Garca-Romo G. S., Pedroza-Gonzlez A., Aguilar-Leon D., Orozco-Estevez H., Lambrecht B. N., Estrada-Garcia I., Flores-Romo L., Hernndez-Pando R., Airways infection with virulent Mycobacterium tuberculosis delays the influx of dendritic cells and the expression of costimulatory molecules in mediastinal lymph nodes Immunology 2004 112 4 661 668 (Pubitemid 39061492)
169. Wolf A. J., Linas B., Trevejo-Nuez G. J., Kincaid E., Tamura T., Takatsu K., Ernst J. D., Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo Journal of Immunology 2007 179 4 2509 2519
170. Casanova J. L., Abel L., Genetic dissection of immunity to mycobacteria: the human model Annual Review of Immunology 2002 20 581 620 (Pubitemid 34293435)
171. Cooper A. M., Cell-mediated immune responses in tuberculosis Annual Review of Immunology 2009 27 393 422
172. Bold T. D., Banaei N., Wolf A. J., Ernst J. D., Suboptimal activation of antigen-specific CD4 + effector cells enables persistence of M. tuberculosis in vivo PLoS Pathogens 2011 7 5 1 13
173. Jurado J. O., Alvarez I. B., Pasquinelli V., Martnez G. J., Quiroga M. F., Abbate E., Musella R. M., Chuluyan H. E., Garca V. E., Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis Journal of Immunology 2008 181 1 116 125
174. Santos-Mendoza T., Silva-Snchez A., Meza-Pérez S., Neumann L., Meier S., Experimental pulmonary tuberculosis and immune inhibitory signals: a role for PD1-PD1-ligand interplay Veterinary Immunology and Immunopathology 2010 New York, NY, USA Nova Science Pubulisher
175. Zandman-Goddard G., Shoenfeld Y., Infections and SLE Autoimmunity 2005 38 7 473 485 (Pubitemid 43101781)
176. Doran M. F., Crowson C. S., Pond G. R., O'Fallon W. M., Gabriel S. E., Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study Arthritis and Rheumatism 2002 46 9 2287 2293
177. Brassard P., Kezouh A., Suissa S., Antirheumatic drugs and the risk of tuberculosis Clinical Infectious Diseases 2006 43 6 717 722 (Pubitemid 44330734)
178. Borchers A. T., Leibushor N., Cheema G. S., Naguwa S. M., Gershwin M. E., Immune-mediated adverse effects of biological used in the treatment of rheumatic diseases Journal of Autoimmunity 2011 37 4 273 288
179. Askling J., Fored C. M., Brandt L., Baecklund E., Bertilsson L., Coster L., Geborek P., Jacobsson L. T., Lindblad S., Lysholm J., Rantapaa-Dahlqvist S., Saxne T., Romanus V., Klareskog L., Feltelius N., Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden Arthritis and Rheumatism 2005 52 7 1986 1992 (Pubitemid 40994319)
180. Gmez-Reino J. J., Carmona L., Rodrguez Valverde V., Mola E. M., Montero M. D., Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report Arthritis and Rheumatism 2003 48 8 2122 2127 (Pubitemid 36959191)
181. Dixon W. G., Hyrich K. L., Watson K. D., Lunt M., Galloway J., Ustianowski A., Symmons D. P. M., Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register (BSRBR) Annals of the Rheumatic Diseases 2010 69 3 522 528
182. Keane J., Gershon S., Wise R. P., Mirabile-Levens E., Kasznica J., Schwieterman W. D., Siegel J. N., Braun M. M., Tuberculosis associated with infliximab, a tumor necrosis factor -neutralizing agent The New England Journal of Medicine 2001 345 15 1098 1104
183. Mewar D., Wilson A. G., Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors British Journal of Pharmacology 2011 162 4 785 791
184. Tubach F., Salmon D., Ravaud P., Allanore Y., Goupille P., Bréban M., Pallot-Prades B., Pouplin S., Sacchi A., Chichemanian R. M., Bretagne S., Emilie D., Lemann M., Lorthololary O., Mariette X., Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: the three-year prospective French research axed on tolerance of biotherapies registry Arthritis and Rheumatism 2009 60 7 1884 1894
185. Strand V., Mease P., Burmester G. R., Nikai E., Coteur G., van Vollenhoven R., Combe B., Keystone E. C., Kavanaugh A., Rapid and sustained improvements in health-related quality of life, fatigue, and other patient-reported outcomes in rheumatoid arthritis patients treated with certolizumab pegol plus methotrexate over 1 year: results from the RAPID 1 randomized controlled trial Arthritis Research and Therapy 2009 11 6 1 12
186. Strand V., Smolen J. S., van Vollenhoven R. F., Mease P., Burmester G. R., Hiepe F., Khanna D., Nikai E., Coteur G., Schiff M., Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient-reported outcomes from the RAPID 2 trial Annals of the Rheumatic Diseases 2011 70 6 996 1002
187. Emery P., Fleischmann R. M., Moreland L. W., Hsia E. C., Strusberg I., Durez P., Nash P., Amante E. J. B., Churchill M., Park W., Pons-Estel B. A., Doyle M. K., Visvanathan S., Xu W., Rahman M. U., Golimumab, a human anti-tumor necrosis factor monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis Arthritis and Rheumatism 2009 60 8 2272 2283
188. Vla L. E., Frattl R. A., McFalone M., Pagn-Ramos E., Deretic D., Deretic V., Effects of cytokines on mycobacterial phagosome maturation Journal of Cell Science 1998 111 7 897 905 (Pubitemid 28196073)
189. Harris J., Hope J. C., Keane J., Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis The Journal of Infectious Diseases 2008 198 12 1842 1850
190. Andrade R. M., Wessendarp M., Gubbels M. J., Striepen B., Subauste C. S., CD40 induces macrophage anti- Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes The Journal of Clinical Investigation 2006 116 9 2366 2377 (Pubitemid 44330135)
191. Djavaheri-Mergny M., Amelotti M., Mathieu J., Besancon F., Bauvy C., Souquere S., Pierron G., Codogno P., NF- B activation represses tumor necrosis factor- -induced autophagy The Journal of Biological Chemistry 2006 281 41 30373 30382 (Pubitemid 44582093)
192. Jia G., Cheng G., Gangahar D. M., Agrawal D. K., Insulin-like growth factor-1 and TNF- regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells Immunology and Cell Biology 2006 84 5 448 454 (Pubitemid 44286038)
193. ten Hove T., van Montfrans C., Peppelenbosch M. P., van Deventer S. J. H., Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease Gut 2002 50 2 206 211 (Pubitemid 34087933)
194. di Sabatino A., Ciccocioppo R., Cinque B., Millimaggi D., Morera R., Ricevuti L., Cifone M. G., Corazza G. R., Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease Gut 2004 53 1 70 77 (Pubitemid 38083013)
195. Bruns H., Meinken C., Schauenberg P., Harter G., Kern P., Modlin R. L., Antoni C., Stenger S., Anti-TNF immunotherapy reduces CD8 + T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans The Journal of Clinical Investigation 2009 119 5 1167 1177
196. Mitoma H., Horiuchi T., Hatta N., Tsukamoto H., Harashima S. I., Kikuchi Y., Otsuka J., Okamura S., Fujita S., Harada M., Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF- Gastroenterology 2005 128 2 376 392 (Pubitemid 40431090)
197. Mitoma H., Horiuchi T., Tsukamoto H., Tamimoto Y., Kimoto Y., Uchino A., To K., Harashima S. I., Hatta N., Harada M., Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor -expressing cells: comparison among infliximab, etanercept, and adalimumab Arthritis and Rheumatism 2008 58 5 1248 1257 (Pubitemid 351705913)
198. Saliu O. Y., Sofer C., Stein D. S., Schwander S. K., Wallis R. S., Tumor-necrosis-factor blockers: differential effects on mycobacterial immunity The Journal of Infectious Diseases 2006 194 4 486 492 (Pubitemid 44162660)
199. Hamdi H., Mariette X., Godot V., Weldingh K., Hamid A. M., Prejean M. V., Baron G., Lemann M., Puechal X., Breban M., Berenbaum F., Delchier J. C., Flipo R. M., Dautzenberg B., Salmon D., Humbert M., Emilie D., Meyer O., Falgarone G., Chaussade P., Desreumaux X., Liote F., Claudepierre P., Portier A., Bacchi V. F., Inhibition of anti-tuberculosis T-lymphocyte function with tumour necrosis factor antagonists Arthritis Research and Therapy 2006 8 4, article R114 1 15
200. Cope A. P., Londei M., Chu N. R., Cohen S. B. A., Elliott M. J., Brennan F. M., Maini R. N., Feldmann M., Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis The Journal of Clinical Investigation 1994 94 2 749 760
201. Berg L., Lampa J., Rogberg S., van Vollenhoven R., Klareskog L., Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNF receptors Annals of the Rheumatic Diseases 2001 60 2 133 139 (Pubitemid 32102204)
202. Baeten D., van Damme N., van den Bosch F., Kruithof E., de Vos M., Mielants H., Veys E. M., de Keyser F., Impaired Th1 cytokine production in spondyloarthropathy is restored by anti-TNF Annals of the Rheumatic Diseases 2001 60 8 750 755 (Pubitemid 32685875)
203. Zou J. X., Braun J., Sieper J., Immunological basis for the use of TNF -blocking agents in ankylosing spondylitis and immunological changes during treatment Clinical and Experimental Rheumatology 2002 20 6 S34 S37
204. Malaviya R., Sun Y., Tan J. K., Wang A., Magliocco M., Yao M., Krueger J. G., Gottlieb A. B., Etanercept induces apoptosis of dermal dendritic cells in psoriatic plaques of responding patients Journal of the American Academy of Dermatology 2006 55 4 590 597 (Pubitemid 44436644)
205. Shen C., Assche G. V., Colpaert S., Maerten P., Geboes K., Rutgeerts P., Ceuppens J. L., Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept Alimentary Pharmacology and Therapeutics 2005 21 3 251 258 (Pubitemid 40278362)