Potential role of interleukin 6 in reactive thrombocytosis and acute phase response in pulmonary tuberculosis

Postgraduate Medical Journal

Volumn 81, Issue 959, 2005, Pages 604-607

  Unsal E ^b   Aksaray, S ^c   Koksal D ^a,b   Sipit T ^b  

^a Atatürk Chest Diseases and Chest Surgery Education and Research Hospital ^*  (Turkey)

^b Ataturk Chest Disease and Thoracic Surgery Education and Research Hospital Ankara   (Turkey)

^c ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; INTERLEUKIN 6;

ACUTE PHASE RESPONSE; ADULT; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FEVER; HUMAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; NIGHT SWEAT; THORAX RADIOGRAPHY; THROMBOCYTE COUNT; THROMBOCYTOSIS; WEIGHT REDUCTION;

ACUTE-PHASE REACTION; ADULT; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; FEMALE; HUMANS; INTERLEUKIN-6; MALE; PLATELET COUNT; SERUM ALBUMIN; THROMBOCYTOSIS; TUBERCULOSIS, PULMONARY;

EID: 24744453474     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pgmj.2004.030544     Document Type: Article

References (24)

1. Tefferi A, Ho TC, Ahmann GJ, et al. Plasma interleukin 6 and C reactive protein levels in reactive versus clonal thrombocytosis. Am J Med 1994;97:374-8.
2. Turken O, Kunter E, Sezer M, et al. Hemostatic changes in active pulmonary tuberculosis. Int J Tuberc Lung Dis 2002;6:927-32.
3. Baynes RD, Boyhwell TH, Flax H, et al. Reactive thrombocytosis in pulmonary tuberculosis. J Clin Pathol 1987;40:676-9.
4. Hollen CW, Henthorn J, Koziol JA, et al. Elevated serum interleukin 6 levels in patients with reactive thrombocytosis. Br J Haematol 1991;79:286-90.
5. Kaser A, Brandacher G, Steurer W, et al. Interleukin 6 stimulates thrombopoiesis through thrombopoietin: role in inflammatory thrombocytosis. Blood 2001;98:2720-5.
6. Bauer J, Herrmann F. Interleukin 6 in clinical medicine. Ann Hematol 1991;62:203-10.
7. Kishimoto T. The biology of interleukin 6. Blood 1989;74:1-10.
8. Kimura H, Ishibashi T, Uchida T, et al. Interleukin 6 is a differentiation factor for human megakaryocytes in vitro. Eur J Immunol 1990;20:1927-31.
9. Hill RJ, Warren MK, Levin J. Stimulation of thrombopoiesis in mice by human recombinant interleukin 6. J Clin Invest 1990;85:1242-7.
10. Poveda F, Camacho J, Arnalich F, et al. Circulating cytokine concentrations in tuberculosis and other chronic bacterial infections. Infection 1999;27:272-4.
11. Orme IM, Andersen P, Boom WH. T cell response to Mycobacterium tuberculosis. J Infect Dis 1993;167:1481-97.
12. Law K, Weiden M, Harkin T, et al. Increased release of interleukin 1 beta, interleukin 6 and tumor necrosis factor alpha by bronchoalveolar cells lavaged from involved sites in pulmonary tuberculosis. Am J Respir Crit Care Med 1996;153:799-804.
13. Ogawa T, Uchida H, Kusumoto Y, et al. Increase in tumor necrosis factor alpha and interleukin 6 secreting cells in peripheral blood mononuclear cells from subjects infected with Mycobacterium tuberculosis. Infect Immun 1991;59:3021-5.
14. Haznedaroǧlu IC, Ertenli I, Özcebe OI, et al. Megakaryocyte related interleukins in reactive thrombocytosis versus autonomous thrombocythemia. Acta Haematol 1996;95:107-11.
15. Nakano T, Chahinian AP, Shinjo M, et al. Interleukin 6 and its relationship to clinical parameters in patients with malignant pleural mesothelioma. Br J Cancer 1998;77:907-12.
16. Yokoyama A, Maruyama M, Ito M, et al. Interleukin 6 activity in pleural effusion. Its diagnostic value and thrombopoietic activity. Chest 1992;102:1055-9.
17. Mayer P, Geissler K, Valent P, et al. Recombinant human interleukin 6 is a potent inducer of the acute phase response and elevates the blood platelets in nonhuman primates. Exp Hematol 1991;19:688-96.
18. Hoheisel G, Izbicki G, Roth M, et al. Compartmentalization of proinflammatory cytokines in tuberculous pleurisy. Respir Med 1998;92:14-17.
19. Tsao TC, Hong J, Huang C, et al. Increased TNF alpha, IL1 beta and IL6 levels in the bronchoalveolar lavage fluid with the upregulation of their mRNA in macrophages lavaged from patients with active pulmonary tuberculosis. Tuber Lung Dis 1999;79:279-5.
20. El-Ahmady O, Mansour M, Zoeir H, et al. Elevated concentrations of interleukins and leukotriene in response to Mycobacterium tuberculosis infection. Ann Clin Biochem 1997;34:160-4.
21. Robson SC, White NW, Aronson I, et al. Acute phase response and the hypercoagulable state in pulmonary tuberculosis. Br J Haematol 1996;93:943-9.
22. Evans CA, Jellis J, Hughes SP, et al. Tumor necrosis factor alpha, interleukin 6 and interleukin 8 secretion and the acute phase response in patients with bacterial and tuberculous osteomyelitis. J Infect Dis 1998;177:1582-7.
23. Nijsten MWN, de Grott ER, ten Duis HJ, et al. Serum levels of interleukin 6 and acute phase responses. Lancet 1987;ii:921.
24. Klein B, Wijdenes J, Zhang XG, et al. Murine anti-interleukin 6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 1991;78:1198-204.