-
2
-
-
0030931682
-
Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2
-
Bukowski R.M. Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2. Cancer 1997, 80:1198-1220.
-
(1997)
Cancer
, vol.80
, pp. 1198-1220
-
-
Bukowski, R.M.1
-
3
-
-
0035048096
-
Cytokine therapy for metastatic renal cell carcinoma
-
Bukowski R.M. Cytokine therapy for metastatic renal cell carcinoma. Seminars in Urology Oncology 2001, 19:148-154.
-
(2001)
Seminars in Urology Oncology
, vol.19
, pp. 148-154
-
-
Bukowski, R.M.1
-
4
-
-
0036138580
-
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
Motzer R.J., Bacik J., Murphy B.A., Russo P., Mazumdar M. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. Journal of Clinical Oncology 2002, 20:289-296.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.A.3
Russo, P.4
Mazumdar, M.5
-
5
-
-
77956598117
-
Systemic therapy for metastatic renal cell carcinoma in treatment naïve patients: a risk-based approach
-
Bukowski R.M. Systemic therapy for metastatic renal cell carcinoma in treatment naïve patients: a risk-based approach. Expert Opinion on Pharmacotherapy 2010, 11:2351-2362.
-
(2010)
Expert Opinion on Pharmacotherapy
, vol.11
, pp. 2351-2362
-
-
Bukowski, R.M.1
-
6
-
-
80055006798
-
Clinical efficacy and prognostic factors for overall survival in Japanese patients with metastatic renal cell cancer treated with sunitinib
-
Yuasa T., Tsuchiya N., Urakami S., Horikawa Y., Narita S., Inoue T., Saito M., Yamamoto S., Yonese J., Fukui I., Nakano K., Takahashi S., Hatake K., Habuchi T. Clinical efficacy and prognostic factors for overall survival in Japanese patients with metastatic renal cell cancer treated with sunitinib. BJU International 2011, 105:1811-1813.
-
(2011)
BJU International
, vol.105
, pp. 1811-1813
-
-
Yuasa, T.1
Tsuchiya, N.2
Urakami, S.3
Horikawa, Y.4
Narita, S.5
Inoue, T.6
Saito, M.7
Yamamoto, S.8
Yonese, J.9
Fukui, I.10
Nakano, K.11
Takahashi, S.12
Hatake, K.13
Habuchi, T.14
-
7
-
-
84862292960
-
Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib
-
Di Fiore F., Rigal O., Menager C., Michel P., Pfister C. Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib. British Journal of Cancer 2012, 109:1349-1354.
-
(2012)
British Journal of Cancer
, vol.109
, pp. 1349-1354
-
-
Di Fiore, F.1
Rigal, O.2
Menager, C.3
Michel, P.4
Pfister, C.5
-
9
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken A.P., Dietrich N., Pasini D., Hansen K.H., Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes & Development 2006, 20:1123-1136.
-
(2006)
Genes & Development
, vol.20
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
Helin, K.5
-
10
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S., Dhanasekaran S.M., Zhou M., Barrette T.R., Kumar-Sinha C., Sanda M.G., Ghosh D., Pienta K.J., Sewalt R.G.A.B., Otte A.P., Rubin M.A., Chinnaiyan A.M. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002, 419:624.
-
(2002)
Nature
, vol.419
, pp. 624
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
Ghosh, D.7
Pienta, K.J.8
Sewalt, R.G.A.B.9
Otte, A.P.10
Rubin, M.A.11
Chinnaiyan, A.M.12
-
11
-
-
29344445843
-
Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder
-
Raman J.D., Mongan N.P., Tickoo S.K., Boorjian S.A., Scherr D.S., Gudas L.J. Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clinical Cancer Research 2005, 11:8570-8576.
-
(2005)
Clinical Cancer Research
, vol.11
, pp. 8570-8576
-
-
Raman, J.D.1
Mongan, N.P.2
Tickoo, S.K.3
Boorjian, S.A.4
Scherr, D.S.5
Gudas, L.J.6
-
12
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer C.G., Cao Q., Varambally S., Shen R., Ota I., Tomlins S.A., Ghosh D., Sewalt R.G.A.B., Otte A.P., Hayes D.F., Sabel M.S., Livant D., Weiss S.J., Rubin M.A., Chinnaiyan A.M. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proceedings of the National Academy of Sciences 2003, 100:11606-11611.
-
(2003)
Proceedings of the National Academy of Sciences
, vol.100
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
Ghosh, D.7
Sewalt, R.G.A.B.8
Otte, A.P.9
Hayes, D.F.10
Sabel, M.S.11
Livant, D.12
Weiss, S.J.13
Rubin, M.A.14
Chinnaiyan, A.M.15
-
13
-
-
70349958032
-
Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis
-
Fluge O., Gravdal K., Carlsen E., Vonen B., Kjellevold K., Refsum S., Lilleng R., Eide T.J., Halvorsen T.B., Tveit K.M., Otte A.P., Akslen L.A., Dahl O. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer 2009, 101:1282.
-
(2009)
British Journal of Cancer
, vol.101
, pp. 1282
-
-
Fluge, O.1
Gravdal, K.2
Carlsen, E.3
Vonen, B.4
Kjellevold, K.5
Refsum, S.6
Lilleng, R.7
Eide, T.J.8
Halvorsen, T.B.9
Tveit, K.M.10
Otte, A.P.11
Akslen, L.A.12
Dahl, O.13
-
14
-
-
58149214373
-
Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2
-
Ougolkov A.V., Bilim V.N., Billadeau D.D. Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2. Clinical Cancer Research 2008, 14:6790-6796.
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 6790-6796
-
-
Ougolkov, A.V.1
Bilim, V.N.2
Billadeau, D.D.3
-
15
-
-
77957282672
-
Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
-
Wagener N., Macher-Goeppinger S., Pritsch M., Husing J., Hoppe-Seyler K., Schirmacher P., Pfitzenmaier J., Haferkamp A., Hoppe-Seyler F., Hohenfellner M. Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma. BMC Cancer 2010, 10:524.
-
(2010)
BMC Cancer
, vol.10
, pp. 524
-
-
Wagener, N.1
Macher-Goeppinger, S.2
Pritsch, M.3
Husing, J.4
Hoppe-Seyler, K.5
Schirmacher, P.6
Pfitzenmaier, J.7
Haferkamp, A.8
Hoppe-Seyler, F.9
Hohenfellner, M.10
-
16
-
-
71849116150
-
Expression profile of the polycomb group protein enhancer of zeste homologue 2 and its prognostic relevance in renal cell carcinoma
-
Hinz S., Weikert S., Magheli A., Hoffmann M., Engers R., Miller K., Kempkensteffen C. Expression profile of the polycomb group protein enhancer of zeste homologue 2 and its prognostic relevance in renal cell carcinoma. The Journal of Urology 2009, 182:2920.
-
(2009)
The Journal of Urology
, vol.182
, pp. 2920
-
-
Hinz, S.1
Weikert, S.2
Magheli, A.3
Hoffmann, M.4
Engers, R.5
Miller, K.6
Kempkensteffen, C.7
-
17
-
-
84355162040
-
Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3beta
-
Tsukigi M., Bilim V., Yuuki K., Ugolkov A., Naito S., Nagaoka A., Kato T., Motoyama T., Tomita Y. Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3beta. Cancer Letters 2012, 315:189-197.
-
(2012)
Cancer Letters
, vol.315
, pp. 189-197
-
-
Tsukigi, M.1
Bilim, V.2
Yuuki, K.3
Ugolkov, A.4
Naito, S.5
Nagaoka, A.6
Kato, T.7
Motoyama, T.8
Tomita, Y.9
-
18
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402.
-
(2001)
Methods
, vol.25
, pp. 402
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
20
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally S., Cao Q., Mani R.-S., Shankar S., Wang X., Ateeq B., Laxman B., Cao X., Jing X., Ramnarayanan K., Brenner J.C., Yu J., Kim J.H., Han B., Tan P., Kumar-Sinha C., Lonigro R.J., Palanisamy N., Maher C.A., Chinnaiyan A.M. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008, 322:1695-1699.
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.-S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
Laxman, B.7
Cao, X.8
Jing, X.9
Ramnarayanan, K.10
Brenner, J.C.11
Yu, J.12
Kim, J.H.13
Han, B.14
Tan, P.15
Kumar-Sinha, C.16
Lonigro, R.J.17
Palanisamy, N.18
Maher, C.A.19
Chinnaiyan, A.M.20
more..
-
21
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman J.M., Liang G., Liu C.-C., Wolff E.M., Tsai Y.C., Ye W., Zhou X., Jones P.A. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Research 2009, 69:2623-2629.
-
(2009)
Cancer Research
, vol.69
, pp. 2623-2629
-
-
Friedman, J.M.1
Liang, G.2
Liu, C.-C.3
Wolff, E.M.4
Tsai, Y.C.5
Ye, W.6
Zhou, X.7
Jones, P.A.8
-
22
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman R.C., Farh K.K.-H., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Research 2009, 19:92-105.
-
(2009)
Genome Research
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.-H.2
Burge, C.B.3
Bartel, D.P.4
-
23
-
-
28344440823
-
MicroRNA function: multiple mechanisms for a tiny RNA?
-
Pillai R.S. MicroRNA function: multiple mechanisms for a tiny RNA?. RNA 2005, 11:1753-1761.
-
(2005)
RNA
, vol.11
, pp. 1753-1761
-
-
Pillai, R.S.1
-
24
-
-
44449148691
-
Oxidative stress, DNA methylation and carcinogenesis
-
Franco R., Schoneveld O., Georgakilas A.G., Panayiotidis M.I. Oxidative stress, DNA methylation and carcinogenesis. Cancer Letters 2008, 266:6.
-
(2008)
Cancer Letters
, vol.266
, pp. 6
-
-
Franco, R.1
Schoneveld, O.2
Georgakilas, A.G.3
Panayiotidis, M.I.4
-
25
-
-
32844459336
-
The polycomb group protein EZH2 directly controls DNA methylation
-
Vire E., Brenner C., Deplus R., Blanchon L., Fraga M., Didelot C., Morey L., Van Eynde A., Bernard D., Vanderwinden J.-M., Bollen M., Esteller M., Di Croce L., de Launoit Y., Fuks F. The polycomb group protein EZH2 directly controls DNA methylation. Nature 2006, 439:871.
-
(2006)
Nature
, vol.439
, pp. 871
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.-M.10
Bollen, M.11
Esteller, M.12
Di Croce, L.13
de Launoit, Y.14
Fuks, F.15
-
26
-
-
50549103560
-
The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
-
Wagener N., Holland D., Bulkescher J., Crnković-Mertens I., Hoppe-Seyler K., Zentgraf H., Pritsch M., Buse S., Pfitzenmaier J., Haferkamp A., Hohenfellner M., Hoppe-Seyler F. The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells. International Journal of Cancer 2008, 123:1545-1550.
-
(2008)
International Journal of Cancer
, vol.123
, pp. 1545-1550
-
-
Wagener, N.1
Holland, D.2
Bulkescher, J.3
Crnković-Mertens, I.4
Hoppe-Seyler, K.5
Zentgraf, H.6
Pritsch, M.7
Buse, S.8
Pfitzenmaier, J.9
Haferkamp, A.10
Hohenfellner, M.11
Hoppe-Seyler, F.12
-
27
-
-
79958756075
-
Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma
-
Avissar-Whiting M., Koestler D.C., Houseman E.A., Christensen B.C., Kelsey K.T., Marsit C.J. Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma. Epigenetics 2011, 6:703-709.
-
(2011)
Epigenetics
, vol.6
, pp. 703-709
-
-
Avissar-Whiting, M.1
Koestler, D.C.2
Houseman, E.A.3
Christensen, B.C.4
Kelsey, K.T.5
Marsit, C.J.6
-
28
-
-
0025128367
-
Immunohistochemical detection of major histocompatibility complex antigens and quantitative analysis of tumour-infiltrating mononuclear cells in renal cell cancer
-
Tomita Y., Nishiyama T., Fujiwara M., Sato S. Immunohistochemical detection of major histocompatibility complex antigens and quantitative analysis of tumour-infiltrating mononuclear cells in renal cell cancer. British Journal of Cancer 1990, 62:354-359.
-
(1990)
British Journal of Cancer
, vol.62
, pp. 354-359
-
-
Tomita, Y.1
Nishiyama, T.2
Fujiwara, M.3
Sato, S.4
-
29
-
-
79955729316
-
Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy
-
Sasaki D., Imaizumi Y., Hasegawa H., Osaka A., Tsukasaki K., Choi Y.L., Mano H., Marquez V.E., Hayashi T., Yanagihara K., Moriwaki Y., Miyazaki Y., Kamihira S., Yamada Y. Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy. Haematologica 2011, 96:712-719.
-
(2011)
Haematologica
, vol.96
, pp. 712-719
-
-
Sasaki, D.1
Imaizumi, Y.2
Hasegawa, H.3
Osaka, A.4
Tsukasaki, K.5
Choi, Y.L.6
Mano, H.7
Marquez, V.E.8
Hayashi, T.9
Yanagihara, K.10
Moriwaki, Y.11
Miyazaki, Y.12
Kamihira, S.13
Yamada, Y.14
-
30
-
-
79551541972
-
Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2
-
Smits M., Mir S.E., Nilsson R.J.A., van der Stoop P.M., Niers J.M., Marquez V.E., Cloos J., Breakefield X.O., Krichevsky A.M., Noske D.P., Tannous B.A., Würdinger T. Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. PLoS ONE 2011, 6:e16282.
-
(2011)
PLoS ONE
, vol.6
-
-
Smits, M.1
Mir, S.E.2
Nilsson, R.J.A.3
van der Stoop, P.M.4
Niers, J.M.5
Marquez, V.E.6
Cloos, J.7
Breakefield, X.O.8
Krichevsky, A.M.9
Noske, D.P.10
Tannous, B.A.11
Würdinger, T.12
|