Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio

Toxicology and Applied Pharmacology

Volumn 262, Issue 2, 2012, Pages 185-193

  Hamdi, Mohamad ^a   Yoshinaga, Masafumi ^b   Packianathan, Charles ^b   Qin, Jie ^b   Hallauer, Janell ^a   McDermott, Joseph R ^a   Yang, Hung Chi ^c   Tsai, Kan Jen ^d   Liu, Zijuan ^a  

^a OAKLAND UNIVERSITY   (United States)

^b FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Arsenic; Arsenite; DMA V; GSH; HPLC ICP MS; Methylation; MMA III; MMA V; SAM; Selenite; Zebrafish

Indexed keywords

ARSENIC METHYLTRANSFERASE; ARSENIC TRIOXIDE; METHYLTRANSFERASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ESCHERICHIA COLI; IN VITRO STUDY; INTESTINE; LIVER; METHYLATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; WESTERN BLOTTING; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; ARSENICALS; ARSENITES; BASE SEQUENCE; CLONING, MOLECULAR; FEMALE; MALE; METHYLATION; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; RNA, MESSENGER; S-ADENOSYLMETHIONINE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SODIUM SELENITE; ZEBRAFISH;

DANIO RERIO; ESCHERICHIA COLI; MAMMALIA; RODENTIA; VERTEBRATA;

EID: 84862266270     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.04.035     Document Type: Article

References (44)

1. Agusa T., Iwata H., Fujihara J., Kunito T., Takeshita H., Minh T.B., Trang P.T., Viet P.H., Tanabe S. Genetic polymorphisms in AS3MT and arsenic metabolism in residents of the Red River Delta, Vietnam. Toxicol. Appl. Pharmacol. 2009, 236:131-141.
2. Amatruda J.F., Patton E.E. Genetic models of cancer in zebrafish. Int. Rev. Cell Mol. Biol. 2008, 271:1-34.
3. Antman K.H. Introduction: the history of arsenic trioxide in cancer therapy. Oncologist 2001, 6(Suppl. 2):1-2.
4. Basu A., Mitra S., Chung J., Guha Mazumder D.N., Ghosh N., Kalman D., von Ehrenstein O.S., Steinmaus C., Liaw J., Smith A.H. Creatinine, diet, micronutrients, and arsenic methylation in West Bengal, India. Environ. Health Perspect. 2011, 119:1308-1313.
5. Beene L.C., Halluer J., Yoshinaga M., Hamdi M., Liu Z. Pentavalent Arsenate Transport by Zebrafish Phosphate Transporter NaPi-IIb1. Zebrafish 2011, 8(3):125-131.
6. Bun-ya M., Shikata K., Nakade S., Yompakdee C., Harashima S., Oshima Y. Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr. Genet. 1996, 29:344-351.
7. Chung C.J., Hsueh Y.M., Bai C.H., Huang Y.K., Huang Y.L., Yang M.H., Chen C.J. Polymorphisms in arsenic metabolism genes, urinary arsenic methylation profile and cancer. Cancer Causes Control 2009, 20:1653-1661.
8. de The H., Chen Z. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure. Nat. Rev. Cancer 2010, 10:775-783.
9. Drobna Z., Waters S.B., Walton F.S., LeCluyse E.L., Thomas D.J., Styblo M. Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes. Toxicol. Appl. Pharmacol. 2004, 201:166-177.
10. Drobna Z., Waters S.B., Devesa V., Harmon A.W., Thomas D.J., Styblo M. Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase. Toxicol. Appl. Pharmacol. 2005, 207:147-159.
11. Drobna Z., Naranmandura H., Kubachka K.M., Edwards B.C., Herbin-Davis K., Styblo M., Le X.C., Creed J.T., Maeda N., Hughes M.F., Thomas D.J. Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate. Chem. Res. Toxicol. 2009, 22:1713-1720.
12. Engstrom K., Vahter M., Mlakar S.J., Concha G., Nermell B., Raqib R., Cardozo A., Broberg K. Polymorphisms in arsenic(+III oxidation state) methyltransferase (AS3MT) predict gene expression of AS3MT as well as arsenic metabolism. Environ. Health Perspect. 2011, 119:182-188.
13. Gomez-Rubio P., Roberge J., Arendell L., Harris R.B., O'Rourke M.K., Chen Z., Cantu-Soto E., Meza-Montenegro M.M., Billheimer D., Lu Z., Klimecki W.T. Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest Mexico. Toxicol. Appl. Pharmacol. 2011, 252:176-182.
14. Hamdi M., Sanchez M.A., Beene L.C., Liu Q., Landfear S.M., Rosen B.P., Liu Z. Arsenic transport by zebrafish aquaglyceroporins. BMC Mol. Biol. 2009, 10:104.
15. Hirano S., Kobayashi Y., Cui X., Kanno S., Hayakawa T., Shraim A. The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds. Toxicol. Appl. Pharmacol. 2004, 198:458-467.
16. Hughes M.F. Arsenic methylation, oxidative stress and cancer-is there a link?. J. Natl. Cancer Inst. 2009, 101:1660-1661.
17. Jomova K., Jenisova Z., Feszterova M., Baros S., Liska J., Hudecova D., Rhodes C.J., Valko M. Arsenic: toxicity, oxidative stress and human disease. J. Appl. Toxicol. 2011, 31:95-107.
18. Katsoyiannis I.A., Hug S.J., Ammann A., Zikoudi A., Hatziliontos C. Arsenic speciation and uranium concentrations in drinking water supply wells in Northern Greece: correlations with redox indicative parameters and implications for groundwater treatment. Sci. Total Environ. 2007, 383:128-140.
19. Kitchin K.T., Conolly R. Arsenic-induced carcinogenesis-oxidative stress as a possible mode of action and future research needs for more biologically based risk assessment. Chem. Res. Toxicol. 2010, 23:327-335.
20. Kojima C., Ramirez D.C., Tokar E.J., Himeno S., Drobna Z., Styblo M., Mason R.P., Waalkes M.P. Requirement of arsenic biomethylation for oxidative DNA damage. J. Natl. Cancer Inst. 2009, 101:1670-1681.
21. Kwong R.C., Karagas M.R., Kelsey K.T., Mason R.A., Tanyos S.A., Schned A.R., Marsit C.J., Andrew A.S. Arsenic exposure predicts bladder cancer survival in a US population. World J. Urol. 2010, 28:487-492.
22. Lam S.H., Wu Y.L., Vega V.B., Miller L.D., Spitsbergen J., Tong Y., Zhan H., Govindarajan K.R., Lee S., Mathavan S., Murthy K.R., Buhler D.R., Liu E.T., Gong Z. Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. Nat. Biotechnol. 2006, 24:73-75.
23. Larabee J.L., Hocker J.R., Hanas R.J., Kahn F.M., Hanas J.S. Inhibition of zinc finger protein-DNA interactions by sodium selenite. Biochem. Pharmacol. 2002, 64:1757-1765.
24. Liu J., Chen H., Miller D.S., Saavedra J.E., Keefer L.K., Johnson D.R., Klaassen C.D., Waalkes M.P. Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic. Mol. Pharmacol. 2001, 60:302-309.
25. Liu Z., Shen J., Carbrey J.M., Mukhopadhyay R., Agre P., Rosen B.P. Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:6053-6058.
26. Liu Z., Sanchez M.A., Jiang X., Boles E., Landfear S.M., Rosen B.P. Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid. Biochem. Biophys. Res. Commun. 2006, 351:424-430.
27. Marapakala K., Qin J., Rosen B.P. Identification of catalytic residues in the as(iii) s-adenosylmethionine methyltransferase. Biochemistry 2012, 51:944-951.
28. Meng X.Y., Qin J., Wang L.H., Duan G.L., Sun G.X., Wu H.L., Chu C.C., Ling H.Q., Rosen B.P., Zhu Y.G. Arsenic biotransformation and volatilization in transgenic rice. New Phytol. 2011, 191:49-56.
29. Nguyen A.T., Emelyanov A., Koh C.H., Spitsbergen J.M., Parinov S., Gong Z. An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening. Dis. Model. Mech. 2011, 5(1):63-72.
30. Petrick J.S., Ayala-Fierro F., Cullen W.R., Carter D.E., Vasken Aposhian H. Monomethylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes. Toxicol. Appl. Pharmacol. 2000, 163:203-207.
31. Qin J., Rosen B.P., Zhang Y., Wang G., Franke S., Rensing C. Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2075-2080.
32. Qin J., Lehr C.R., Yuan C., Le X.C., McDermott T.R., Rosen B.P. Biotransformation of arsenic by a Yellowstone thermoacidophilic eukaryotic alga. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:5213-5217.
33. Rehman K., Naranmandura H. Arsenic metabolism and thioarsenicals. Metallomics 2012, 10.1039/C2MT00181K.
34. Ren X., Aleshin M., Jo W.J., Dills R., Kalman D.A., Vulpe C.D., Smith M.T., Zhang L. Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity. Environ. Health Perspect. 2011, 119:771-777.
35. Song X., Geng Z., Li X., Hu X., Bian N., Zhang X., Wang Z. New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT). Biochimie 2010, 92:1397-1406.
36. Song X., Geng Z., Li X., Zhao Q., Hu X., Zhang X., Wang Z. Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT). Biochimie 2011, 93:369-375.
37. Styblo M., Drobna Z., Jaspers I., Lin S., Thomas D.J. The role of biomethylation in toxicity and carcinogenicity of arsenic: a research update. Environ. Health Perspect. 2002, 110(Suppl. 5):767-771.
38. Thomas D.J., Waters S.B., Styblo M. Elucidating the pathway for arsenic methylation. Toxicol. Appl. Pharmacol. 2004, 198:319-326.
39. Tseng C.H. Arsenic methylation, urinary arsenic metabolites and human diseases: current perspective. J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. 2007, 25:1-22.
40. Tseng C.H. Cardiovascular disease in arsenic-exposed subjects living in the arseniasis-hyperendemic areas in Taiwan. Atherosclerosis 2008, 199:12-18.
41. Valenzuela O.L., Drobna Z., Hernandez-Castellanos E., Sanchez-Pena L.C., Garcia-Vargas G.G., Borja-Aburto V.H., Styblo M., Del Razo L.M. Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions. Toxicol. Appl. Pharmacol. 2009, 239:200-207.
42. Waters S.B., Devesa V., Fricke M.W., Creed J.T., Styblo M., Thomas D.J. Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine. Chem. Res. Toxicol. 2004, 17:1621-1629.
43. Wnek S.M., Jensen T.J., Severson P.L., Futscher B.W., Gandolfi A.J. Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12weeks of low-level exposure. Toxicol. Sci. 2010, 116:44-57.
44. Ye J., Rensing C., Rosen B.P., Zhu Y.G. Arsenic biomethylation by photosynthetic organisms. Trends Plant Sci. 2012, 17(3):155-162.