메뉴 건너뛰기




Volumn 39, Issue 7, 2012, Pages 617-624

Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir-145

Author keywords

Decitabine (5 aza 2 deoxycytidine); DNA demethylation; Doxorubicin; Keratinocytes; mir 145; Oct4

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DOXORUBICIN; MICRORNA 145; OCTAMER TRANSCRIPTION FACTOR 4;

EID: 84862251333     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2012.01553.x     Document Type: Article
Times cited : (8)

References (31)
  • 1
    • 77749320143 scopus 로고    scopus 로고
    • Generation of mouse-induced pluripotent stem cells with plasmid vectors
    • Okita K, Hong H, Takahashi K, Yamanaka S. Generation of mouse-induced pluripotent stem cells with plasmid vectors. Nat Protoc 2010; 5: 418-428.
    • (2010) Nat Protoc , vol.5 , pp. 418-428
    • Okita, K.1    Hong, H.2    Takahashi, K.3    Yamanaka, S.4
  • 3
    • 65449154892 scopus 로고    scopus 로고
    • Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
    • Yusa K, Rad R, Takeda J, Bradley A. Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 2009; 6: 363-369.
    • (2009) Nat Methods , vol.6 , pp. 363-369
    • Yusa, K.1    Rad, R.2    Takeda, J.3    Bradley, A.4
  • 4
    • 60649084367 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Current progress and potential for regenerative medicine
    • Amabile G, Meissner A. Induced pluripotent stem cells: current progress and potential for regenerative medicine. Trends Mol Med 2009; 15: 59-68.
    • (2009) Trends Mol Med , vol.15 , pp. 59-68
    • Amabile, G.1    Meissner, A.2
  • 5
    • 79952488548 scopus 로고    scopus 로고
    • Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway
    • Racila D, Winter M, Said M et al. Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway. Gene Ther 2011 18, 294-303.
    • (2011) Gene Ther , vol.18 , pp. 294-303
    • Racila, D.1    Winter, M.2    Said, M.3
  • 6
    • 2342437315 scopus 로고    scopus 로고
    • Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells
    • Hattori N, Nishino K, Ko YG, Ohgane J, Tanaka S, Shiota K. Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem 2004; 279: 17063-17069.
    • (2004) J Biol Chem , vol.279 , pp. 17063-17069
    • Hattori, N.1    Nishino, K.2    Ko, Y.G.3    Ohgane, J.4    Tanaka, S.5    Shiota, K.6
  • 7
    • 79954563768 scopus 로고    scopus 로고
    • Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx
    • Dhawan S, Georgia S, Tschen SI, Fan G, Bhushan A. Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell 2011; 20: 419-429.
    • (2011) Dev Cell , vol.20 , pp. 419-429
    • Dhawan, S.1    Georgia, S.2    Tschen, S.I.3    Fan, G.4    Bhushan, A.5
  • 8
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy
    • Christman JK. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 2002; 21: 5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 9
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009; 137: 647-658.
    • (2009) Cell , vol.137 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 10
    • 79959994661 scopus 로고    scopus 로고
    • Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells
    • Wu Y, Liu S, Xin H et al. Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells. Cancer 2011; 117: 3989-3998.
    • (2011) Cancer , vol.117 , pp. 3989-3998
    • Wu, Y.1    Liu, S.2    Xin, H.3
  • 11
    • 79954545144 scopus 로고    scopus 로고
    • microRNA-145 suppresses lung adenocarcinoma- Initiating cell proliferation by targeting OCT4
    • Yin R, Zhang S, Wu Y et al. microRNA-145 suppresses lung adenocarcinoma- initiating cell proliferation by targeting OCT4. Oncol Rep 2011; 25: 1747-1754.
    • (2011) Oncol Rep , vol.25 , pp. 1747-1754
    • Yin, R.1    Zhang, S.2    Wu, Y.3
  • 12
    • 53549133376 scopus 로고    scopus 로고
    • Oct4? Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells
    • Card DA, Hebbar PB, Li L et al. Oct4 ? Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol 2008; 28: 6426-6438.
    • (2008) Mol Cell Biol , vol.28 , pp. 6426-6438
    • Card, D.A.1    Hebbar, P.B.2    Li, L.3
  • 13
    • 2942534403 scopus 로고    scopus 로고
    • Human embryonic stem cells express a unique set of microRNAs
    • Suh MR, Lee Y, Kim JY et al. Human embryonic stem cells express a unique set of microRNAs. Dev Biol 2004; 270: 488-498.
    • (2004) Dev Biol , vol.270 , pp. 488-498
    • Suh, M.R.1    Lee, Y.2    Kim, J.Y.3
  • 14
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M, Zhu S, Wu F et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106: 3207-3212.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 15
    • 67449100820 scopus 로고    scopus 로고
    • Chemical decomposition of 5-aza-2′-deoxycytidine (Decitabine): Kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry
    • Rogstad DK, Herring JL, Theruvathu JA et al. Chemical decomposition of 5-aza-2′-deoxycytidine (Decitabine): kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry. Chem Res Toxicol 2009; 22: 1194-1204.
    • (2009) Chem Res Toxicol , vol.22 , pp. 1194-1204
    • Rogstad, D.K.1    Herring, J.L.2    Theruvathu, J.A.3
  • 16
    • 0031964055 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth of human tumor cell lines
    • Bender CM, Pao MM, Jones PA. Inhibition of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res 1998; 58: 95-101.
    • (1998) Cancer Res , vol.58 , pp. 95-101
    • Bender, C.M.1    Pao, M.M.2    Jones, P.A.3
  • 17
    • 84855446143 scopus 로고    scopus 로고
    • 5-azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase
    • Qian Q, Qian H, Zhang X et al. 5-azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase. Stem Cells Dev 2011; 21: 67-75.
    • (2011) Stem Cells Dev , vol.21 , pp. 67-75
    • Qian, Q.1    Qian, H.2    Zhang, X.3
  • 18
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C, Police S, Rao N, Carpenter MK. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res 2002; 91: 501-508.
    • (2002) Circ Res , vol.91 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 19
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 2008; 40: 1478-1483.
    • (2008) Nat Genet , vol.40 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.E.4    Baehner, L.5    Blelloch, R.6
  • 20
    • 66249139268 scopus 로고    scopus 로고
    • Cell cycle regulation by MicroRNAs in embryonic stem cells
    • Wang Y, Blelloch R. Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res 2009; 69: 4093-4096.
    • (2009) Cancer Res , vol.69 , pp. 4093-4096
    • Wang, Y.1    Blelloch, R.2
  • 22
    • 33744975288 scopus 로고    scopus 로고
    • Cell cycle features of primate embryonic stem cells
    • Fluckiger AC, Marcy G, Marchand M et al. Cell cycle features of primate embryonic stem cells. Stem Cells 2006; 24: 547-556.
    • (2006) Stem Cells , vol.24 , pp. 547-556
    • Fluckiger, A.C.1    Marcy, G.2    Marchand, M.3
  • 23
    • 52949125268 scopus 로고    scopus 로고
    • Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin SL, Chang DC, Chang-Lin S et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 2008; 14: 2115-2124.
    • (2008) RNA , vol.14 , pp. 2115-2124
    • Lin, S.L.1    Chang, D.C.2    Chang-Lin, S.3
  • 24
    • 77957039745 scopus 로고    scopus 로고
    • Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: A Children's Oncology Group study
    • George RE, Lahti JM, Adamson PC et al. Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer 2010; 55: 629-638.
    • (2010) Pediatr Blood Cancer , vol.55 , pp. 629-638
    • George, R.E.1    Lahti, J.M.2    Adamson, P.C.3
  • 25
    • 63349098439 scopus 로고    scopus 로고
    • DNA methyltransferase I is a mediator of doxorubicin-induced genotoxicity in human cancer cells
    • Tan HH, Porter AG. DNA methyltransferase I is a mediator of doxorubicin-induced genotoxicity in human cancer cells. Biochem Biophys Res Commun 2009; 382: 462-467.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 462-467
    • Tan, H.H.1    Porter, A.G.2
  • 27
    • 13844280894 scopus 로고    scopus 로고
    • Oct4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis
    • Tai MH, Chang CC, Kiupel M, Webster JD, Olson LK, Trosko JE. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis 2005; 26: 495-502.
    • (2005) Carcinogenesis , vol.26 , pp. 495-502
    • Tai, M.H.1    Chang, C.C.2    Kiupel, M.3    Webster, J.D.4    Olson, L.K.5    Trosko, J.E.6
  • 28
    • 79960805359 scopus 로고    scopus 로고
    • Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma
    • Tsai LL, Yu CC, Chang YC, Yu CH, Chou MY. Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma. J Oral Pathol Med 2011; 40: 621-628.
    • (2011) J Oral Pathol Med , vol.40 , pp. 621-628
    • Tsai, L.L.1    Yu, C.C.2    Chang, Y.C.3    Yu, C.H.4    Chou, M.Y.5
  • 29
    • 84856377986 scopus 로고    scopus 로고
    • Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo
    • doi: 10.1002/ijc.26320
    • Alcazar O, Achberger S, Aldrich W et al. Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo. Int J Cancer 2011; doi: 10.1002/ijc.26320.
    • (2011) Int J Cancer
    • Alcazar, O.1    Achberger, S.2    Aldrich, W.3
  • 30
    • 0028328854 scopus 로고
    • Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine
    • Weber J, Salgaller M, Samid D et al. Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine. Cancer Res 1994; 54: 1766-1771.
    • (1994) Cancer Res , vol.54 , pp. 1766-1771
    • Weber, J.1    Salgaller, M.2    Samid, D.3
  • 31
    • 1642454589 scopus 로고    scopus 로고
    • Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine
    • Karpf AR, Lasek AW, Ririe TO, Hanks AN, Grossman D, Jones DA. Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine. Mol Pharmacol 2004; 65: 18-27.
    • (2004) Mol Pharmacol , vol.65 , pp. 18-27
    • Karpf, A.R.1    Lasek, A.W.2    Ririe, T.O.3    Hanks, A.N.4    Grossman, D.5    Jones, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.