Effect of Sulforaphane on Growth Inhibition in Human Brain Malignant Glioma GBM 8401 Cells by Means of Mitochondrial- and MEK/ERK-Mediated Apoptosis Pathway

Cell Biochemistry and Biophysics

Volumn 63, Issue 3, 2012, Pages 247-259

  Huang, Tzuu Yuan ^a   Chang, Weng Cheng ^b   Wang, Miin Yau ^b   Yang, Yun Ru ^b   Hsu, Yi Chiang ^b  

^a TAINAN SIN LAU HOSPITAL   (Taiwan)

^b CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Malignant glioma; MEK ERK pathway; Mitochondrial; Sulforaphane

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SULFORAFAN; THIOCYANIC ACID DERIVATIVE;

ANIMAL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; G1 PHASE CELL CYCLE CHECKPOINT; GLIOMA; HUMAN; METABOLISM; MOUSE; MOUSE MUTANT; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G1 PHASE CELL CYCLE CHECKPOINTS; GLIOMA; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, SCID; NF-KAPPA B; THIOCYANATES; TRANSPLANTATION, HETEROLOGOUS;

MUS;

EID: 84862243016     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-012-9360-3     Document Type: Article

References (39)

1. Mukherjee, S., Bhattacharya, R. K., & Roy, M. (2009). Targeting protein kinase C (PKC) and telomerase by phenethyl isothiocyanate (PEITC) sensitizes PC-3 cells towards chemotherapeutic drug-induced apoptosis. Journal of Environmental Pathology, Toxicology and Oncology, 28(4), 269-282.
2. Smerák, P., Polívková, Z., Stetina, R., et al. (2009). Antimutagenic effect of phenethyl isothiocyanate. Central European Journal of Public Health, 17(2), 86-92.
3. Stan, S. D., Singh, S. V., & Brand, R. E. (2010). Chemoprevention strategies for pancreatic cancer. Nature Reviews Gastroenterology & Hepatology, 7(6), 347-356.
4. Matsuda, T., Maruyama, T., Iizuka, H., et al. (2010). Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice. Food and Chemical Toxicology, 48(6), 1704-1708.
5. Herr, I., & Büchler, M. W. (2010). Dietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer. Cancer Treatment Reviews, 36(5), 377-383.
6. Maeda, T., Miyazono, Y., Ito, K., et al. (2010). Oxidative stress and enhanced paracellular permeability in the small intestine of methotrexate-treated rats. Cancer Chemotherapy and Pharmacology, 65(6), 1117-1123.
7. Miyoshi, N., Watanabe, E., Osawa, T., et al. (2008). ATP depletion alters the mode of cell death induced by benzyl isothiocyanate. Biochimica et Biophysica Acta, 1782(10), 566-573.
8. Hasegawa, K., Miwa, S., Tsutsumiuchi, K., et al. (2010). Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS ONE, 5(2), e9267.
9. Mishra, P. K., Panwar, H., Bhargava, A., et al. (2008). Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes. Journal of Biochemical and Molecular Toxicology, 22(6), 429-440.
10. Adsule, S., Banerjee, S., Ahmed, F., et al. (2010). Hybrid anticancer agents: Isothiocyanate-progesterone conjugates as chemotherapeutic agents and insights into their cytotoxicities. Bioorganic & Medicinal Chemistry Letters, 20(3), 1247-1251.
11. Higdon, J. V., Delage, B., Williams, D. E., et al. (2007). Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis. Pharmacological Research, 55(3), 224-236.
12. Li, M., Wang, Q., Lin, W., & Wang, B. (2009). Regulation of ovarian cancer cell adhesion and invasion by chloride channels. International Journal of Gynecological Cancer, 19(4), 526-530.
13. D'Agostini, F., Mastracci, L., Izzotti, A., et al. (2009). Modulation by phenethyl isothiocyanate and budesonide of molecular and histopathologic alterations induced by environmental cigarette smoke in mice. Cancer Prevention Research (Philadelphia), 2(6), 546-556.
14. Kim, M. G., & Lee, H. S. (2009). Growth-inhibiting activities of phenethyl isothiocyanate and its derivatives against intestinal bacteria. Journal of Food Science, 74(8), M467-M471.
15. Hayashi, S., Nakamura, E., Kubo, Y., et al. (2008). Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters. Journal of Physiology and Pharmacology, 59(4), 691-706.
16. Traka, M. H., Spinks, C. A., Doleman, J. F., et al. (2010). The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer. Molecular Cancer, 13, 189.
17. Jiang, H., Shang, X., Wu, H., et al. (2010). Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochemical Research, 35(1), 152-161.
18. Jakubíková, J., Sedlák, J., Mithen, R., et al. (2005). Role of PI3 K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochemical Pharmacology, 69(11), 1543-1552.
19. Shan, Y., Wu, K., Wang, W., et al. (2009). Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells. International Journal of Oncology, 34(4), 1129-1134.
20. Choi, S., Lew, K. L., Xiao, H., et al. (2007). d, l-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1. Carcinogenesis, 28(1), 151-162.
21. Mao, L., Wang, H. D., Wang, X. L., et al. (2010). Sulforaphane attenuates matrix metalloproteinase-9 expression following spinal cord injury in mice. Annals of Clinical and Laboratory Science, 40(4), 354-360.
22. Zhu, M., Zhang, Y., Cooper, S., et al. (2004). Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism. Molecular Carcinogenesis, 41(3), 179-186.
23. Huang, T. Y., Tsai, T. H., Hsu, C. W., et al. (2010). Curcuminoids suppress the growth and induce apoptosis through caspase-3-dependent pathways in glioblastoma multiforme (GBM) 8401 cells. Journal of Agriculture and Food Chemistry, 58(19), 10639-10645.
24. Moquin, D. L., & Chan, F. K. (2010). The molecular regulation of programmed necrotic cell injury. Trends in Biochemical Sciences, 35(8), 434-441.
25. Shih, Y. W., Wu, P. F., Lee, Y. C., et al. (2009). Myricetin suppresses invasion and migration of human lung adenocarcinoma A549 cells: Possible mediation by blocking the ERK signaling pathway. Journal of Agriculture and Food Chemistry, 57(9), 3490-3499.
26. Karsy, M., Albert, L., Tobias, M. E., et al. (2010). All-trans retinoic acid modulates cancer stem cells of glioblastoma multiforme in an MAPK-dependent manner. Anticancer Research, 30(12), 4915-4920.
27. Chang, H. F., Huang, W. T., Chen, H. J., et al. (2010). Apoptotic effects of γ-mangostin from the fruit hull of Garcinia mangostana on human malignant glioma cells. Molecules, 15(12), 8953-8966.
28. Juan, H. F., Chen, J. H., Hsu, W. T., et al. (2004). Identification of tumor-associated plasma biomarkers using proteomic techniques: from mouse to human. Proteomics, 4(9), 2766-2775.
29. Lim, S. K., Llaguno, S. R., McKay, R. M., et al. (2011). Glioblastoma multiforme: A perspective on recent findings in human cancer and mouse models. BMB Reports, 44(3), 158-164.
30. Khor, T. O., Keum, Y. S., Lin, W., et al. (2006). Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Research, 66(2), 613-621.
31. Park, C., Moon, D. O., Choi, I. W., et al. (2007). Curcumin induces apoptosis and inhibits prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis. International Journal of Molecular Medicine, 20(3), 365-372.
32. Abdi, A., Sadraie, H., Dargahi, L., Khalaj, L., et al. (2011). Apoptosis inhibition can be threatening in Aβ-induced neuroinflammation, through promoting cell proliferation. Neurochemical Research, 36(1), 39-48.
33. Zhao, Y., Sui, X., & Ren, H. (2010). From procaspase-8 to caspase-8: Revisiting structural functions of caspase-8. Journal of Cellular Physiology, 225(2), 316-320.
34. Kuttan, G., Kumar, K. B., Guruvayoorappan, C., et al. (2007). Antitumor, anti-invasion, and antimetastatic effects of curcumin. Advances in Experimental Medicine and Biology, 595, 173-184.
35. Kunnumakkara, A. B., Guha, S., Krishnan, S., et al. (2007). Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Research, 67(8), 3853-3861.
36. Yoon, H., & Liu, R. H. (2007). Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cells. Journal of Agriculture and Food Chemistry, 55(8), 3167-3173.
37. Brunelli, D., Tavecchio, M., Falcioni, C., et al. (2010). The isothiocyanate produced from glucomoringin inhibits NF-κB and reduces myeloma growth in nude mice in vivo. Biochemical Pharmacology, 79(8), 1141-1148.
38. Fimognari, C., & Hrelia, P. (2007). Sulforaphane as a promising molecule for fighting cancer. Mutation Research, 635(2-3), 90-104.
39. Roy, S. K., Srivastava, R. K., & Shankar, S. (2010). Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer. Journal of Molecular Biology, 5, 10.