Human AP endonuclease/redox factor APE1/ref-1modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1

Free Radical Biology and Medicine

Volumn 53, Issue 2, 2012, Pages 237-248

  Li, Mengxia ^a   Vascotto, Carlo ^b   Xu, Shangcheng ^c   Dai, Nan ^a   Qing, Yi ^a   Zhong, Zhaoyang ^a   Tell, Gianluca ^b   Wang, Dong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF UDINE   (Italy)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

APE1; Free radicals; Mitochondrial function; NRF1; Oxidative stress

Indexed keywords

APURINIC APYRIMIDINIC ENDONUCLEASE REDOX FACTOR; CYTOCHROME C OXIDASE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; REDOX EFFECTOR FACTOR 1; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE INACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

CELL NUCLEUS; CELL RESPIRATION; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; NF-E2-RELATED FACTOR 1; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TERT-BUTYLHYDROPEROXIDE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 84862230380     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.04.002     Document Type: Article

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