Restoring assembly and activity of cystathionine β-synthase mutants by ligands and chemical chaperones

Journal of Inherited Metabolic Disease

Volumn 34, Issue 1, 2011, Pages 39-48

  Kopecká, Jana ^a   Krijt, Jakub ^a   Raková, Kateřina ^a   Kožich, Viktor ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; BETAINE; CHAPERONE; CYSTATHIONINE BETA SYNTHASE; GLYCEROL; TAURINE; TETRAMER; LIGAND; MUTANT PROTEIN;

ALLELE; ARTICLE; CONTROLLED STUDY; CYSTATHIONINE BETA SYNTHASE DEFICIENCY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ESCHERICHIA COLI; GENE MUTATION; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTANT; NONHUMAN; PROTEIN EXPRESSION; WESTERN BLOTTING; CHEMISTRY; DRUG EFFECT; EVALUATION; GENETICS; HOMOCYSTINURIA; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ACTIVITY RELATION;

ALLELES; AMINOLEVULINIC ACID; BETAINE; CYSTATHIONINE BETA-SYNTHASE; ESCHERICHIA COLI; GLYCEROL; HOMOCYSTINURIA; HUMANS; LIGANDS; MOLECULAR CHAPERONES; MUTANT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; TAURINE;

EID: 77954134566     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-010-9087-5     Document Type: Article

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