Structural effects and lipid membrane interactions of the pH-responsive GALA peptide with fatty acid acylation

Biochemistry

Volumn 51, Issue 23, 2012, Pages 4658-4668

  Lin, Brian F ^a,b,c   Missirlis, Dimitris ^a,c   Krogstad, Daniel V ^d   Tirrell, Matthew ^a,d,e  

^a University of California at Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d University of California   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC CONDITIONS; AMPHIPATHIC; CELL INTERNALIZATION; CELL VIABILITY; HYDROPHOBIC MOIETIES; INTRACELLULAR DRUG DELIVERY; LIPID MEMBRANES; PEPTIDE AMPHIPHILES; PH-RESPONSIVE; PHYSICOCHEMICAL CHARACTERISTICS; PHYSIOLOGICAL PH; RANDOM COIL; STRUCTURAL EFFECT; THERAPEUTIC DELIVERY; TRANS-MEMBRANE PORES;

DRUG DELIVERY; LIPOSOMES; PH EFFECTS; PHYSIOLOGY; POLYPEPTIDES; SURFACE ACTIVE AGENTS;

PEPTIDES;

AMPHOPHILE; FATTY ACID; GALA PROTEIN; LIPOSOME; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CARCINOMA CELL; CONJUGATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; INTERNALIZATION; LIPID MEMBRANE; LYSIS; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE;

ACYLATION; CELL LINE, TUMOR; CELL MEMBRANE; CIRCULAR DICHROISM; FATTY ACIDS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MEMBRANE LIPIDS; MICROSCOPY, ELECTRON, TRANSMISSION; PEPTIDES; PROTEIN CONFORMATION;

EID: 84862206976     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300314h     Document Type: Article

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