Ca 2+-regulatory proteins in cardiomyocytes from the right ventricle in children with congenital heart disease

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Wu, Yihe ^a   Feng, Wei ^a   Zhang, Hao ^a   Li, Shoujun ^a   Wang, De ^a   Pan, Xiangbin ^a   Hu, Shengshou ^a  

^a FUWAI HOSPITAL   (China)

Author keywords

Ca 2+ regulatory proteins; Hypertrophy; Hypoxia; Immature cardiomyocytes; Right ventricle

Indexed keywords

CALCIUM CHANNEL; MESSENGER RNA; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN SERCA 2A; RYANODINE RECEPTOR 2; SARCOLIPIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SERINE; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG; CALCIUM; CALCIUM BINDING PROTEIN;

ARTICLE; CELL SIZE; CHILD; CONGENITAL HEART DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FALLOT TETRALOGY; FEMALE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OPEN HEART SURGERY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PULMONARY VALVE STENOSIS; CONGENITAL HEART MALFORMATION; DEMOGRAPHY; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; HEART VENTRICLE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRESCHOOL CHILD; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CALCIUM; CALCIUM-BINDING PROTEINS; CELL SIZE; CHILD, PRESCHOOL; DEMOGRAPHY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; HUMANS; MALE; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84862204236     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-67     Document Type: Article

References (45)

1. Gilboa SM, Salemi JL, Nembhard WN, Fixler DE, Correa A. Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. Circulation 2010, 122:2254-2263. 10.1161/CIRCULATIONAHA.110.947002, 21098447.
2. Wang D, Liu YL, Lu XD, Zhu YB, Ling F, Liu AJ, Li G, Xu YL. Expression of ghrelin and insulin-like growth factor-1 in immature piglet model of chronic cyanotic congenital heart defects with decreased pulmonary blood flow. Chin Med J (Engl) 2011, 124:2354-2360.
3. Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol 2002, 39:1890-1900. 10.1016/S0735-1097(02)01886-7, 12084585.
4. Vittorini S, Storti S, Parri MS, Cerillo AG, Clerico A. SERCA2a, phospholamban, sarcolipin, and ryanodine receptors gene expression in children with congenital heart defects. Mol Med 2007, 13:105-111. 1869624, 17515962.
5. Nef HM, Mollmann H, Troidl C, Kostin S, Voss S, Hilpert P, Behrens CB, Rolf A, Rixe J, Weber M, et al. Abnormalities in intracellular Ca2+ regulation contribute to the pathomechanism of Tako-Tsubo cardiomyopathy. Eur Heart J 2009, 30:2155-2164. 10.1093/eurheartj/ehp240, 19525500.
6. Qi M, Shannon TR, Euler DE, Bers DM, Samarel AM. Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophy. Am J Physiol 1997, 272:H2416-H2424.
7. Bartelds B, Borgdorff MA, Smit-van Oosten A, Takens J, Boersma B, Nederhoff MG, Elzenga NJ, van Gilst WH, De Windt LJ, Berger RM. Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. Eur J Heart Fail 2011,
8. Wong K, Boheler KR, Bishop J, Petrou M, Yacoub MH. Clenbuterol induces cardiac hypertrophy with normal functional, morphological and molecular features. Cardiovasc Res 1998, 37:115-122. 10.1016/S0008-6363(97)00190-9, 9539865.
9. Okayama H, Hamada M, Kawakami H, Ikeda S, Hashida H, Shigematsu Y, Hiwada K. Alterations in expression of sarcoplasmic reticulum gene in Dahl rats during the transition from compensatory myocardial hypertrophy to heart failure. J Hypertens 1997, 15:1767-1774. 10.1097/00004872-199715120-00087, 9488237.
10. Sharma S, Taegtmeyer H, Adrogue J, Razeghi P, Sen S, Ngumbela K, Essop MF. Dynamic changes of gene expression in hypoxia-induced right ventricular hypertrophy. Am J Physiol Heart Circ Physiol 2004, 286:H1185-H1192.
11. Bansal DD, Klein RM, Hausmann EH, MacGregor RR. Secretion of cardiac plasminogen activator during hypoxia-induced right ventricular hypertrophy. J Mol Cell Cardiol 1997, 29:3105-3114. 10.1006/jmcc.1997.0536, 9405184.
12. Ronkainen VP, Skoumal R, Tavi P. Hypoxia and HIF-1 suppress SERCA2a expression in embryonic cardiac myocytes through two interdependent hypoxia response elements. J Mol Cell Cardiol 2011, 50:1008-1016. 10.1016/j.yjmcc.2011.02.017, 21382378.
13. Kubo H, Margulies KB, Piacentino V. Gaughan JP, Houser SR: Patients with end-stage congestive heart failure treated with beta-adrenergic receptor antagonists have improved ventricular myocyte calcium regulatory protein abundance. Circulation 2001, 104:1012-1018. 10.1161/hc3401.095073, 11524394.
14. Chen J, Hu CF, Hou JH, Shao Q, Yan LX, Zhu XF, Zeng YX, Shao JY. Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma. J Transl Med 2010, 8:30. 10.1186/1479-5876-8-30, 2861642, 20338061.
15. Care A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P, Bang ML, Segnalini P, Gu Y, Dalton ND, et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med 2007, 13:613-618. 10.1038/nm1582, 17468766.
16. Wu YH, Wang J, Gong DX, Gu HY, Hu SS, Zhang H. Effects of low-level laser irradiation on mesenchymal stem cell proliferation: a microarray analysis. Lasers Med Sci 2011,
17. Jiang HK, Qiu GR, Li-Ling J, Xin N, Sun KL. Reduced ACTC1 expression might play a role in the onset of congenital heart disease by inducing cardiomyocyte apoptosis. Circ J 2010, 74:2410-2418. 10.1253/circj.CJ-10-0234, 20962418.
18. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008, 3:1101-1108. 10.1038/nprot.2008.73, 18546601.
19. Hullin R, Asmus F, Ludwig A, Hersel J, Boekstegers P. Subunit expression of the cardiac L-type calcium channel is differentially regulated in diastolic heart failure of the cardiac allograft. Circulation 1999, 100:155-163. 10.1161/01.CIR.100.2.155, 10402445.
20. Sun C, Zhao X, Xu K, Gong J, Liu W, Ding W, Gou Y, Xia G, Ding Q. Periostin: a promising target of therapeutical intervention for prostate cancer. J Transl Med 2011, 9:99. 10.1186/1479-5876-9-99, 3146429, 21714934.
21. Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. Transient regenerative potential of the neonatal mouse heart. Science 2011, 331:1078-1080. 10.1126/science.1200708, 3099478, 21350179.
22. Boerth SR, Zimmer DB, Artman M. Steady-state mRNA levels of the sarcolemmal Na(+)-Ca2+ exchanger peak near birth in developing rabbit and rat hearts. Circ Res 1994, 74:354-359. 10.1161/01.RES.74.2.354, 8293573.
23. Chen F, Ding S, Lee BS, Wetzel GT. Sarcoplasmic reticulum Ca(2+)ATPase and cell contraction in developing rabbit heart. J Mol Cell Cardiol 2000, 32:745-755. 10.1006/jmcc.2000.1116, 10775480.
24. Lompre AM, Lambert F, Lakatta EG, Schwartz K. Expression of sarcoplasmic reticulum Ca(2+)-ATPase and calsequestrin genes in rat heart during ontogenic development and aging. Circ Res 1991, 69:1380-1388. 10.1161/01.RES.69.5.1380, 1834363.
25. Vetter R, Studer R, Reinecke H, Kolar F, Ostadalova I, Drexler H. Reciprocal changes in the postnatal expression of the sarcolemmal Na + -Ca(2+)-exchanger and SERCA2 in rat heart. J Mol Cell Cardiol 1995, 27:1689-1701. 10.1016/S0022-2828(95)90788-2, 8523431.
26. DiPaola NR, Sweet WE, Stull LB, Francis GS. Schomisch Moravec C: Beta-adrenergic receptors and calcium cycling proteins in non-failing, hypertrophied and failing human hearts: transition from hypertrophy to failure. J Mol Cell Cardiol 2001, 33:1283-1295. 10.1006/jmcc.2001.1390, 11444930.
27. Apitz C, Webb GD, Redington AN. Tetralogy of Fallot. Lancet 2009, 374:1462-1471. 10.1016/S0140-6736(09)60657-7, 19683809.
28. Kouchoukos NT, Blackstone EH, Doty DB, Hanley FL, Karp RB. Kirklin/Barratt-Boyes Cardiac Surgery 2003, p.852. Churchill Livingstone, Philadelphia.
29. Gupta SC, Varian KD, Bal NC, Abraham JL, Periasamy M, Janssen PM. Pulmonary artery banding alters the expression of Ca2+ transport proteins in the right atrium in rabbits. Am J Physiol Heart Circ Physiol 2009, 296:H1933-H1939. 10.1152/ajpheart.00026.2009, 2716096, 19376811.
30. Song LS, Pi Y, Kim SJ, Yatani A, Guatimosim S, Kudej RK, Zhang Q, Cheng H, Hittinger L, Ghaleh B, et al. Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circ Res 2005, 97:457-464. 10.1161/01.RES.0000179722.79295.d4, 16051885.
31. Wong K, Boheler KR, Petrou M, Yacoub MH. Pharmacological modulation of pressure-overload cardiac hypertrophy: changes in ventricular function, extracellular matrix, and gene expression. Circulation 1997, 96:2239-2246. 10.1161/01.CIR.96.7.2239, 9337196.
32. Carvalho BM, Bassani RA, Franchini KG, Bassani JW. Enhanced calcium mobilization in rat ventricular myocytes during the onset of pressure overload-induced hypertrophy. Am J Physiol Heart Circ Physiol 2006, 291:H1803-H1813. 10.1152/ajpheart.01345.2005, 16648178.
33. Diaz ME, Graham HK, Trafford AW. Enhanced sarcolemmal Ca2+ efflux reduces sarcoplasmic reticulum Ca2+ content and systolic Ca2+ in cardiac hypertrophy. Cardiovasc Res 2004, 62:538-547. 10.1016/j.cardiores.2004.01.038, 15158146.
34. Yeung HM, Kravtsov GM, Ng KM, Wong TM, Fung ML. Chronic intermittent hypoxia alters Ca2+ handling in rat cardiomyocytes by augmented Na+/Ca2+ exchange and ryanodine receptor activities in ischemia-reperfusion. Am J Physiol Cell Physiol 2007, 292:C2046-C2056. 10.1152/ajpcell.00458.2006, 17267548.
35. Larsen KO, Sjaastad I, Svindland A, Krobert KA, Skjonsberg OH, Christensen G. Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice. Am J Physiol Heart Circ Physiol 2006, 291:H507-H516. 10.1152/ajpheart.00862.2005, 16582020.
36. Mittmann C, Munstermann U, Weil J, Bohm M, Herzig S, Nienaber C, Eschenhagen T. Analysis of gene expression patterns in small amounts of human ventricular myocardium by a multiplex RNase protection assay. J Mol Med (Berl) 1998, 76:133-140.
37. Bers DM. Cardiac excitation-contraction coupling. Nature 2002, 415:198-205. 10.1038/415198a, 11805843.
38. MacDougall LK, Jones LR, Cohen P. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem 1991, 196:725-734. 10.1111/j.1432-1033.1991.tb15871.x, 1849481.
39. Aoyama H, Ikeda Y, Miyazaki Y, Yoshimura K, Nishino S, Yamamoto T, Yano M, Inui M, Aoki H, Matsuzaki M. Isoform-specific roles of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated Ca(2+) cycling. Cardiovasc Res 2011, 89:79-88. 10.1093/cvr/cvq252, 20675715.
40. Boknik P, Fockenbrock M, Herzig S, Knapp J, Linck B, Luss H, Muller FU, Muller T, Schmitz W, Schroder F, Neumann J. Protein phosphatase activity is increased in a rat model of long-term beta-adrenergic stimulation. Naunyn Schmiedebergs Arch Pharmacol 2000, 362:222-231. 10.1007/s002100000283, 10997724.
41. Dragon S, Offenhauser N, Baumann R. cAMP and in vivo hypoxia induce tob, ifr1, and fos expression in erythroid cells of the chick embryo. Am J Physiol Regul Integr Comp Physiol 2002, 282:R1219-R1226.
42. Dragon S, Carey C, Martin K, Baumann R. Effect of high altitude and in vivo adenosine/(&bgr;)-adrenergic receptor blockade on ATP and 2,3BPG concentrations in red blood cells of avian embryos. J Exp Biol 1999, 202(Pt 20):2787-2795.
43. Vatner DE, Homcy CJ, Sit SP, Manders WT, Vatner SF. Effects of pressure overload, left ventricular hypertrophy on beta-adrenergic receptors, and responsiveness to catecholamines. J Clin Invest 1984, 73:1473-1482. 10.1172/JCI111351, 425170, 6325505.
44. Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, et al. Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol 2002, 22:4124-4135. 10.1128/MCB.22.12.4124-4135.2002, 133876, 12024026.
45. Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res 2005, 96:756-766. 10.1161/01.RES.0000161256.85833.fa, 15746443.