Tumor-conditioned mesenchymal stem cells display hematopoietic differentiation and diminished influx of Ca 2+

Stem Cells and Development

Volumn 21, Issue 9, 2012, Pages 1418-1428

  Zhang, Liyang ^a   Tang, Anliu ^a   Zhou, Yanhong ^a   Tang, Jingqun ^b   Luo, Zhaohui ^a   Jiang, Chen ^a   Li, Xiaoling ^a   Xiang, Juanjuan ^a   Li, Guiyuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CD11B ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; CELL MARKER; CHEMOKINE; LIPOPOLYSACCHARIDE; MONOKINE; NITRIC OXIDE; VERAPAMIL;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CANCER CELL; CELL CONTACT; CELL CULTURE; CELL DIFFERENTIATION; CELL INTERACTION; CELL LINEAGE; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MACROPHAGE; MESENCHYMAL STEM CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; CALCIUM; CELL DIFFERENTIATION; CELL LINE, TUMOR; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MESENCHYMAL STEM CELLS; NEOPLASMS;

EID: 84862194435     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0319     Document Type: Article

References (28)

1. Freisinger E, C Cramer, X Xia, SN Murthy, DP Slakey, E Chiu, ER Newsome, EU Alt and R Izadpanah. (2010). Characterization of hematopoietic potential of mesenchymal stem cells. J Cell Physiol 225:888-897.
2. Barry FP and JM Murphy. (2004). Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 36:568-584. (Pubitemid 38324589)
3. Marion NW and JJ Mao. (2006). Mesenchymal stem cells and tissue engineering. Methods Enzymol 420:339-361. (Pubitemid 44855870)
4. Alvarez-Dolado M, R Pardal, JM Garcia-Verdugo, JR Fike, HO Lee, K Pfeffer, C Lois, SJ Morrison and A Alvarez- Buylla. (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425:968-973. (Pubitemid 37376928)
5. Cousin B, M Andre, E Arnaud, L Penicaud and L Casteilla. (2003). Reconstitution of lethally irradiated mice by cells isolated from adipose tissue. Biochem Biophys Res Commun 301:1016-1022. (Pubitemid 36279214)
6. Xiang J, J Tang, C Song, Z Yang, DG Hirst, QJ Zheng and G Li. (2009). Mesenchymal stem cells as a gene therapy carrier for treatment of fibrosarcoma. Cytotherapy 11:516-526.
7. Song C, J Xiang, J Tang, DG Hirst, J Zhou, KM Chan and G Li. (2011). Thymidine kinase gene modified bone marrow mesenchymal stem cells as vehicles for antitumor therapy. Hum Gene Ther 22:439-449.
8. Quante M, SP Tu, H Tomita, T Gonda, SS Wang, S Takashi, GH Baik, W Shibata, B Diprete, et al. (2011). Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 19:257-272.
9. Kilroy GE, SJ Foster, X Wu, J Ruiz, S Sherwood, A Heifetz, JW Ludlow, DM Stricker, S Potiny, et al. (2007). Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol 212:702-709. (Pubitemid 47271882)
10. Ratajczak J, E Zuba-Surma, I Klich, R Liu, M Wysoczynski, N Greco, M Kucia, MJ Laughlin and MZ Ratajczak. (2011). Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells. Leukemia 25:1278-1275.
11. Nakamura S, T Matsumoto, J Sasaki, H Egusa, KY Lee, T Nakano, T Sohmura and A Nakahira. (2010). Effect of calcium ion concentrations on osteogenic differentiation and hematopoietic stem cell niche-related protein expression in osteoblasts. Tissue Eng Part A 16:2467-2473.
12. Black BL and EN Olson. (1998). Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol 14:167-196. (Pubitemid 29001453)
13. Molkentin JD, L Li and EN Olson. (1996). Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity. J Biol Chem 271:17199-17204. (Pubitemid 26244273)
14. Arnaudeau S, N Holzer, S Konig, CR Bader and L Bernheim. (2006). Calcium sources used by post-natal human myoblasts during initial differentiation. J Cell Physiol 208:435-445. (Pubitemid 43993434)
15. Konig S, A Beguet, CR Bader and L Bernheim. (2006). The calcineurin pathway links hyperpolarization (Kir2.1)- induced Ca2+ signals to human myoblast differentiation and fusion. Development 133:3107-3114. (Pubitemid 44404334)
16. Paez PM, DJ Fulton, V Spreur, V Handley and AT Campagnoni. (2010). Multiple kinase pathways regulate voltage-dependent Ca2+ influx and migration in oligodendrocyte precursor cells. J Neurosci 30:6422-6433.
17. Rittling SR. (2011). Osteopontin in macrophage function. Expert Rev Mol Med 13:e15.
18. Choi KD, J Yu, K Smuga-Otto, G Salvagiotto, W Rehrauer, M Vodyanik, J Thomson and I Slukvin. (2009). Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells 27:559-567.
19. Karlsson KR, S Cowley, FOMartinez,MShaw, SLMinger and W James. (2008). Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. Exp Hematol 36:1167-1175.
20. Jazwiec B, A Solanilla, C Grosset, FX Mahon, M Dupouy, V Pigeonnier-Lagarde, F Belloc, K Schweitzer, J Reiffers and J Ripoche. (1998). Endothelial cell support of hematopoiesis is differentially altered by IL-1 and glucocorticoids. Leukemia 12:1210-1220. (Pubitemid 28395983)
21. Vodyanik MA, JA Bork, JA Thomson and II Slukvin. (2005). Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood 105:617-626. (Pubitemid 40070744)
22. Shi RZ, JC Wang, SH Huang, XJ Wang and QP Li. (2009). Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells. Exp Cell Res 315:10-15.
23. Goldstein RH, MR Reagan, K Anderson, DL Kaplan and M Rosenblatt. (2010). Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res 70:10044-10050.
24. Le Blanc K and O Ringden. (2005). Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol BloodMarrowTransplant 11:321-334. (Pubitemid 40542924)
25. Stagg J and J Galipeau. (2007). Immune plasticity of bone marrow-derived mesenchymal stromal cells. Handb Exp Pharmacol 180:45-66.
26. Le Blanc K, C Tammik, K Rosendahl, E Zetterberg and O Ringden. (2003). HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 31:890-896. (Pubitemid 37211373)
27. Francois M, R Romieu-Mourez, S Stock-Martineau, MN Boivin, JL Bramson and J Galipeau. (2009).Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties. Blood 114:2632-2638.
28. Paez PM, D Fulton, CS Colwell and AT Campagnoni. (2009). Voltage-operated Ca (2+) and Na (+) channels in the oligodendrocyte lineage. J Neurosci Res 87:3259-3266.