Dietary α-linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis

Nutrition

Volumn 28, Issue 7-8, 2012, Pages 799-802

  Ibrahim, Ayman ^a   Aziz, Moutaz ^b   Hassan, Aktham ^a   Mbodji, Khaly ^a   Collasse, Elodie ^b   Coëffier, Moïse ^a,b   Bounoure, Frédéric ^c   Savoye, Guillaume ^a,b   Déchelotte, Pierre ^a,b   Marion Letellier, Rachel ^a  

^a Faculté de Médecine Pharmacie   (France)

^b ROUEN UNIVERSITY HOSPITAL   (France)

^c University of Medicine   (France)

Author keywords

Linolenic acid; 3 Polyunsaturated acids; Adhesion molecules; Colitis; Heme oxygenase 1; Intestine

Indexed keywords

CORN OIL; FISH OIL; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; LINOLENIC ACID; TRINITROBENZENESULFONIC ACID; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOWN REGULATION; ENTERITIS; EXPERIMENTAL MODEL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ALPHA-LINOLENIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRASSICACEAE; CELL ADHESION MOLECULES; COLITIS; COLON; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HEME OXYGENASE-1; INTERCELLULAR ADHESION MOLECULE-1; INTESTINAL MUCOSA; MALE; PLANT OILS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

RATTUS; ZEA MAYS;

EID: 84862193915     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2011.10.008     Document Type: Article

References (23)

1. Danese S. Inflammation and the mucosal microcirculation in inflammatory bowel disease: the ebb and flow. Curr Opin Gastroenterol 2007, 23:384-389.
2. Scaldaferri F., Vetrano S., Sans M., Arena V., Straface G., Stigliano E., et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis. Gastroenterology 2009, 136:585-595. e585.
3. Ghosh S., Panaccione R. Anti-adhesion molecule therapy for inflammatory bowel disease. Therap Adv Gastroenterol 2010, 3:239-258.
4. Ibrahim A., Mbodji K., Hassan A., Boukhettala N., Coëffier M., Savoye G., et al. Anti-inflammatory and anti-angiogenic effect of long chain n-3 polyunsaturated fatty acids in intestinal microvascular endothelium. Clin Nutr 2011, 30:678-687.
5. Marion-Letellier R., Butler M., Dechelotte P., Playford R.J., Ghosh S. Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor gamma ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells-potential for dietary modulation of peroxisome proliferator-activated receptor gamma in intestinal inflammation. Am J Clin Nutr 2008, 87:939-948.
6. Hassan A., Ibrahim A., Mbodji K., Coëffier M., Savoye G., Déchelotte P., et al. An alpha-linolenic acid-rich formula reduces oxidative stress and inflammation by regulating NF-kappaB in rats with TNBS-induced colitis. J Nutr 2010, 140:1714-1721.
7. German A.J., Hall E.J., Day M.J. Analysis of leucocyte subsets in the canine intestine. J Comp Pathol 1999, 120:129-145.
8. Ramakers J.D., Mensink R.P., Schaart G., Plat J. Arachidonic acid but not eicosapentaenoic acid (EPA) and oleic acid activates NF-kappaB and elevates ICAM-1 expression in Caco-2 cells. Lipids 2007, 42:687-698.
9. Rallidis L.S., Paschos G., Papaioannou M.L., Liakos G.K., Panagiotakos D.B., Anastasiadis G., Zampelas A. The effect of diet enriched with [alpha]-linolenic acid on soluble cellular adhesion molecules in dyslipidaemic patients. Atherosclerosis 2004, 174:127-132.
10. Danese S., Sans M., de la Motte C., Graziani C., West G., Phillips M.H., et al. Angiogenesis as a novel component of inflammatory bowel disease pathogenesis. Gastroenterology 2006, 130:2060-2073.
11. Wang D., Wang H., Brown J., Daikoku T., Ning T., Shi O., et al. CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. J Exp Med 2006, 203:941-951.
12. Feagan B.G., Sandborn W.J., Mittmann U., Cohen A., Dallaire C., Ponich T.P., et al. Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC randomized controlled trials. JAMA 2008, 299:1690-1697.
13. De Ley M., de Vos R., Hommes D.W., Stokkers P. Fish oil for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2007, 17:CD005986.
14. Turner D., Shah P.S., Steinhart A.H., Zlotkin S., Griffiths A.M. Maintenance of remission in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analyses. Inflamm Bowel Dis 2011, 17:336-345.
15. Sugawara K., Olson T.S., Moskaluk C.A., Stevens B.K., Hoang S., Kozaiwa K., et al. Linkage to peroxisome proliferator-activated receptor-[gamma] in SAMP1/YitFc mice and in human Crohn's disease. Gastroenterology 2005, 128:351-360.
16. Andersen V., Christensen J., Ernst A., Jacobsen B.A., Tjønneland A.A., Krarup H.B., Vogel U.U. Polymorphisms in NF-kappaB, PXR, LXR, PPARgamma and risk of inflammatory bowel disease. World J Gastroenterol 2011, 17:197-206.
17. Guerreiro C.S., Ferreira P., Tavares L., Santos P.M., Neves M., Brito M., Cravo M. Fatty acids, IL6, and TNFalpha polymorphisms: an example of nutrigenetics in Crohn's disease. Am J Gastroenterol 2009, 104:2241-2249.
18. Ferreira P., Cravo M., Guerreiro C.S., Paula Moura Santos, Manuela Neves, Miguel Brito and Marãlia Cravo Fat intake interacts with polymorphisms of Caspase9, FasLigand and PPARgamma apoptotic genes in modulating Crohn's disease activity. Clin Nutr 2011, 29:819-823.
19. Matsunaga H., Hokari R., Kurihara C., Komoto S., Nakamura M., Tsuzuki Y., Kawaguchi A., et al. Omega-3 polyunsaturated fatty acids ameliorate the severity of ileitis in the senescence accelerated mice (SAM)P1/Yit mice model. Clin Exp Immunol 2009, 158:325-333.
20. Soares M.P., Seldon M.P., Gregoire I.P., Vassilevskaia T.T., Berberat P.O., Yu J.J., et al. Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J Immunol 2004, 172:3553-3563.
21. Marion-Letellier R., Dechelotte P., Iacucci M., Ghosh S. Dietary modulation of peroxisome proliferator-activated receptor gamma. Gut 2009, 58:586-593.
22. Horváth K, Varga C, Berkó A, Pósa AA, Lászlo FF and Whittle BJ. The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis. Eur J Pharmacol 2008;581:315-23.
23. Collins T., Read M.A., Neish A.S., Whitley M., Thanos D., Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 1995, 9:899-909.