Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle

Cellular Reprogramming

Volumn 14, Issue 3, 2012, Pages 235-247

  Sangalli, Juliano Rodrigues ^a   De Bem, Tiago Henrique Camara ^a   Perecin, Felipe ^a   Chiaratti, Marcos Roberto ^a   Oliveira, Lilian De Jesus ^a   De Araújo, Reno Roldi ^a   Valim Pimentel, José Rodrigo ^a   Smith, Lawrence Charles ^b   Meirelles, Flávio Vieira ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; HYDRALAZINE; TRICHOSTATIN A; VALPROIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATTLE; CELL CLONING; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; FIBROBLAST; HISTONE ACETYLATION; NIDATION; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; ZYGOTE;

ACETYLATION; ANIMALS; AZACITIDINE; CATTLE; CELL NUCLEUS; CELLS, CULTURED; CHROMATIN ASSEMBLY AND DISASSEMBLY; CLONING, ORGANISM; EMBRYONIC DEVELOPMENT; FEMALE; HISTONE DEACETYLASE INHIBITORS; HISTONES; HYDRALAZINE; HYDROXAMIC ACIDS; NUCLEAR TRANSFER TECHNIQUES; PREGNANCY; TERM BIRTH; UP-REGULATION; VALPROIC ACID; ZYGOTE;

EID: 84862163929     PISSN: 21524971     EISSN: 21524998     Source Type: Journal    
DOI: 10.1089/cell.2011.0079     Document Type: Article

References (64)

1. Akagi, S., Matsukawa, K., Mizutani, E., et al. (2011). Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos. J. Reprod. Dev. 57, 120-126.
2. Bradner, J.E., West, N., Grachan, M.L., et al. (2010). Chemical phylogenetics of histone deacetylases. Nat. Chem. Biol. 6, 238-243.
3. Chavez-Blanco, A., Perez-Plasencia, C., Perez-Cardenas, E., et al. (2006). Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. Cancer Cell. Int. 6, 2.
4. Chuang, J.C., Yoo, C.B., Kwan, J.M., et al. (2005). Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine. Mol. Cancer Ther. 4, 1515-1520. (Pubitemid 41556433)
5. Cibelli, J. (2007). Developmental biology. A decade of cloning mystique. Science 316, 990-902.
6. Costa-Borges, N., Santalo, J., and Ibanez, E. (2011). Comparison between the effects of valproic acid and trichostatin A on the in vitro development, blastocyst quality, and full-term development of mouse somatic cell nuclear transfer embryos. Cell Reprogram. 12, 437-446.
7. Csoka, A.B., and Szyf, M. (2009). Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology. Med. Hypotheses 73, 770-780.
8. Cui, X.S., Xu, Y.N., Shen, X.H., et al. (2011). Trichostatin a modulates apoptotic-related gene expression and improves embryo viability in cloned bovine embryos. Cell Reprogram. 13, 179-189.
9. Das, Z.C., Gupta, M.K., Uhm, S.J., et al. (2011). Increasing histone acetylation of cloned embryos, but not donor cells, by sodium butyrate improves their in vitro development in pigs. Cell Reprogram. 12, 95-104.
10. De Bem, T.H., Chiaratti, M.R., Rochetti, R., et al. (2011). Viable calves produced by somatic cell nuclear transfer using meiotic-blocked oocytes. Cell Reprogram. 13, 419-429.
11. Dean, W., Santos, F., Stojkovic, M., et al. (2001). Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc. Natl. Acad. Sci. USA 98, 13734-13738. (Pubitemid 33115967)
12. Detich, N., Bovenzi, V., and Szyf, M. (2003). Valproate induces replication-independent active DNA demethylation. J. Biol. Chem. 278, 27586-27592. (Pubitemid 36899944)
13. Ding, X., Wang, Y., Zhang, D., et al. (2008). Increased preimplantation development of cloned bovine embryos treated with 5-aza-2′-deoxycytidine and trichostatin A. Theriogenology 70, 622-630.
14. Enright, B.P., Kubota, C., Yang, X., et al. (2003). Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2′-deoxycytidine. Biol. Reprod. 69, 896-901. (Pubitemid 37064618)
15. Enright, B.P., Sung, L.Y., Chang, C.C., et al. (2005). Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2′-deoxycytidine. Biol. Reprod. 72, 944-948. (Pubitemid 40404270)
16. Fletcher, C.J., Roberts, C.T., Hartwich, K.M., et al. (2007). Somatic cell nuclear transfer in the sheep induces placental defects that likely precede fetal demise. Reproduction 133, 243-255. (Pubitemid 46332172)
17. Giraldo, A.M., Lynn, J.W., Purpera, M.N., et al. (2007). DNA methylation and histone acetylation patterns in cultured bovine fibroblasts for nuclear transfer. Mol. Reprod. Dev. 74, 1514-1524. (Pubitemid 350058417)
18. Gurdon, J.B. (2006). From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation. Annu. Rev. Cell Dev. Biol. 22, 1-22.
19. Gurdon, J.B., and Melton, D.A. (2008). Nuclear reprogramming in cells. Science 322, 1811-1815.
20. Hochedlinger, K., and Jaenisch, R. (2006). Nuclear reprogramming and pluripotency. Nature 441, 1061-1067. (Pubitemid 43990717)
21. Huangfu, D., Maehr, R., Guo, W., et al. (2008). Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 26, 795-797. (Pubitemid 351961456)
22. Hubbert, C., Guardiola, A., Shao, R., et al. (2002). HDAC6 is a microtubule-associated deacetylase. Nature 417, 455-458. (Pubitemid 34563539)
23. Iager, A.E., Ragina, N.P., Ross, P.J., et al. (2008). Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. Cloning Stem Cells 10, 371-379.
24. Jackson-Grusby, L., Beard, C., Possemato, R., et al. (2001). Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat. Genet. 27, 31-39. (Pubitemid 32044515)
25. Jaenisch, R., and Bird, A. (2003). Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33(Suppl.), 245-254. (Pubitemid 36278835)
26. Jeon, B.G., Coppola, G., Perrault, S.D., et al. (2008). Sadenosylhomocysteine treatment of adult female fibroblasts alters X-chromosome inactivation and improves in vitro embryo development after somatic cell nuclear transfer. Reproduction 135, 815-828. (Pubitemid 351837394)
27. Jones, P.L., Veenstra, G.J., Wade, P.A., et al. (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19, 187-191. (Pubitemid 28248804)
28. Kato, Y., Tani, T., and Tsunoda, Y. (2000). Cloning of calves from various somatic cell types of male and female adult, newborn and fetal cows. J. Reprod. Fertil. 120, 231-237.
29. Kelly, T.K., De Carvalho, D.D., and Jones, P.A. (2011). Epigenetic modifications as therapeutic targets. Nat. Biotechnol. 28, 1069-1078.
30. Kishigami, S., Mizutani, E., Ohta, H., et al. (2006). Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. Biochem. Biophys. Res. Commun. 340, 183-189. (Pubitemid 41827663)
31. Kouzarides, T. (2007). Chromatin modifications and their function. Cell 128, 693-705.
32. Kuhholzer, B., Hawley, R.J., Lai, L., et al. (2001). Clonal lines of transgenic fibroblast cells derived from the same fetus result in different development when used for nuclear transfer in pigs. Biol. Reprod. 64, 1695-1698. (Pubitemid 32493486)
33. Lee, M.J., Kim, S.W., Lee, H.G., et al. (2011). Trichostatin a promotes the development of bovine somatic cell nuclear transfer embryos. J. Reprod. Dev. 57, 34-42.
34. Li, J., Svarcova, O., Villemoes, K., et al. (2008). High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. Theriogenology 70, 800-808.
35. Martinez-Diaz, M.A., Che, L., Albornoz, M., et al. (2010). Pre- and postimplantation development of swine-cloned embryos derived from fibroblasts and bone marrow cells after inhibition of histone deacetylases. Cell Reprogram. 12, 85-94.
36. Meirelles, F.V., Birgel, E.H., Perecin, F., et al. (2010). Delivery of cloned offspring: experience in Zebu cattle (Bos indicus). Reprod. Fertil. Dev. 22, 88-97.
37. Meng, Q., Polgar, Z., Liu, J., et al. (2009). Live birth of somatic cell-cloned rabbits following trichostatin A treatment and cotransfer of parthenogenetic embryos. Cloning Stem Cells 11, 203-208.
38. Miyoshi, K., Mori, H., Mizobe, Y., et al. (2010). Valproic acid enhances in vitro development and Oct-3/4 expression of miniature pig somatic cell nuclear transfer embryos. Cell Reprogram. 12, 67-74.
39. Monteiro, F.M., Oliveira, C.S., Oliveira, L.Z., et al. (2011). Chromatin modifying agents in the in vitro production of bovine embryos. Vet. Med. Int.
40. Morgan, H.D., Santos, F., Green, K., et al. (2005). Epigenetic reprogramming in mammals. Hum. Mol. Genet. 14(Spec. No. 1), R47-R58.
41. Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
42. Nasser, L.F., Reis, E.L., Oliveira, M.A., et al. (2004). Comparison of four synchronization protocols for fixed-time bovine embryo transfer in Bos indicus x Bos taurus recipients. Theriogenology 62, 1577-1584. (Pubitemid 39415747)
43. Ono, T., Li, C., Mizutani, E., et al. (2010). Inhibition of class IIb histone deacetylase significantly improves cloning efficiency in mice. Biol. Reprod. 83, 929-937.
44. Pasque, V., Miyamoto, K., and Gurdon, J.B. (2011). Efficiencies and mechanisms of nuclear reprogramming. Cold Spring Harb. Symp. Quant. Biol. 75, 189-200.
45. Schnieke, A.E., Kind, A.J., Ritchie, W.A., et al. (1997). Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science 278, 2130-2133. (Pubitemid 28028324)
46. Segura-Pacheco, B., Perez-Cardenas, E., Taja-Chayeb, L., et al. (2006). Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine. J. Transl. Med. 4, 32.
47. Shi, L.H., Miao, Y.L., Ouyang, Y.C., et al. (2008). Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. Dev. Dyn. 237, 640-648.
48. Singh, N., Duenas-Gonzalez, A., Lyko, F., et al. (2009). Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1. Chem. Med. Chem. 4, 792-799.
49. Song, Y., and Zhang, C. (2009). Hydralazine inhibits human cervical cancer cell growth in vitro in association with APC demethylation and re-expression. Cancer Chemother. Pharmacol. 63, 605-613.
50. Susko-Parrish, J.L., Leibfried-Rutledge, M.L., Northey, D.L., et al. (1994). Inhibition of protein kinases after an induced calcium transient causes transition of bovine oocytes to embryonic cycles without meiotic completion. Dev. Biol. 166, 729-739.
51. Szyf, M. (2009). Epigenetics, DNA methylation, and chromatin modifying drugs. Annu. Rev. Pharmacol. Toxicol. 49, 243-263.
52. Wang, L.J., Zhang, H., Wang, Y.S., et al. (2011a). Scriptaid improves in vitro development and nuclear reprogramming of somatic cell nuclear transfer bovine embryos. Cell Reprogram. 13, 431-439.
53. Wang, Y., Su, J., Wang, L., et al. (2011b). The effects of 5-Aza-2′-deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts. Cell Reprogram. 13, 297-306.
54. Wang, Y.S., Xiong, X.R., An, Z.X., et al. (2011c). Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2′-deoxycytidine and trichostatin A. Theriogenology 75, 819-825.
55. Watanabe, Y.F., Watanabe, M.R., Vila, R.A., et al. (1999). The influence of B2 and a modified CR-2 medium on the in vitro production of bovine embryos with cumulus and oviduct co-culture. Theriogenology 51, 259-259.
56. Wee, G., Koo, D.B., Song, B.S., et al. (2006). Inheritable histone H4 acetylation of somatic chromatins in cloned embryos. J. Biol. Chem. 281, 6048-6057. (Pubitemid 43847706)
57. Wells, D.N. (2005). Animal cloning: problems and prospects. Rev. Sci. Technol. 24, 251-264.
58. Wells, D.N., Oback, B., and Laible, G. (2003). Cloning livestock: a return to embryonic cells. Trends Biotechnol. 21, 428-432.
59. Whitworth, K.M., Zhao, J., Spate, L.D., et al. (2011). Scriptaid corrects gene expression of a few aberrantly reprogrammed transcripts in nuclear transfer pig blastocyst stage embryos. Cell Reprogram. 13, 191-204.
60. Wilmut, I., Schnieke, A.E., McWhir, J., et al. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813. (Pubitemid 27106068)
61. Wilmut, I., Beaujean, N., de Sousa, P.A., et al. (2002). Somatic cell nuclear transfer. Nature 419, 583-586.
62. Yang, X., Smith, S.L., Tian, X.C., et al. (2007). Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning. Nat. Genet. 39, 295-302. (Pubitemid 46328492)
63. Zhao, J., Ross, J.W., Hao, Y., et al. (2009). Significant improvement in cloning efficiency of an inbred miniature pig by histone deacetylase inhibitor treatment after somatic cell nuclear transfer. Biol. Reprod. 81, 525-530.
64. Zhao, J., Hao, Y., Ross, J.W., et al. (2010). Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic cell nuclear transfer porcine embryos. Cell Reprogram. 12, 75-83.