Cannabinoid CB 1 receptor restrains accentuated activity of hypothalamic corticotropin-releasing factor and brainstem tyrosine hydroxylase neurons in endotoxemia-induced hypophagia in rats

Neuropharmacology

Volumn 63, Issue 1, 2012, Pages 154-160

  Rorato, Rodrigo ^a   Reis, Wagner Luis ^a   Carvalho Borges, Beatriz De ^a   Antunes Rodrigues, José ^a   Kagohara Elias, Lucila Leico ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

CB 1 receptor; CRF; Food intake; LPS; TH

Indexed keywords

ALPHA INTERMEDIN; CANNABINOID 1 RECEPTOR; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; MESSENGER RNA; PROTEIN FOS; THYROID HORMONE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN NERVE CELL; BRAIN STEM; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT GENE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; CORTICOTROPIN RELEASING FACTOR GENE; ENDOTOXEMIA; FOOD INTAKE; GENE; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HYPOPHAGIA; HYPOTHALAMUS NUCLEUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANOREXIA NERVOSA; BODY WEIGHT; BRAIN STEM; CELL COUNT; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DISEASE MODELS, ANIMAL; EATING; ENDOTOXEMIA; GENE EXPRESSION REGULATION; HYPOTHALAMUS; LIPOPOLYSACCHARIDES; MALE; MELANOCYTE-STIMULATING HORMONES; MICRODIALYSIS; NEURONS; ONCOGENE PROTEINS V-FOS; PIPERIDINES; PYRAZOLES; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; RNA, MESSENGER; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 84862149768     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.11.009     Document Type: Article

References (60)

1. H.C. Atkinson, J.D. Leggett, S.A. Wood, E.S. Castrique, Y.M. Kershaw, and S.L. Lightman Regulation of the hypothalamic-pituitary-adrenal axis circadian rhythm by endocannabinoids is sexually diergic Endocrinology 151 2010 3720 3727
2. I. Barna, D. Zelena, A.C. Arszovszki, and C. Ledent The role of endogenous cannabinoids in the hypothalamo-pituitary-adrenal axis regulation: in vivo and in vitro studies in CB1 receptor knockout mice Life Sci. 75 2004 2959 2970
3. B.C. Borges, J. Antunes-Rodrigues, M. Castro, J.C. Bittencourt, C.F. Elias, and L.L. Elias Expression of hypothalamic neuropeptides and the desensitization of pituitary-adrenal axis and hypophagia in the endotoxin tolerance Horm. Behav. 52 2007 508 519
4. B.C. Borges, R. Rorato, Y. Avraham, L.E. da Silva, M. Castro, L. Vorobiav, E. Berry, J. Antunes-Rodrigues, and L.L. Elias Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge Am. J. Physiol. Endocrinol. Metab. 300 2011 E858 E869
5. M. Bouaboula, S. Perrachon, L. Milligan, X. Canat, M. Rinaldi-Carmona, M. Portier, F. Barth, B. Calandra, F. Pecceu, J. Lupker, J.P. Maffrand, G. Le Fur, and P. Casellas A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1. Evidence for a new model of receptor/ligand interactions J. Biol. Chem. 272 1997 22330 22339
6. G. Burdyga, S. Lal, A. Varro, R. Dimaline, D.G. Thompson, and G.J. Dockray Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin J. Neurosci 24 2004 2708 2715
7. G. Burdyga, A. Varro, R. Dimaline, D.G. Thompson, and G.J. Dockray Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics, and role in influencing neurochemical phenotype Am. J. Physiol. Gastrointest. Liver Physiol. 299 2010 G63 G69
8. H.E. Chuluyan, D. Saphier, W.M. Rohn, and A.J. Dunn Noradrenergic innervation of the hypothalamus participates in adrenocortical responses to interleukin-1 Neuroendocrinology 56 1992 106 111
9. G. Colombo, R. Agabio, G. Diaz, C. Lobina, R. Reali, and G.L. Gessa Appetite suppression and weight loss after the cannabinoid antagonist SR 141716 Life Sci. 63 1998 PL113 117
10. D. Cota, G. Marsicano, M. Tschöp, Y. Grübler, C. Flachskamm, M. Schubert, D. Auer, A. Yassouridis, C. Thöne-Reineke, S. Ortmann, F. Tomassoni, C. Cervino, E. Nisoli, A.C. Linthorst, R. Pasquali, B. Lutz, G.K. Stalla, and U. Pagotto The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis J. Clin. Invest. 112 2003 423 431
11. D. Cota, M.A. Steiner, G. Marsicano, C. Cervino, J.P. Herman, Y. Grübler, J. Stalla, R. Pasquali, B. Lutz, G.K. Stalla, and U. Pagotto Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function Endocrinology 148 2007 1574 1581
12. R. Dantzer Cytokine-induced sickness behavior: mechanisms and implications Ann. N.Y. Acad. Sci. 933 2001 222 234
13. J.M. Daun, and D.O. McCarthy The role of cholecystokinin in interleukin-1-induced anorexia Physiol. Behav. 54 1993 237 241
14. J.S. Davison, and G.D. Clarke Mechanical properties and sensitivity to CCK of vagal gastric slowly adapting mechanoreceptors Am. J. Physiol. Gastrointest. Liver Physiol. 255 1988 G55 G61
15. C.V. Dayas, K.M. Buller, and T.A. Day Hypothalamic paraventricular nucleus neurons regulate medullary catecholamine cell responses to restraint stress J. Comp. Neurol. 478 2004 22 34
16. L. De Petrocellis, M.G. Cascio, and V. Di Marzo The endocannabinoid system: a general view and latest additions Br. J. Pharmacol. 141 2004 765 774
17. V. Di Marzo, S.K. Goparaju, L. Wang, J. Liu, S. Batkai, Z. Jarai, F. Fezza, G.I. Miura, R.D. Palmiter, T. Sugiura, and G. Kunos Leptin-regulated endocannabinoids are involved in maintaining food intake Nature 410 2001 822 855
18. S. Di, R. Malcher-Lopes, K.C. Halmos, and J.G. Tasker Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism J. Neurosci. 23 2003 4850 4857
19. C. Doyon, R.G. Denis, E.D. Baraboi, P. Samson, J. Lalonde, Y. Deshaies, and D. Richard Effects of rimonabant (SR141716) on fasting-induced hypothalamic-pituitary-adrenal axis and neuronal activation in lean and obese Zucker rats Diabetes 55 2006 3403 3410
20. L.L. Elias, J. Antunes-Rodrigues, P.C. Elias, and A.C. Moreira Effect of plasma osmolality on pituitary-adrenal responses to corticotropin-releasing hormone and atrial natriuretic peptide changes in central diabetes insipidus J. Clin. Endocrinol. Metab. 82 1997 1243 1247
21. D. Engblom, M. Ek, S. Saha, A. Ericsson-Dahlstrand, P.J. Jakobsson, and A. Blomqvist Prostaglandins as inflammatory messengers across the bloo-brain barrier J. Mol. Med. 80 2002 5 15
22. A. Ericsson, K.J. Kovács, and P.E. Sawchenko A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons J. Neurosci. 14 1994 897 913
23. N.K. Evanson, J.G. Tasker, M.N. Hill, C.J. Hillard, and J.P. Herman Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling Endocrinology 151 2010 4811 4819
24. R. Gómez, M. Navarro, B. Ferrer, J.M. Trigo, A. Bilbao, I. Del Arco, A. Cippitelli, F. Nava, D. Piomelli, and F. Rodríguez de Fonseca A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding J. Neurosci. 22 2002 9612 9617
25. R.P. Gaykema, T.E. Daniels, N.J. Shapiro, G.C. Thacker, S.M. Park, and L.E. Goehler Immune challenge and satiety-related activation of both distinct and overlapping neuronal populations in the brainstem indicate parallel pathways for viscerosensory signaling Brain Res. 1294 2009 61 79
26. A.C. Howlett, P.H. Reggio, S.R. Childers, R.E. Hampson, N.M. Ulloa, and D.G. Deutsch Endocannabinoid tone versus constitutive activity of cannabinoid receptors Br. J. Pharmacol. 163 2011 1329 1343
27. L. Jacobson, and R. Sapolsky The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis Endocr. Rev. 12 1991 118 134
28. N. Jamshidi, and D.A. Taylor Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats Br. J. Pharmacol. 134 2001 1151 1154
29. O. Jbilo, C. Ravinet-Trillou, M. Arnone, I. Buisson, E. Bribes, A. Péleraux, G. Pénarier, P. Soubrié, G. Le Fur, S. Galiègue, and P. Casellas The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance FASEB J. 19 2005 1567 1569
30. J. Jelsing, P.J. Larsen, and N. Vrang The effect of leptin receptor deficiency and fasting on cannabinoid receptor 1 mRNA expression in the rat hypothalamus, brainstem and nodose ganglion Neurosci. Lett. 463 2009 125 129
31. T.C. Kirkham, C.M. Williams, F. Fezza, and V. Di Marzo Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol Br. J. Pharmacol. 136 2002 550 557
32. M. Kurosawa, K. Uvnäs-Moberg, K. Miyasaka, and T. Lundeberg Interleukin-1 increases activity of the gastric vagal afferent nerve partly via stimulation of type A CCK receptor in anesthetized rats J. Auton. Nerv. Syst. 62 1997 72 78
33. I. Kushner The acute phase response: an overview Meth. Enzymol. 163 1988 373 383
34. S. Lal, A.J. Kirkup, A.M. Brunsden, D.G. Thompson, and D. Grundy Vagal afferent responses to fatty acids of different chain length in the rat Am. J. Physiol. Gastrointest. Liver. Physiol. 281 2001 G907 G915
35. S.J. MacLennan, P.H. Reynen, J. Kwan, and D.W. Bonhaus Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors Br. J. Pharmacol. 124 1998 619 622
36. P. Mailleux, and J.J. Vanderhaeghen Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry Neuroscience 48 1992 655 668
37. G. Marsicano, and B. Lutz Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain Eur. J. Neurosci. 11 1999 4213 4225
38. D.G. Marsicano, M. Tschop, Y. Grubler, C. Flachskamm, M. Schubert, D. Auer, A. Yassouridis, C. Thone-Reineke, S. Ortmann, F. Tomassoni, C. Cervino, E. Nisoli, A.C. Linthorst, R. Pasquali, B. Lutz, G.K. Stalla, and U. Pagotto The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis J. Clin. Invest. 112 2003 423 431
39. J.E. Morley, A.S. Levine, and N.E. Rowland Minireview: stress-induced eating Life Sci. 32 1983 2169 2182
40. S. Patel, C.T. Roelke, D.J. Rademacher, W.E. Cullinan, and C.J. Hillard Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis Endocrinology 145 2004 5431 5438
41. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 1997 Academic Press San Diego
42. R.G. Pertwee Inverse agonism and neutral antagonism at cannabinoid CB1 receptors Life Sci. 76 2005 1307 1324
43. D. Piomelli The molecular logic of endocannabinoid signalling Nat. Rev. Neurosci. 4 2003 873 884
44. M. Rinaldi-Carmona, F. Barth, M. Héaulme, D. Shire, B. Calandra, C. Congy, S. Martinez, J. Maruani, G. Néliat, and D. Caput SR141716A, a potent and selective antagonist of the brain cannabinoid receptor FEBS Lett. 350 1994 240 244
45. M. Rinaldi-Carmona, F. Barth, M. Héaulme, R. Alonso, D. Shire, C. Congy, P. Soubrié, J.C. Brelière, and G. Le Fur Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist Life Sci. 56 1995 1941 1947
46. L. Rinaman Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation J. Neurosci. 23 2003 10084 10092
47. R.C. Ritter, M. Covasa, and C.A. Matson Cholecystokinin: proofs and prospects for involvement in control of food intake and body weight Neuropeptides 33 1999 387 399
48. M. Roche, M. Diamond, J.P. Kelly, and D.P. Finn In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids J. Neuroimmunol. 181 2006 57 67
49. R. Rorato, M. Castro, B.C. Borges, M. Benedetti, C.M. Germano, J. Antunes-Rodrigues, and L.L. Elias Adrenalectomy enhances endotoxemia-induced hypophagia: higher activation of corticotrophin-releasing-factor and proopiomelanocortin hypothalamic neurons Horm. Behav. 54 2008 134 142
50. R. Rorato, A.M. Menezes, A. Giusti-Paiva, M. de Castro, J. Antunes-Rodrigues, and L.L. Elias Prostaglandin mediates endotoxaemia-induced hypophagia by activation of pro-opiomelanocortin and corticotrophin-releasing factor neurons in rats Exp. Physiol. 94 2009 371 379
51. R. Rorato, W.L. Reis, J. Antunes-Rodrigues, and L.L. Elias Cholecystokinin and hypothalamic corticotrophin-releasing factor participate in endotoxin-induced hypophagia Exp. Physiol. 96 2011 439 450
52. P.E. Sawchenko, and L.W. Swanson Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat J. Comp. Neurol. 205 1982 260 272
53. G.J. Schwartz Integrative capacity of the caudal brainstem in the control of food intake Philos. Trans. R. Soc. Lond. B Biol. Sci. 361 2006 1275 1280
54. A.V. Turnbull, and C.L. Rivier Regulation of the hypothalamic-pituitary- adrenal axis by cytokines: actions and mechanisms of action Physiol. Rev. 79 1999 1 71
55. K. Van Pett, V. Viau, J.C. Bittencourt, R.K. Chan, H.Y. Li, C. Arias, G.S. Prins, M. Perrin, W. Vale, and P.E. Sawchenko Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse J. Comp. Neurol. 428 2000 191 212
56. A.N. Verty, A.M. Allen, and B.J. Oldfield The effects of rimonabant on brown adipose tissue in rat: implications for energy expenditure Obesity (Silver Spring) 17 2009 254 261
57. C.M. Williams, and T.C. Kirkham Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors Psychopharmacology (Berl) 143 1999 315 317
58. C.M. Williams, and T.C. Kirkham Reversal of delta 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine Pharmacol. Biochem. Behav. 71 2002 333 340
59. C.M. Williams, P.J. Rogers, and T.C. Kirkham Hyperphagia in pre-fed rats following oral delta9-THC Physiol. Behav. 65 1998 343 346
60. Y.H. Zhang, J. Lu, J.K. Elmquist, and C.B. Saper Lipopolysaccharide activates specific populations of hypothalamic and brainstem neurons that project to the spinal cord J. Neurosci. 20 2000 6578 6586