Aggravated chronic brain injury after focal cerebral ischemia in aquaporin-4-deficient mice

Neuroscience Letters

Volumn 520, Issue 1, 2012, Pages 121-125

  Shi, Wen Zhen ^a   Qi, Ling Ling ^a   Fang, San Hua ^a   Lu, Yun Bi ^a   Zhang, Wei Ping ^a   Wei, Er Qing ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

AQP4 deficiency; Aquaporin 4 (AQP4); Astrocyte; Chronic brain injury; Focal cerebral ischemia; Glial scar

Indexed keywords

AQUAPORIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ATROPHY; BRAIN INJURY; BRAIN ISCHEMIA; CELL PROLIFERATION; CHRONIC BRAIN INJURY; CONTROLLED STUDY; FOCAL CEREBRAL ISCHEMIA; GLIA; HIPPOCAMPUS; MOUSE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; SCAR FORMATION; SURVIVAL RATE; WEIGHT GAIN;

ANIMALS; AQUAPORIN 4; CELL COUNT; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC DISEASE; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, KNOCKOUT; NEUROGLIA; NEURONS;

EID: 84862125252     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.05.052     Document Type: Article

References (30)

1. Auguste K.I., Jin S., Uchida K., Yan D., Manley G.T., Papadopoulos M.C., Verkman A.S. Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB Journal 2007, 21:108-116.
2. Bush T.G., Puvanachandra N., Horner C.H., Polito A., Ostenfeld T., Svendsen C.N., Mucke L., Johnson M.H., Sofroniew M.V. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 1999, 23:297-308.
3. Dirnagl U., Simon R.P., Hallenbeck J.M. Ischemic tolerance and endogenous neuroprotection. Trends in Neurosciences 2003, 26:248-254.
4. Fan Y., Kong H., Shi X., Sun X., Ding J., Wu J., Hu G. Hypersensitivity of aquaporin 4-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine and astrocytic modulation. Neurobiology of Aging 2008, 29:1226-1236.
5. Faulkner J.R., Herrmann J.E., Woo M.J., Tansey K.E., Doan N.B., Sofroniew M.V. Reactive astrocytes protect tissue and preserve function after spinal cord injury. Journal of Neuroscience 2004, 24:2143-2155.
6. Graber D.J., Levy M., Kerr D., Wade W.F. Neuromyelitis optica pathogenesis and aquaporin 4. Journal of Neuroinflammation 2008, 5:22.
7. Harada S., Fujita W.H., Shichi K., Tokuyama S. The development of glucose intolerance after focal cerebral ischemia participates in subsequent neuronal damage. Brain Research 2009, 1279:174-181.
8. Herrmann J.E., Imura T., Song B., Qi J., Ao Y., Nguyen T.K., Korsak R.A., Takeda K., Akira S., Sofroniew M.V. STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. Journal of Neuroscience 2008, 28:7231-7243.
9. Hinson S.R., McKeon A., Lennon V.A. Neurological autoimmunity targeting aquaporin-4. Neuroscience 2010, 168:1009-1018.
10. Kofler J., Otsuka T., Zhang Z., Noppens R., Grafe M.R., Koh D.W., Dawson V.L., de Murcia J.M., Hurn P.D., Traystman R.J. Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism 2006, 26:135-141.
11. Kuppers E., Gleiser C., Brito V., Wachter B., Pauly T., Hirt B., Grissmer S. AQP4 expression in striatal primary cultures is regulated by dopamine - implications for proliferation of astrocytes. European Journal of Neuroscience 2008, 28:2173-2182.
12. Liedtke W., Edelmann W., Chiu F.C., Kucherlapati R., Raine C.S. Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. American Journal of Pathology 1998, 152:251-259.
13. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
14. Manley G.T., Fujimura M., Ma T., Noshita N., Filiz F., Bollen A.W., Chan P., Verkman A.S. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nature Medicine 2000, 6:159-163.
15. Matsushita T., Isobe N., Matsuoka T., Ishizu T., Kawano Y., Yoshiura T., Ohyagi Y., Kira J. Extensive vasogenic edema of anti-aquaporin-4 antibody-related brain lesions. Multiple Sclerosis 2009, 15:1113-1117.
16. Nesic O., Lee J., Ye Z., Unabia G.C., Rafati D., Hulsebosch C.E., Perez-Polo J.R. Acute and chronic changes in aquaporin 4 expression after spinal cord injury. Neuroscience 2006, 143:779-792.
17. Ohtaki H., Mori S., Nakamachi T., Dohi K., Yin L., Endo S., Okada Y., Shioda S. Evaluation of neuronal cell death after a new global ischemia model in infant mice. Acta Neurochirurgica Supplementum 2003, 86:97-100.
18. Okada S., Nakamura M., Katoh H., Miyao T., Shimazaki T., Ishii K., Yamane J., Yoshimura A., Iwamoto Y., Toyama Y., Okano H. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nature Medicine 2006, 12:829-834.
19. Papadopoulos M.C., Verkman A.S. Aquaporin-4 and brain edema. Pediatric Nephrology 2007, 22:778-784.
20. Pignataro G., Maysami S., Studer F.E., Wilz A., Simon R.P., Boison D. Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism. Journal of Cerebral Blood Flow and Metabolism 2008, 28:17-23.
21. Saadoun S., Papadopoulos M.C. Aquaporin-4 in brain and spinal cord oedema. Neuroscience 2010, 168:1036-1046.
22. Saadoun S., Papadopoulos M.C., Watanabe H., Yan D., Manley G.T., Verkman A.S. Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. Journal of Cell Science 2005, 118:5691-5698.
23. Saikali P., Cayrol R., Vincent T. Anti-aquaporin-4 auto-antibodies orchestrate the pathogenesis in neuromyelitis optica. Autoimmunity Review 2009, 9:132-135.
24. Satoh J., Tabunoki H., Yamamura T., Arima K., Konno H. Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo. Neuropathology 2007, 27:245-256.
25. Shi W.Z., Zhao C.Z., Zhao B., Zheng X.L., Fang S.H., Lu Y.B., Zhang W.P., Chen Z., Wei E.Q. Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain. Neurosci Bull 2012, 28:61-68.
26. 2+ signaling events elicited by cerebral edema. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:846-851.
27. Voskuhl R.R., Peterson R.S., Song B., Ao Y., Morales L.B., Tiwari-Woodruff S., Sofroniew M.V. Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. Journal of Neuroscience 2009, 29:11511-11522.
28. Xu L., Sapolsky R.M., Giffard R.G. Differential sensitivity of murine astrocytes and neurons from different brain regions to injury. Experimental Neurology 2001, 169:416-424.
29. Ye Y.L., Shi W.Z., Zhang W.P., Wang M.L., Zhou Y., Fang S.H., Liu L.Y., Zhang Q., Yu Y.P., Wei E.Q. Cilostazol, a phosphodiesterase 3 inhibitor, protects mice against acute and late ischemic brain injuries. European Journal of Pharmacology 2007, 557:23-31.
30. Yu G.L., Wei E.Q., Wang M.L., Zhang W.P., Zhang S.H., Weng J.Q., Chu L.S., Fang S.H., Zhou Y., Chen Z., Zhang Q., Zhang L.H. Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice. Brain Research 2005, 1053:116-125.