Chitosan microspheres in novel drug delivery systems

Indian Journal of Pharmaceutical Sciences

Volumn 73, Issue 4, 2011, Pages 355-366

  Mitra, Analava ^a   Dey, Baishakhi ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

Author keywords

bio compatible; Biopolymer; chitosan; coacervation; drug targeting; ionotropic gelation; microcapsules; phase separation

Indexed keywords

BOVINE SERUM ALBUMIN; CHITOSAN; CHLORHEXIDINE ACETATE; CLOZAPINE; DICLOFENAC; DIPHTHERIA TOXOID; DOXORUBICIN DERIVATIVE; ERGOCALCIFEROL; GADOLINIUM PENTETATE; INSULIN; LIDOCAINE; PHENOBARBITAL; PREDNISOLONE; PROGESTERONE; RECOMBINANT INTERLEUKIN 2;

COACERVATION; CONTROLLED DRUG RELEASE; CROSS LINKING; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; DRUG RELEASE; EMULSION; ENCAPSULATION; GELATION; HUMAN; MORPHOLOGY; NONHUMAN; PARTICLE SIZE; PHASE SEPARATION; PROSTATE DISEASE; REACTION ANALYSIS; REVERSE MICELLE; REVIEW; SPRAY DRYING; SYNTHESIS;

EID: 84862093957     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.95607     Document Type: Review

References (40)

1. Charman WN, Chan HK, Finnin BC, Charman SA. Drug Delivery: A key factor in realising the full therapeutic potential of drugs. Drug Dev Res 1999;46:316-27.
2. Kopecek J. Smart and genetically engineered biomaterials and drug delivery systems. Eur J Pharm Sci 2003;20:1-16.
3. Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro- and nanoparticles in drug delivery. J Control Release 2004;100:5-28.
4. Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE. Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release 2001;70:1-20.
5. Kurita K. Chemical modification of chitin and Chitosan. In: Muzzarelli RA, Jeuniaux C, Gooday GW, editors. Chitin in Nature and Technology. New York: Plenum; 1986. p. 287-93.
6. Sanford PA. Chitosan: Commercial uses and potential applications. In: Skjak G, Anthonsen T, Sanford P, editors. Chitin and Chitosan - sources, Chemistry, Biochemistry, Physical Properties and Applications. London, UK: Elsevier; 1989. p. 51-69.
7. Kas HS. Chitosan: Properties, preparations and application to microparticulate systems. J Microencapsul 1997;14:689-711.
8. Yao KD, Peng T, Yin YJ, Xu MX. Microcapsules/microspheres related to chitosan. J Macromol Sci 1995;35:155-80.
9. Thanoo BC, Sunny MC, Jayakrishnan A. Cross-linked chitosan microspheres: Preparation and evaluation as a matrix for the controlled release of pharmaceuticals. J Pharm Pharmacol 1992;44:283-6.
10. Shiraishi S, Imai T, Otagiri M. Controlled release of indomethacin by chitosan- polyelectrolyte complex: Optimization and in vivo/in vitro evaluation. J Control Release 1993;25:217-25.
11. Denkbas EB, Seyyal M, Piskin E. 5-Fluorouracil loaded chitosan microspheres for chemoembolization. J. Microencapsul 1998;16:741-9.
12. Jameela SR, Kumary TV, Lal AV, Jayakrishnan A. Progesterone-loaded chitosan microspheres: A long acting biodegradable controlled delivery system. J Control Release 1998;52:17-24.
13. Al-Helw AA, Al-Angary AA, Mahrous GM, Al-Dardari MM. Preparation and evaluation of sustained release cross-linked chitosan microspheres containing phenobarbitone. J Microencapsul 1998;15: 373-82.
14. Orienti I, Aiedeh K, Gianasi E, Ponti C, Zecchi V. Chitosanindomethacin conjugates: Effect of different substituents on the polysaccharide molecule on drug release. Arch Pharm (Weinheim) 1996;329:245-50.
15. Xu Y, Du Y. Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. Int J Pharm 2003;250:215-26.
16. Shu XZ, Zhu KJ. A novel approach to prepare tripolyphosphate/chitosan complex beads for controlled release drug delivery. Int J Pharm 2000;201:51-8.
17. Pan Y, Li Y, Zhao H, Zheng J, Xu H, Wei G, et al. Chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm 2002;249:139-47.
18. Berthod A, Kreuter J. Chitosan microspheres-improved acid stability and change in physicochemical properties by cross-linking. Proc Int Symp Control Release Bioact Mater 1996;23:369-70.
19. Ozbas-Turan S, Akbuga J, Aral C. Controlled release of interleukin-2 from chitosan microspheres. J Pharm Sci 2002;91:124-5.
20. Tokumitsu H, Ichikawa H, Fukumori Y. Chitosan-gadopentetic acid complex nanoparticles for gadolinium neutron capture therapy of cancer: Preparation by novel emulsion-droplet coalescence technique and characterization. Pharm Res 1999;16:1830-5.
21. He P, Davis SS, Illum L. Chitosan microspheres prepared by spray drying. Int J Pharm 1999;187:53-65.
22. Conti B, Modena T, Genta I, Perugini P, Decarro C, Pavanetto F. Microencapsulation of cetylpyridinium chloride with a bioadhesive polymer. Proc Int Symp Control Release Bioact Mater 1998;25:822-3.
23. Ganza-Gonzalez A, Anguiano-Igea S, Otero-Espinar FJ, Mendez JB. Chitosan and chondroitin microspheres for oral-administration controlled release of metoclopramide. Eur J Pharm Biopharm 1999;48:149-55.
24. Lorenzo-Lamosa ML, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Design of microencapsulated chitosan micro- spheres for colonic drug delivery. J Control Release 1998;52:109-18.
25. Huang YC, Yeh MK, Chiang CH. Formulation factors in preparing BTM-chitosan microspheres by spray drying method. Int J Pharm 2002;242:239-42.
26. Mitra S, Gaur U, Ghosh PC, Maitra AN. Tumor targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. J Control Release 2001;74:317-23.
27. Agnihotri SA, Aminabhavi TM. Controlled release of clozapine through chitosan microparticles prepared by a novel method. J Control Release 2004;96:245-59.
28. Dubey RR, Parikh JR, Parikh RR. Effect of heating temperature and time on pharmaceutical characteristics of albumin microspheres containing 5-fluorouracil. AAPS PharmSciTech 2003;4:E4.
29. Shukla PG, Kalidhass B, Shah A, Palashkar DV. Preparation and characterization of microcapsules of water soluble pesticide monocrotophs using polyurethane as carrier material. J Microencapsul 2002;19:293-304.
30. Nam YS, Park TG. Protein loaded biodegradable microspheres based on PLGA-protein biconjugates. J Microencapsul 1999;16:625-37.
31. Kweon DK, Kang DW. Drug-release behavior of chitosan- g-poly(vinyl alcohol) copolymer matrix. J Appl Polym Sci 1999;74:458-64.
32. Higuchi T. Mechanism of sustained action medication. J Pharm Sci 1963;52:1145-9.
33. Park HS, Lee JY, Cho SH, Baek HJ, Lee SJ. Colon delivery of prednisolone based on chitosan-coated polysaccharide tablets. Arch Pharm Res 2002;25:964-8.
34. Tozaki H, Odoriba T, Okada N, Fujita T, Terabe A, Suzuki T, et al. Chitosan capsules for colon-specific drug delivery: Enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats. J Control Release 2002;82:51-61.
35. Thanou M, Verhoef JC, Marbach P, Junginger HE. Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo. J Pharm Sci 2000;89:951-7.
36. Genta I, Conti B, Perugini P, Pavanetto F, Spadaro A, Puglisi G. Bio-adhesive microspheres for opthalmic administration of acyclovir. J Pharm Pharmacol 1997;49:737-42.
37. Aiedeh K, Taha MO. Synthesis of chitosan succinate and chitosan phthalate and their evaluation as suggested matrices in orally administered, colon-specific drug delivery systems. Arch Pharm (Weinheim) 1999;332:103-7.
38. Robinson JR. Rationale of bioadhesion/mucoadhesion, In: Gurny R, Junginger HE, editors. Bioadhesion: Possibilities and future Trends. Stuttgart, Germany: Wisseschaftliche; 1990. p. 13-5.
39. Lee KY, Kwon IC, Kim YH, Jo WH, Jeong SY. Chitosan conjugated DNA nanoparticles in gene therapy. J Control Release 1998;51:213-20.
40. MacLughlin FC, Mumper RJ, Wang J, Tagliaferri JM, Gill I, Hinchcliffe M, et al. Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: Strategies to improve transfection efficacy. J Control Release 1998;56:259-72.