Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake

Neuropharmacology

Volumn 63, Issue 3, 2012, Pages 415-426

  Nasrabady, Sara Ebrahimi ^a   Kuzhandaivel, Anujaianthi ^a,e   Akrami, Athena ^a   Bianchetti, Elena ^a   Milanese, Marco ^b   Bonanno, Giambattista ^b,c   Nistri, Andrea ^a,d  

^a SISSA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Center of Excellence for Biomedical Research (CEBR)   (Italy)

^d Istituto di Medicina Fisica e Riabilitazione   (Italy)

^e LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Excitotoxicity; Fictive locomotion; Motoneurons

Indexed keywords

4 AMINOBUTYRIC ACID; 6(5H)PHENANTHRIDINONE; GLUTAMIC ACID; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GLIA; IN VITRO STUDY; LOCOMOTION; LUMBAR SPINAL CORD; NERVE CELL MEMBRANE POTENTIAL; NERVE EXCITABILITY; NEUROPROTECTION; NEUROTRANSMITTER UPTAKE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SYNAPTOSOME; VENTRAL ROOT;

AMINO ACIDS; ANIMALS; ANIMALS, NEWBORN; ASPARTIC ACID; CELL COUNT; ELECTROPHYSIOLOGICAL PHENOMENA; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; LOCOMOTION; LUMBOSACRAL REGION; NERVE NET; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR; REFLEX; SPINAL CORD; SYNAPTIC TRANSMISSION;

EID: 84862022770     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.04.014     Document Type: Article

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