메뉴 건너뛰기




Volumn 287, Issue 24, 2012, Pages 20154-20163

GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins

Author keywords

[No Author keywords available]

Indexed keywords

ACID RECEPTORS; BICISTRONIC; CDNA ENDS; CELL TYPES; G PROTEIN COUPLED RECEPTORS; INTERGENIC REGIONS; INTERNAL RIBOSOME ENTRY SITE; LONG CHAIN FATTY ACID; PANCREATIC BETA CELLS; REPORTER-GENE EXPRESSION; SEQUENCE ORGANIZATION; SHORT-CHAIN FATTY ACIDS; TRANSCRIPTIONAL CONTROL; TRANSCRIPTIONAL INITIATION;

EID: 84862005991     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.358887     Document Type: Article
Times cited : (39)

References (40)
  • 3
    • 0035491791 scopus 로고    scopus 로고
    • Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set?
    • Halban, P. A., Kahn, S. E., Lernmark, A., and Rhodes, C. J. (2001) Gene and cell replacement therapy in the treatment of type 1 diabetes. How high must the standards be set? Diabetes 50, 2181-2191 (Pubitemid 33641899)
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2181-2191
    • Halban, P.A.1    Kahn, S.E.2    Lernmark, A.3    Rhodes, C.J.4
  • 5
    • 0142093526 scopus 로고    scopus 로고
    • Fatty acid metabolism and insulin secretion in pancreatic beta cells
    • DOI 10.1007/s00125-003-1207-4
    • Yaney, G. C., and Corkey, B. E. (2003) Fatty acid metabolism and insulin secretion in pancreatic beta cells. Diabetologia 46, 1297-1312 (Pubitemid 37297198)
    • (2003) Diabetologia , vol.46 , Issue.10 , pp. 1297-1312
    • Yaney, G.C.1    Corkey, B.E.2
  • 6
    • 0036323681 scopus 로고    scopus 로고
    • Effects of free fatty acids on insulin secretion in obesity
    • DOI 10.1046/j.1467-789X.2002.00062.x
    • Zraika, S., Dunlop, M., Proietto, J., and Andrikopoulos, S. (2002) Effects of free fatty acids on insulin secretion in obesity. Obes. Rev. 3, 103-112 (Pubitemid 34827151)
    • (2002) Obesity Reviews , vol.3 , Issue.2 , pp. 103-112
    • Zraika, S.1    Dunlop, M.2    Proietto, J.3    Andrikopoulos, S.4
  • 9
    • 52749098923 scopus 로고    scopus 로고
    • Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion
    • Edfalk, S., Steneberg, P., and Edlund, H. (2008) Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes 57, 2280-2287
    • (2008) Diabetes , vol.57 , pp. 2280-2287
    • Edfalk, S.1    Steneberg, P.2    Edlund, H.3
  • 11
    • 20944433543 scopus 로고    scopus 로고
    • The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
    • DOI 10.1016/j.cmet.2005.03.007, PII S1550413105000860
    • Steneberg, P., Rubins, N., Bartoov-Shifman, R., Walker, M. D., and Edlund, H. (2005) The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab. 1, 245-258 (Pubitemid 43960613)
    • (2005) Cell Metabolism , vol.1 , Issue.4 , pp. 245-258
    • Steneberg, P.1    Rubins, N.2    Bartoov-Shifman, R.3    Walker, M.D.4    Edlund, H.5
  • 12
    • 34047177401 scopus 로고    scopus 로고
    • GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo
    • DOI 10.2337/db06-1532
    • Latour, M. G., Alquier, T., Oseid, E., Tremblay, C., Jetton, T. L., Luo, J., Lin, D. C., and Poitout, V. (2007) GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes 56, 1087-1094 (Pubitemid 46525064)
    • (2007) Diabetes , vol.56 , Issue.4 , pp. 1087-1094
    • Latour, M.G.1    Alquier, T.2    Oseid, E.3    Tremblay, C.4    Jetton, T.L.5    Luo, J.6    Lin, D.C.-H.7    Poitout, V.8
  • 13
    • 0031581088 scopus 로고    scopus 로고
    • A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1
    • DOI 10.1006/bbrc.1997.7513
    • Sawzdargo, M., George, S. R., Nguyen, T., Xu, S., Kolakowski, L. F., and O'Dowd, B. F. (1997) A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. Biochem. Biophys. Res. Commun. 239, 543-547 (Pubitemid 27489000)
    • (1997) Biochemical and Biophysical Research Communications , vol.239 , Issue.2 , pp. 543-547
    • Sawzdargo, M.1    George, S.R.2    Nguyen, T.3    Xu, S.4    Kolakowski Jr., L.F.5    O'dowd, B.F.6
  • 15
    • 0023276469 scopus 로고
    • Short chain fatty acids in human large intestine, portal, hepatic and venous blood
    • Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P., and Macfarlane, G. T. (1987) Short chain fatty acids in human large intestine, portal, hepatic, and venous blood. Gut 28, 1221-1227 (Pubitemid 17156038)
    • (1987) Gut , vol.28 , Issue.10 , pp. 1221-1227
    • Cummings, J.H.1    Pomare, E.W.2    Branch, W.J.3    Naylor, C.P.E.4    Macfarlane, G.T.5
  • 16
    • 0025321505 scopus 로고
    • Energy contributions of volatile fatty acids from the gastrointestinal tract in various species
    • Bergman, E. N. (1990) Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol. Rev. 70, 567-590
    • (1990) Physiol. Rev. , vol.70 , pp. 567-590
    • Bergman, E.N.1
  • 21
    • 34548170247 scopus 로고    scopus 로고
    • Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic beta Cells
    • DOI 10.1074/jbc.M702115200
    • Bartoov-Shifman, R., Ridner, G., Bahar, K., Rubins, N., and Walker, M. D. (2007) Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic beta cells. J. Biol. Chem. 282, 23561-23571 (Pubitemid 47311899)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.32 , pp. 23561-23571
    • Bartoov-Shifman, R.1    Ridner, G.2    Bahar, K.3    Rubins, N.4    Walker, M.D.5
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real time quantitative PCR and the 2(-ΔΔC(T)) method. Methods 25, 402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 75549091325 scopus 로고    scopus 로고
    • A protocol for islet isolation from mouse pancreas
    • Li, D. S., Yuan, Y. H., Tu, H. J., Liang, Q. L., and Dai, L. J. (2009) A protocol for islet isolation from mouse pancreas. Nat. Protoc. 4, 1649-1652
    • (2009) Nat. Protoc. , vol.4 , pp. 1649-1652
    • Li, D.S.1    Yuan, Y.H.2    Tu, H.J.3    Liang, Q.L.4    Dai, L.J.5
  • 25
    • 84862025869 scopus 로고    scopus 로고
    • The structures of nonprotein-coding RNAs that drive internal ribosome entry site function
    • Plank, T. D., and Kieft, J. S. (2012) The structures of nonprotein-coding RNAs that drive internal ribosome entry site function. Wiley Interdiscip. Rev. RNA 3, 195-212
    • (2012) Wiley Interdiscip. Rev. RNA , vol.3 , pp. 195-212
    • Plank, T.D.1    Kieft, J.S.2
  • 27
    • 0037600601 scopus 로고    scopus 로고
    • Transcription factors direct the development and function of pancreatic beta cells
    • DOI 10.1016/S1043-2760(02)00039-5, PII S1043276002000395
    • Chakrabarti, S. K., and Mirmira, R. G. (2003) Transcription factors direct the development and function of pancreatic beta cells. Trends Endocrinol. Metab. 14, 78-84 (Pubitemid 36733920)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.2 , pp. 78-84
    • Chakrabarti, S.K.1    Mirmira, R.G.2
  • 29
    • 0021071029 scopus 로고
    • Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes
    • Walker, M. D., Edlund, T., Boulet, A. M., and Rutter, W. J. (1983) Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes. Nature 306, 557-561 (Pubitemid 14203819)
    • (1983) Nature , vol.306 , Issue.5943 , pp. 557-561
    • Walker, M.D.1    Edlund, T.2    Boulet, A.M.3    Rutter, W.J.4
  • 30
    • 0035854774 scopus 로고    scopus 로고
    • Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation
    • Kimura, M., Mizukami, Y., Miura, T., Fujimoto, K., Kobayashi, S., and Matsuzaki, M. (2001) Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation. J. Biol. Chem. 276, 26453-26460
    • (2001) J. Biol. Chem. , vol.276 , pp. 26453-26460
    • Kimura, M.1    Mizukami, Y.2    Miura, T.3    Fujimoto, K.4    Kobayashi, S.5    Matsuzaki, M.6
  • 31
    • 33646376658 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
    • DOI 10.1007/s00441-005-0140-x
    • Karaki, S., Mitsui, R., Hayashi, H., Kato, I., Sugiya, H., Iwanaga, T., Furness, J. B., and Kuwahara, A. (2006) Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res. 324, 353-360 (Pubitemid 43673476)
    • (2006) Cell and Tissue Research , vol.324 , Issue.3 , pp. 353-360
    • Karaki, S.-I.1    Mitsui, R.2    Hayashi, H.3    Kato, I.4    Sugiya, H.5    Iwanaga, T.6    Furness, J.B.7    Kuwahara, A.8
  • 33
    • 59049108244 scopus 로고    scopus 로고
    • A rat brain bicistronic gene with an internal ribosome entry site codes for a phencyclidine-binding protein with cytotoxic activity
    • Hui, D., Kumar, K. N., Mach, J. R., Srinivasan, A., Pal, R., Bao, X., Agbas, A., Höfner, G., Wanner, K. T., and Michaelis, E. K. (2009) A rat brain bicistronic gene with an internal ribosome entry site codes for a phencyclidine-binding protein with cytotoxic activity. J. Biol. Chem. 284, 2245-2257
    • (2009) J. Biol. Chem. , vol.284 , pp. 2245-2257
    • Hui, D.1    Kumar, K.N.2    Mach, J.R.3    Srinivasan, A.4    Pal, R.5    Bao, X.6    Agbas, A.7    Höfner, G.8    Wanner, K.T.9    Michaelis, E.K.10
  • 34
    • 54249116230 scopus 로고
    • Genetic regulatory mechanisms in the synthesis of proteins
    • Jacob, F., and Monod, J. (1961) Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3, 318-356
    • (1961) J. Mol. Biol. , vol.3 , pp. 318-356
    • Jacob, F.1    Monod, J.2
  • 35
    • 0024546509 scopus 로고
    • The scanning model for translocation. An update
    • Kozak, M. (1989) The scanning model for translocation. An update. J. Cell Biol. 108, 229-241
    • (1989) J. Cell Biol. , vol.108 , pp. 229-241
    • Kozak, M.1
  • 36
    • 0033061571 scopus 로고    scopus 로고
    • Initiation of translation in prokaryotes and eukaryotes
    • Kozak, M. (1999) Initiation of translation in prokaryotes and eukaryotes. Gene 234, 187-208
    • (1999) Gene , vol.234 , pp. 187-208
    • Kozak, M.1
  • 37
    • 0023758546 scopus 로고
    • A segment of the 5′-nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
    • Jang, S. K., Kräusslich, H. G., Nicklin, M. J., Duke, G. M., Palmenberg, A. C., and Wimmer, E. (1988) A segment of the 5′-nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol. 62, 2636-2643
    • (1988) J. Virol. , vol.62 , pp. 2636-2643
    • Jang, S.K.1    Kräusslich, H.G.2    Nicklin, M.J.3    Duke, G.M.4    Palmenberg, A.C.5    Wimmer, E.6
  • 38
    • 0023720048 scopus 로고
    • Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
    • Pelletier, J., and Sonenberg, N. (1988) Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334, 320-325
    • (1988) Nature , vol.334 , pp. 320-325
    • Pelletier, J.1    Sonenberg, N.2
  • 39
    • 36749042932 scopus 로고    scopus 로고
    • Mathews, M., Sonenberg, N., and Hershey, J. W. B., eds Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Elroy-Stein, O., and Merrick, W. C. (2007) in Translational Control in Biology and Medicine (Mathews, M., Sonenberg, N., and Hershey, J. W. B., eds) pp. 155-172, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • (2007) Translational Control in Biology and Medicine , pp. 155-172
    • Elroy-Stein, O.1    Merrick, W.C.2
  • 40
    • 0035396727 scopus 로고    scopus 로고
    • Internal ribosome entry sites in eukaryotic mRNA molecules
    • DOI 10.1101/gad.891101
    • Hellen, C. U., and Sarnow, P. (2001) Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev. 15, 1593-1612 (Pubitemid 32702581)
    • (2001) Genes and Development , vol.15 , Issue.13 , pp. 1593-1612
    • Hellen, C.U.T.1    Sarnow, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.