Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in Cicatricial Alopecia

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Panicker, Sreejith P ^a   Ganguly, Taneeta ^a   Consolo, Mary ^a   Price, Vera ^a   Mirmirani, Paradi ^a   Honda, Kord ^a   Karnik, Pratima ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 DEHYDROCHOLESTEROL; CHOLESTEROL; INTERFERON; STEROL; TOLL LIKE RECEPTOR;

ALOPECIA; ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIMARY CICATRICIAL ALOPECIA; SKIN; STEROL SYNTHESIS;

ADOLESCENT; ADULT; ALOPECIA; ANIMALS; BIOSYNTHETIC PATHWAYS; CELLS, CULTURED; CHEMOKINES; CHOLESTEROL; CICATRIX; DEHYDROCHOLESTEROLS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HAIR; HAIR FOLLICLE; HUMANS; IMMUNITY, INNATE; MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PIPERAZINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEROLS;

EID: 84862001937     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038449     Document Type: Article

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