Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABAA receptor subunit expression and anxiety-like behavior

Pharmacology Biochemistry and Behavior

Volumn 102, Issue 2, 2012, Pages 366-372

  Porcu, Patrizia ^a   Mostallino, Maria Cristina ^a   Sogliano, Cristiana ^b   Santoru, Francesca ^b   Berretti, Roberta ^b   Concas, Alessandra ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Allopregnanolone; Anxiety behavior; Female rat; GABAA receptor; Levonorgestrel

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; ETHINYLESTRADIOL; LEVONORGESTREL; PREGNENOLONE; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; LONG TERM CARE; MAZE TEST; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT DURATION;

ANIMALS; ANXIETY; BLOTTING, WESTERN; CEREBRAL CORTEX; ETHINYL ESTRADIOL; FEMALE; HIPPOCAMPUS; LEVONORGESTREL; MAZE LEARNING; PREGNANOLONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

RATTUS;

EID: 84861997721     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2012.05.011     Document Type: Article

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