Diffuse reflectance spectral imaging for breast tumor margin assessment

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 8214, Issue , 2012, Pages

  Lo, Justin Y ^a   Dhar, Sulochana ^a   Yu, Bing ^a   Brooke, Martin A ^a   Kuech, Thomas F ^b   Jokerst, Nan M ^a   Ramanujam, Nimmi ^a  

^a Duke University   (United States)

^b University of Wisconsin Madison   (United States)

Author keywords

Breast cancer; Diffuse reflectance; Margin assessment; Tissue optics

Indexed keywords

BREAST CANCER; BREAST TUMOR; BROADBAND SOURCES; DIFFUSE REFLECTANCE; DIFFUSE REFLECTANCE SPECTROSCOPY; HUMAN TISSUES; IMAGING ARRAYS; MARGIN ASSESSMENT; PROOF OF CONCEPT; SPECTRAL IMAGING; SPECTRAL IMAGING SYSTEM; SYSTEM PROTOTYPE; TISSUE COMPOSITION; TISSUE MIMICKING PHANTOM; TISSUE OPTIC; VISUAL MAP; WIDE-FIELD;

ANIMALS; PIXELS; RATING; REFLECTION; TUMORS;

MEDICAL IMAGING;

EID: 84861928000     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.909259     Document Type: Conference Paper

References (11)

1. Lee, M. C., Rogers, K., Griffith, K., Diehl, K. A., Breslin, T. M., Cimmino, V. M., Chang, A. E., Newman, L. A., and Sabel, M. S., "Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center," The Breast Journal 15, 34-40 (2009).
2. Jacobs, L., "Positive margins: the challenge continues for breast surgeons," Annals of Surgical Oncology 15, 1271-1272 (2008).
3. Bydlon, T. M., Kennedy, S. A., Richards, L. M., Brown, J. Q., Yu, B., Junker, M. K., Gallagher, J. G., Geradts, J., Wilke, L. G., and Ramanujam, N., "Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins," Opt. Exp. 18(8), 8058-8076 (2010).
4. Wilke, L. G., Brown, J. Q., Bydlon, T. M., Kennedy, S. A., Richards, L. M., Junker, M. K., Gallagher, J. G., Barry, W. T., Geradts, J., and Ramanujam, N., "Rapid noninvasive optical imaging of tissue composition in breast tumor margins," Am. J. Surg. 198(4), 566-574 (2009).
5. Lo, J. Y., Yu, B., Kuech, T. F., and Ramanujam, N. "A compact, cost-effective diffuse reflectance spectroscopic imaging system for quantitative tissue absorption and scattering," Proceedings of SPIE Vol. 7890, 78900B (2011).
6. Fu, H. L., Yu, B., Lo, J. Y., Palmer, G. M., Kuech, T. F., and Ramanujam, N., "A low-cost, portable, and quantitative spectral imaging system for application to biological tissues," Opt. Exp. 18(12), 12630-12645 (2010).
7. Dhar, S., Lo, J. Y., Yu, B., Brooke, M. A., Ramanaujam, N., and Jokerst, N. M., "Custom annular photodetector arrays for breast cancer margin assessment using diffuse reflectance spectroscopy," IEEE Biomedical Circuits and Systems Conference, 440-443 (2001).
8. Palmer, G. M., and Ramanujam, N., "Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms," Appl. Opt. 45, 1062-1071 (2006).
9. Yu, B., Lo, J. Y., Palmer, G. M., Bender, J. E., Kuech, T. F., and Ramanujam, N., "A cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo," J. Biomed. Opt. 13(6), 060505 (2008).
10. Lo, J. Y., Yu, B., Fu, H. L., Palmer, G. M., Kuech, T. F., and Ramanujam, N., "A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes," Opt. Exp. 17(3), 1372-1384 (2009).
11. Bender, J. E., Vishwanath, K., Moore, L. K., Brown, J. Q., Chang, V., Palmer, G. M., and Ramanujam, N., "A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo," IEEE Trans. Biomed. Eng. 56(4), 960-968 (2009).