Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo

Journal of Biomedical Optics

Volumn 13, Issue 6, 2008, Pages

  Yu, Bing ^a   Lo, Justin Y ^a   Kuech, Thomas F ^b   Palmer, Gregory M ^c   Bender, Janelle E ^a   Ramanujam, Nirmala ^a  

^a Duke University   (United States)

^b University of Wisconsin Madison   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diffuse reflectance spectroscopy; Spectral imaging

Indexed keywords

DIFFUSE REFLECTANCE SPECTROSCOPY; HIGH SENSITIVITY; IN-VIVO; INVERSE MONTE CARLO; LIGHT COLLECTION EFFICIENCY; SCATTERING CO-EFFICIENT; SPECTRAL IMAGING; SPECTRAL IMAGING SYSTEM; TISSUE ABSORPTION; TISSUE OPTICAL PROPERTIES; TISSUE SURFACE;

ABSORPTION; COST EFFECTIVENESS; DETECTORS; LIGHT SOURCES; MULTIMODE FIBERS; OPTICAL PROPERTIES; PHOTOMAPPING; REFLECTION; SCATTERING; TISSUE;

ABSORPTION SPECTROSCOPY;

ARTICLE; COMPUTER AIDED DESIGN; COMPUTER ASSISTED DIAGNOSIS; ECONOMICS; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; ILLUMINATION; IMAGE QUALITY; INSTRUMENTATION; LIGHT; METHODOLOGY; PHOTOMETRY; RADIATION SCATTERING; RADIOMETRY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY; TRANSDUCER; UNITED STATES;

COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LIGHT; LIGHTING; NEPHELOMETRY AND TURBIDIMETRY; PHANTOMS, IMAGING; PHOTOMETRY; RADIOMETRY; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS; TRANSDUCERS; UNITED STATES;

EID: 62449230776     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3041500     Document Type: Article

References (11)

1. I. J. Bigio and S. G. Bown, "Spectroscopic sensing of cancer and cancer therapy, current status of translational research", Cancer Biother 3(3), 259-267 (2004). (Pubitemid 41350877)
2. G. Zonios, L. T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, and M. S. Feld, "Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo", Appl. Opt. 38(31), 6628-6637 (1999). (Pubitemid 129567570)
3. Y. N. Mirabal, S. K. Chang, E. N. Atkinson, A. Malpica, M. Follen, and R. Richards-Kortum, "Reflectance spectroscopy for in vivo detection of cervical precancer", J. Biomed. Opt. 7(4), 587-594 (2002). (Pubitemid 35459940)
4. W. C. Lin, S. A. Toms, M. Johnson, E. D. Jansen, and A. Mahadevan-Jansen, "In vivo brain tumor demarcation using optical spectroscopy", Photochem. Photobiol. 73(4), 396-402 (2001).
5. C. Zhu, G. M. Palmer, T. M. Breslin, F. Xu, and N. Ramanujam, "Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer", J. Biomed. Opt. 10(2), 024032 (2005).
6. G. M. Palmer and N. Ramanujam, "Monte Carlo-based inverse model for calculating tissue optical properties. Part I, Theory and validation on synthetic phantoms", Appl. Opt. 45(5), 1062-1071 (2006).
7. C. Zhu, G. M. Palmer, T. M. Breslin, J. Harter, and N. Ramanujam, "Diagnosis of breast cancer using diffuse reflectance spectroscopy: comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique", Lasers Surg. Med. 38(7), 714-724 (2006). (Pubitemid 44300946)
8. A. Cerussi, N. Shah, D. Hsiang, A. Durkin, J. Butler, and B. J. Tromberg, "In vivo absorption, scattering, and physiologic properties of 58 malignant breast tumors determined by broadband diffuse optical spectroscopy", J. Biomed. Opt. 11(4), 044005 (2006).
9. J. W. Feather, D. J. Ellis, and G. Leslie, "A portable reflectometer for the rapid quantification of cutaneous haemoglobin and melanin", Phys. Med. Biol. 33(6), 711-722 (1988).
10. J. E. Bender, K. Vishwanath, L. K. Moore, J. Q. Brown, V. Chang, G. M. Palmer, and N. Ramanujam, "A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo", IEEE Trans. Biomed. Eng. (in press).
11. B. C. F. Huffman, Absorption and Scattering of Light by Small Particles, Wiley, New York (1998).