Med5(Nut1) and Med17(Srb4) are direct targets of mediator histone H4 tail interactions

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Liu, Zhongle ^a   Myers, Lawrence C ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BINDING PROTEIN; HISTONE H4; PROTEIN NUT1; PROTEIN SRB4; UNCLASSIFIED DRUG; HISTONE; MEDIATOR COMPLEX; NUT1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SRB4 PROTEIN, S CEREVISIAE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; CONTROLLED STUDY; FUNGAL STRAIN; FUNGUS MUTANT; NONHUMAN; NUCLEOSOME; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET RADIATION; WILD TYPE; GENETICS; HETEROCHROMATIN; METABOLISM; PHYSIOLOGY;

HETEROCHROMATIN; HISTONES; MEDIATOR COMPLEX; NUCLEOSOMES; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84861905985     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038416     Document Type: Article

References (46)

1. Conaway RC, Conaway JW, (2011) Function and regulation of the Mediator complex. Curr Opin Genet Dev 21: 225-230.
2. Myers LC, Kornberg RD, (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69: 729-749.
3. Guglielmi B, van Berkum NL, Klapholz B, Bijma T, Boube M, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32: 5379-5391.
4. Linder T, Gustafsson CM, (2004) The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator. J Biol Chem 279: 49455-49459.
5. Bjorklund S, Gustafsson CM, (2005) The yeast Mediator complex and its regulation. Trends Biochem Sci 30: 240-244.
6. Chadick JZ, Asturias FJ, (2005) Structure of eukaryotic Mediator complexes. Trends Biochem Sci 30: 264-271.
7. Borggrefe T, Davis R, Erdjument-Bromage H, Tempst P, Kornberg RD, (2002) A complex of the Srb8,-9,-10, and-11 transcriptional regulatory proteins from yeast. J Biol Chem 277: 44202-44207.
8. Samuelsen CO, Baraznenok V, Khorosjutina O, Spahr H, Kieselbach T, et al. (2003) TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Proc Natl Acad Sci U S A 100: 6422-6427.
9. Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, et al. (2004) A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Mol Cell 14: 685-691.
10. Conaway RC, Sato S, Tomomori-Sato C, Yao T, Conaway JW, (2005) The mammalian Mediator complex and its role in transcriptional regulation. Trends Biochem Sci 30: 250-255.
11. Bourbon HM, (2008) Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic Acids Res 36: 3993-4008.
12. van de Peppel J, Kettelarij N, van Bakel H, Kockelkorn TT, van Leenen D, et al, (2005) Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets. Mol Cell 19: 511-522.
13. Holstege FC, Jennings EG, Wyrick JJ, Lee TI, Hengartner CJ, et al. (1998) Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95: 717-728.
14. Jiang YW, Dohrmann PR, Stillman DJ, (1995) Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation. Genetics 140: 47-54.
15. Song W, Treich I, Qian N, Kuchin S, Carlson M, (1996) SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II. Mol Cell Biol 16: 115-120.
16. Yu Y, Eriksson P, Stillman DJ, (2000) Architectural transcription factors and the SAGA complex function in parallel pathways to activate transcription. Mol Cell Biol 20: 2350-2357.
17. Howard SC, Chang YW, Budovskaya YV, Herman PK, (2001) The Ras/PKA signaling pathway of Saccharomyces cerevisiae exhibits a functional interaction with the Sin4p complex of the RNA polymerase II holoenzyme. Genetics 159: 77-89.
18. Wang X, Michels CA, (2004) Mutations in SIN4 and RGR1 cause constitutive expression of MAL structural genes in Saccharomyces cerevisiae. Genetics 168: 747-757.
19. Li L, Quinton T, Miles S, Breeden LL, (2005) Genetic interactions between mediator and the late G1-specific transcription factor Swi6 in Saccharomyces cerevisiae. Genetics 171: 477-488.
20. Singh H, Erkine AM, Kremer SB, Duttweiler HM, Davis DA, et al. (2006) A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression. Genetics 172: 2169-2184.
21. Zhu X, Liu B, Carlsten JO, Beve J, Nystrom T, et al. (2011) Mediator influences telomeric silencing and cellular life span. Mol Cell Biol 31: 2413-2421.
22. Zhu X, Zhang Y, Bjornsdottir G, Liu Z, Quan A, et al. (2011) Histone modifications influence mediator interactions with chromatin. Nucleic Acids Res 39: 8342-8354.
23. Andrau JC, van de Pasch L, Lijnzaad P, Bijma T, Koerkamp MG, et al. (2006) Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA. Mol Cell 22: 179-192.
24. Zhu X, Wiren M, Sinha I, Rasmussen NN, Linder T, et al. (2006) Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions. Mol Cell 22: 169-178.
25. Peng J, Zhou JQ, (2012) The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance. Nucleic Acids Res 40: 581-593.
26. Lorch Y, Beve J, Gustafsson CM, Myers LC, Kornberg RD, (2000) Mediator-nucleosome interaction. Mol Cell 6: 197-201.
27. Braunstein M, Sobel RE, Allis CD, Turner BM, Broach JR, (1996) Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol Cell Biol 16: 4349-4356.
28. de Bruin D, Kantrow SM, Liberatore RA, Zakian VA, (2000) Telomere folding is required for the stable maintenance of telomere position effects in yeast. Mol Cell Biol 20: 7991-8000.
29. Dorman G, Prestwich GD, (1994) Benzophenone photophores in biochemistry. Biochemistry 33: 5661-5673.
30. Beve J, Hu GZ, Myers LC, Balciunas D, Werngren O, et al. (2005) The structural and functional role of Med5 in the yeast Mediator tail module. J Biol Chem 280: 41366-41372.
31. Myers LC, Gustafsson CM, Bushnell DA, Lui M, Erdjument-Bromage H, et al. (1998) The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev 12: 45-54.
32. Li Y, Bjorklund S, Jiang YW, Kim YJ, Lane WS, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92: 10864-10868.
33. Lee YC, Park JM, Min S, Han SJ, Kim YJ, (1999) An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol 19: 2967-2976.
34. Macatee T, Jiang YW, Stillman DJ, Roth SY, (1997) Global alterations in chromatin accessibility associated with loss of SIN4 function. Nucleic Acids Res 25: 1240-1247.
35. Jiang YW, Stillman DJ, (1996) Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus. Genes Dev 10: 604-619.
36. Myers LC, Gustafsson CM, Hayashibara KC, Brown PO, Kornberg RD, (1999) Mediator protein mutations that selectively abolish activated transcription. Proc Natl Acad Sci U S A 96: 67-72.
37. Han SJ, Lee JS, Kang JS, Kim YJ, (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276: 37020-37026.
38. Kim YJ, Bjorklund S, Li Y, Sayre MH, Kornberg RD, (1994) A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599-608.
39. Thompson CM, Koleske AJ, Chao DM, Young RA, (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73: 1361-1375.
40. Imasaki T, Calero G, Cai G, Tsai KL, Yamada K, et al. (2011) Architecture of the Mediator head module. Nature 475: 240-243.
41. Poux AN, Marmorstein R, (2003) Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. Biochemistry 42: 14366-14374.
42. Rani PG, Ranish JA, Hahn S, (2004) RNA polymerase II (Pol II)-TFIIF and Pol II-mediator complexes: the major stable Pol II complexes and their activity in transcription initiation and reinitiation. Mol Cell Biol 24: 1709-1720.
43. Longtine MS, McKenzie A, 3rd, Demarini DJ, Shah NG, Wach A, et al. (1998) Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953-961.
44. Baidoobonso SM, Guidi BW, Myers LC, (2007) Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex. J Biol Chem 282: 5551-5559.
45. Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, et al. (1999) Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285: 901-906.
46. Myers LC, Leuther K, Bushnell DA, Gustafsson CM, Kornberg RD, (1997) Yeast RNA polymerase II transcription reconstituted with purified proteins. Methods 12: 212-216.