The role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii

Parasites and Vectors

Volumn 5, Issue 1, 2012, Pages

  Siddiqui, Ruqaiyyah ^a   Iqbal, Junaid ^a   Maugueret, Marie Josée ^b   Khan, Naveed Ahmed ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Acanthamoeba; Encephalitis; Pathogenesis; Src kinase

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; PROTEIN TYROSINE KINASE; PYRAZOLOPYRIMIDINE DERIVATIVE;

ACANTHAMOEBA CASTELLANII; ARTICLE; BACTERIAL GROWTH; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ASSAY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROVASCULAR ENDOTHELIAL CELL; MOLECULAR PATHOLOGY; NONHUMAN; ZYMOGRAPHY;

ACANTHAMOEBA CASTELLANII; AMINO ACID SEQUENCE; ENDOTHELIAL CELLS; ESCHERICHIA COLI K12; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MOLECULAR SEQUENCE DATA; PHAGOCYTOSIS; PYRIMIDINES; SRC-FAMILY KINASES;

ACANTHAMOEBA; ACANTHAMOEBA CASTELLANII; ESCHERICHIA COLI;

EID: 84861905925     PISSN: None     EISSN: 17563305     Source Type: Journal    
DOI: 10.1186/1756-3305-5-112     Document Type: Article

References (34)

1. Identification and distribution ofAcanthamoebaspecies genotypes associated with nonkeratitis infections. Booton GC, Visvesvara GS, Byers TJ, Kelly DJ, Fuerst PA, J Clin Microbiol 2005 43 1689 1693 10.1128/JCM.43.4.1689- 1693.2005 15814986
2. Phylogenetic evidence for a new genotype ofAcanthamoeba(Amoebozoa, Acanthamoebida). Corsaro D, Venditti D, Parasitol Res 2010 107 233 238 10.1007/s00436-010-1870-6 20411277
3. Identification of a novel t17 genotype ofAcanthamoebafrom environmental isolates and t10 genotype causing keratitis in Thailand. Nuprasert W, Putaporntip C, Pariyakanok L, Jongwutiwes S, J Clin Microbiol 2010 48 4636 4640 10.1128/JCM.01090-10 20943863
4. Biology and Pathogenesis ofAcanthamoeba. Siddiqui R, Khan NA, Parasit Vectors 2012 5 6 10.1186/1756-3305-5-6 22229971
5. Acanthamoebaspp. as agents of disease in humans. Marciano-Cabral F, Cabral G, Clin Microbiol Rev 2003 16 273 307 10.1128/CMR.16.2.273-307.2003 12692099
6. Pathogenic and opportunistic free-living amoebae:Acanthamoebaspp., Balamuthia mandrillaris,Naegleria fowleri, andSappinia diploidea. Visvesvara GS, Moura H, Schuster FL, FEMS Immunol Med Microbiol 2007 50 1 26 10.1111/j.1574-695X.2007.00232.x 17428307
7. Antiprotozoal activities of phospholipid analogues. Croft SL, Seifert K, Duchêne M, Mol Biochem Parasitol 2003 126 165 172 10.1016/S0166-6851(02) 00283-9 12615315
8. Free-living, amphizoic and opportunistic amebas. Martinez AJ, Visvesvara GS, Brain Pathol 1997 7 583 598 10.1111/j.1750-3639.1997.tb01076.x 9034567
9. Acanthamoebaand the blood-brain barrier: the breakthrough. Khan NA, J Med Microbiol 2008 57 1051 1057 10.1099/jmm.0.2008/000976-0 18719172
10. Src redox regulation: there is more than meets the eye. Chiarugi P, Mol. Cell 2008 26 329 337
11. Src protein-tyrosine kinase structure and regulation. Roskoski R, Biochem Biophys Res Commun 2004 324 1155 1164 10.1016/j.bbrc.2004.09.171 15504335
12. Kinases of the Src Family: structure and functions. Tatosyan AG, Mizenina OA, Biochem 2000 65 49 58
13. Acanthamoebaaffects the integrity of the human brain microvascular endothelial cells and degrades the tight junction proteins. Khan NA, Siddiqui R, Int J Parasitol 2009 39 1611 1616 10.1016/j.ijpara.2009.06.004 19580812
14. Selective expression of adhesion molecules on human brain microvascular endothelial cells. Stins MF, Gilles F, Kim KS, J Neuroimmunol 1997 76 81 90 10.1016/S0165-5728(97)00036-2 9184636
15. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. Hanke JH, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ, Pollok BA, Connelly PA, J Biol Chem 1996 271 695 701 10.1074/jbc.271.2.695 8557675
16. Integrin-mediated host cell invasion by type 1-piliated uropathogenicEscherichia coli. Eto DS, Jones TA, Sundsbak JL, Mulvey MA, PLoS Pathog 2007 3 100 10.1371/journal.ppat.0030100 17630833
17. Use ofin vitroassays to determine effects of human serum on biological characteristics ofAcanthamoeba castellanii. Sissons J, Alsam S, Stins M, Rivas AO, Morales JL, Faull J, Khan NA, J Clin Microbiol 2006 44 2595 2600 10.1128/JCM.00144-06 16825391
18. Balamuthia mandrillarisexhibits metalloprotease activities. Matin A, Stins M, Kim KS, Khan NA, FEMS Immunol Med Microbiol 2006 47 83 91 10.1111/j.1574-695X.2006.00065.x 16706791
19. Acanthamoeba castellaniiinduces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism. Sissons J, Kim KS, Stins M, Jayasekera S, Alsam S, Khan NA, Infect Immun 2005 73 2704 2708 10.1128/IAI.73.5.2704-2708.2005 15845472
20. Characterization of pp 60c-src tyrosine kinase activities using a continuous assay: autoactivation of the enzyme is an intermolecular autophosphorylation process. Barker SC, Kassel DB, Weigl D, Huang X, Luther MA, Knight WB, Biochem 1995 34 14843 14851 10.1021/bi00045a027
21. Structure and regulation of Src family kinases. Boggon TJ, Eck MJ, Oncogene 2004 23 7918 7927 10.1038/sj.onc.1208081 15489910
22. Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. Li W, Young SL, King N, Miller WT, J Biol Chem 2008 283 15491 15501 10.1074/jbc.M800002200 18390552
23. Structures of Src-family tyrosine kinases. Sicheri F, Kuriyan J, Curr Opin Struct Biol 1997 7 777 785 10.1016/S0959-440X(97)80146-7 9434895
24. Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors. Zhu X, Kim JL, Newcomb JR, Rose PE, Stover DR, Toledo LM, Zhao H, Morgenstern KA, Structure 1999 7 651 661 10.1016/S0969-2126(99)80086-0 10404594
25. Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor. Kassenbrock CK, Hunter S, Garl P, Johnson GL, Anderson SM, J Biol Chem 2002 277 24967 24975 10.1074/jbc.M201026200 11994282
26. C-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway. Jin W, Yun C, Jeong J, Park Y, Lee HD, Kim SJ, J Biol Chem 2008 283 1391 1400 17991742
27. Src activation regulates anoikis in human colon tumor cell lines. Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE, Oncogene 2002 21 7797 7807 10.1038/sj.onc.1205989 12420216
28. Integrin-mediated invasion ofStaphylococcus aureusinto human cells requires Src family protein-tyrosine kinases. Agerer F, Michel A, Ohlsen K, Hauck CR, J Biol Chem 2003 278 42524 42531 10.1074/jbc.M302096200 12893831
29. The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization duringShigellainvasion of epithelial cells. Mounier J, Popoff MR, Enninga J, Frame MC, Sansonetti PJ, Van Nhieu GT, PLoS Pathog 2009 5 1000271 10.1371/journal.ppat.1000271 19165331
30. Role of carbohydrate-mediated adherence in cytopathogenic mechanisms ofAcanthamoeba. Cao Z, Jefferson DM, Panjwani N, J Biol Chem 1998 273 15838 15845 10.1074/jbc.273.25.15838 9624184
31. In vivoandin vitrocollagenolytic activity ofAcanthamoeba castellanii. He YG, Niederkorn JY, McCulley JP, Stewart GL, Meyer DR, Silvany R, Dougherty J, Invest Ophthalmol Vis Sci 1990 31 2235 2240 2173683
32. Extracellular proteases ofAcanthamoeba castellanii(encephalitis isolate belonging to T1 genotype) contribute to increased permeability in anin vitromodel of the human blood-brain barrier. Alsam S, Sissons J, Jayasekera S, Khan NA, J Infect 2005 51 150 156 10.1016/j.jinf.2004.09.001 16038767
33. Acanthamoebainteractions with human brain microvascular endothelial cells. Alsam S, Kim KS, Stins M, Rivas AO, Sissons J, Khan NA, Microb Pathogen 2003 35 235 241 10.1016/j.micpath.2003.07.001
34. Cloning and characterization of a novel mannose-binding protein ofAcanthamoeba. Garate M, Cao Z, Bateman E, Panjwani N, J Biol Chem 2004 279 29849 29856 10.1074/jbc.M402334200 15117936