Acanthamoeba and the blood-brain barrier: The breakthrough

Journal of Medical Microbiology

Volumn 57, Issue 9, 2008, Pages 1051-1057

  Khan, Naveed Ahmed ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACANTHAMOEBA; BLOOD BRAIN BARRIER; ENCEPHALITIS; GRANULOMATOUS INFLAMMATION; HUMAN; IMMUNOPATHOGENESIS; NEUROLOGICAL COMPLICATION; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTOZOAL INFECTION; RARE DISEASE; REVIEW;

ACANTHAMOEBA; AMEBIASIS; ANIMALS; BLOOD-BRAIN BARRIER; ENCEPHALITIS; HUMANS;

EID: 51149103973     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.2008/000976-0     Document Type: Review

References (39)

1. Alsam, S., Kim, K. S., Stins, M., Rivas, A. O., Sissons, J. & Khan, N. A. (2003). Acanthamoeba interactions with human brain microvascular endothelial cells. Microb Pathog 35, 235-241.
2. Alsam, S., Sissons, J., Dudley, R. & Khan, N. A. (2005a). Mechanisms associated with Acanthamoeba castellanii (T4) phagocytosis. Parasitol Res 96, 402-409.
3. Alsam, S., Sissons, J., Jayasekera, S. & Khan, N. A. (2005b). Extracellular proteases of Acanthamoeba castellanii (encephalitis isolate belonging to T1 genotype) contribute to increased permeability in an in vitro model of the human blood-brain barrier. J Infect 51, 150-156.
4. Benedetto, N. & Auriault, C. (2002a). Prolactin-cytokine network in defence against Acanthamoeba castellanii in murine microglia. Eur Cytokine Netw 13, 447-455.
5. Benedetto, N. & Auriault, C. (2002b). Complex network of cytokines activating murine microglial cell activity against Acanthamoeba castellanii. Eur Cytokine Netw 13, 351-357.
6. Benedetto, N., Rossano, F., Gorga, F., Folgore, A., Rao, M. & Carratelli, C. R. (2003). Defense mechanisms of IFN-γ and LPS-primed murine microglia against Acanthamoeba castellanii infection. Int Immunopharmacol 3, 825-834.
7. Cerva, L. (1967). Intranasal, intrapulmonary and intracardial inoculation of experimental animals with Hartmanella castellanii. Folia Parasitol (Praha) 14, 207-215.
8. Culbertson, C. G., Smith, J. W., Cohen, H. K. & Minner, J. R. (1959). Experimental infection of mice and monkeys by Acanthamoeba. Am J Pathol 35, 185-197.
9. Garate, M., Cao, Z., Bateman, E. & Panjwani, N. (2004). Cloning and characterization of a novel mannose-binding protein of Acanthamoeba. J Biol Chem 279, 29849-29856.
10. Graff, C. L. & Pollack, G. M. (2005). Nasal drug administration: potential for targeted central nervous system delivery. J Pharm Sci 94, 1187-1195.
11. Huber, J. D., Egleton, R. D. & Davis, T. P. (2001). Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier. Trends Neurosci 24, 719-725.
12. Illum, L. (2000). Transport of drugs from the nasal cavity to the central nervous system. Eur J Pharm Sci 11, 1-18.
13. Jinga, V. V., Gafencu, A., Antohe, F., Constantinescu, E., Heltianu, C., Raicu, M., Manolescu, I., Hunziker, W. & Simionescu, M. (2000). Establishment of a pure vascular endothelial cell line from human placenta. Placenta 21, 325-336.
14. Khan, N. A. (2001). Pathogenicity, morphology and differentiation of Acanthamoeba. Curr Microbiol 43, 391-395.
15. Khan, N. A. (2006). Acanthamoeba: biology and increasing importance in human health. FEMS Microbiol Rev 30, 564-595.
16. Khan, N. A. (2007). Acanthamoeba invasion of the central nervous system. Int J Parasitol 37, 131-138.
17. Kim, J. H., Kim, J. H., Park, J. A., Lee, S., Kim, W. J., Yu, Y. S. & Kim, K. (2006). Blood-neural barrier: intercellular communication at gliovascular interface. J Biochem Mol Biol 39, 339-345.
18. Kong, H. H., Kim, T. H. & Chung, D. I. (2000). Purification and characterization of a secretory proteinase of Acanthamoeba healyi isolates from GAE. J Parasitol 86, 12-17.
19. Marciano-Cabral, F. & Cabral, G. (2003). Acanthamoeba spp. as agents of disease in humans. Clin Microbiol Rev 16, 273-307.
20. Marciano-Cabral, F., Puffenbarger, R. & Cabral, G. A. (2000). The increasing importance of Acanthamoeba infections. J Eukaryot Microbiol 47, 29-36.
21. Marciano-Cabral, F., Ludwick, C., Puffenbarger, R. A. & Cabral, G. A. (2004). Differential stimulation of microglial pro-inflammatory cytokines by Acanthamoeba culbertsoni versus Acanthamoeba castellanii. J Eukaryot Microbiol 51, 472-479.
22. Martinez, A. J. (1985). Free-living Amebas: Natural History, Prevention, Diagnosis, Pathology and Treatment of Disease. Boca Raton, FL: CRC Press.
23. Martinez, A. J. (1991). Infections of the central nervous system due to Acanthamoeba. Rev Infect Dis 13, S399-S402.
24. Martinez, A. J. & Visvesvara, G. S. (1997). Free-living, amphizoic and opportunistic amebas. Brain Pathol 7, 583-598.
25. Martinez, A. J., Markowitz, S. M. & Duma, R. J. (1975). Experimental pneumonitis and encephalitis caused by Acanthamoeba in mice: pathogenesis and ultrastructural features. J Infect Dis 131, 692-699.
26. Mattana, A., Cappai, V., Alberti, L., Serra, C., Fiori, P. L. & Cappuccinelli, P. (2002). ADP and other metabolites released from Acanthamoeba castellanii lead to human monocytic cell death through apoptosis and stimulate the secretion of proinflammatory cytokines. Infect Immun 70, 4424-4432.
27. Miller, D. W. (1999). Immunobiology of the blood-brain barrier. J Neurovirol 5, 570-578.
28. Pardridge, W. M. (1999). Blood-brain barrier: biology and methodology. J Neurovirol 5, 556-569.
29. Pardridge, W. M. (2002). Drug and gene delivery to the brain: the vascular route. Neuron 36, 555-558.
30. Petry, F., Torzewski, M., Bohl, J., Wilhelm-Schwenkmezger, T., Scheid, P., Walochnik, J., Michel, R., Zöller, L., Werhahn, K. J. & other authors (2006). Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid. J Clin Microbiol 44, 1903-1904.
31. Pettit, D. A., Williamson, J., Cabral, G. A. & Marciano-Cabral, F. (1996). In vitro destruction of nerve cell cultures by Acanthamoeba spp.: a transmission and scanning electron microscopy study. J Parasitol 82, 769-777.
32. Shen, L., Black, E. D., Witkowski, E. D., Lencer, W. I., Guerriero, V., Schneeberger, E. E. & Turner, J. R. (2006). Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci 119, 2095-2106.
33. Shin, H. J., Cho, M. S., Jung, S. Y., Kim, H. I., Park, S., Seo, J. H., Yoo, J. C. & Im, K. I. (2001). Cytopathic changes in rat microglial cells induced by pathogenic Acanthamoeba culbertsoni: morphology and cytokine release. Clin Diagn Lab Immunol 8, 837-840.
34. Sissons, J., Alsam, S., Jayasekera, S., Kim, K. S., Stins, M. & Khan, N. A. (2004). Acanthamoeba induces cell-cycle arrest in the host cells. J Med Microbiol 53, 711-717.
35. Sissons, J., Kim, K. S., Stins, M., Jayasekera, S., Alsam, S. & Khan, N. A. (2005). Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism. Infect Immun 73, 2704-2708.
36. Sissons, J., Alsam, S., Goldsworthy, G., Lightfoot, M., Jarroll, E. L. & Khan, N. A. (2006). Identification and properties of proteases from an Acanthamoeba isolate capable of producing granulomatous encephalitis. BMC Microbiol 6, 42.
37. Stins, M. F., Gilles, F. & Kim, K. S. (1997). Selective expression of adhesion molecules on human brain microvascular endothelial cells. J Neuroimmunol 76, 81-90.
38. Tuomanen, E. (1996). Entry of pathogens into the central nervous system. FEMS Microbiol Rev 18, 289-299.
39. Visvesvara, G. S., Moura, H. & Schuster, F. L. (2007). Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 50, 1-26.