Continuous crystallization of Aliskiren hemifumarate

Crystal Growth and Design

Volumn 12, Issue 6, 2012, Pages 3036-3044

  Quon, Justin L ^a   Zhang, Haitao ^a   Alvarez, Alejandro ^b   Evans, James ^a   Myerson, Allan S ^a   Trout, Bernhardt L ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE INGREDIENTS; COMPLEX ORGANIC MOLECULES; CONTINUOUS CRYSTALLIZATION; CRYSTAL PURITY; CRYSTAL SHAPES; EQUILIBRIUM DISTRIBUTION COEFFICIENT; EXPERIMENTAL DATA; HIGH PURITY; HIGH YIELD; KINETIC EXPRESSION; MASS BALANCE; MIXED SUSPENSION MIXED PRODUCT REMOVALS; OPERATING CONDITION; OPERATING TEMPERATURE; PHARMACEUTICAL PRODUCTS; POPULATION BALANCE EQUATION; PROCESS DEVELOPMENT; PROCESS YIELD; REACTIVE CRYSTALLIZATION; RESIDENCE TIME; SIMULTANEOUS SOLUTION;

DRUG PRODUCTS; NUCLEATION; POLYMORPHISM;

CRYSTAL GROWTH;

EID: 84861903353     PISSN: 15287483     EISSN: 15287505     Source Type: Journal    
DOI: 10.1021/cg300253a     Document Type: Article

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