Expression of NOS and VEGF in feline mammary tumours and their correlation with angiogenesis

Veterinary Journal

Volumn 192, Issue 3, 2012, Pages 338-344

  Islam, M S ^a   Matsumoto, M ^a   Hidaka, R ^a   Miyoshi, N ^a   Yasuda, N ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Feline mammary tumours; Immunohistochemistry; INOS; Tumour grade; VEGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; VASCULOTROPIN;

ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GRADING; CAT; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LOCALIZATION; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR PROMOTION; TUMOR VASCULARIZATION;

ANIMALS; CAT DISEASES; CATS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; MAMMARY NEOPLASMS, ANIMAL; NEOVASCULARIZATION, PATHOLOGIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

FELIDAE;

EID: 84861875297     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2011.08.032     Document Type: Article

References (48)

1. Aaltoma S.H., Lipponen P.K., Kosma V.M. Inducible nitric oxide synthase (i-NOS) expression and its prognostic value in prostate cancer. Anticancer Research 2001, 21:3101-3106.
2. Ambs S., Merriam W.G., Ogunfusika M.O., Bennett W.P., Ishibe N., Hussain S.P., Tzeng E.E., Geller D.A., Billiar T.R., Harris C.C. p53 and vascular endothelial growth factor regulate tumour growth of NOS2-expressing human carcinoma cells. Nature Medicine 1998, 4:1371-1376.
3. Anggard E. Nitric oxide: Mediator, murderer, and medicine. Lancet 1994, 343:1199-1206.
4. Bulut A.S., Erden E., Sak S.D., Doruk H., Kursun N., Dincol D. Significance of inducible nitric oxide synthase in benign and malignant breast epithelium: An immunohistochemical study of 151 cases. Virchows Archiv 2005, 447:24-30.
5. Cianchi F., Cortesini C., Fantappiè O., Messerini L., Schiavone N., Vannacci A., Nistri S., Sardi I., Baroni G., Marzocca C., Perna F., Mazzanti R., Bechi P., Masini E. Inducible nitric oxide synthase expression in human colorectal cancer. American Journal of Pathology 2003, 162:793-801.
6. De-Wever O., Mareei M. Role of tissue stroma in cancer cell invasion. Journal of Pathology 2003, 200:429-447.
7. Ellies L.G., Fishman M., Hardison J., Kleeman J., Maglione J.E., Manner C.K., Cardiff R.D., MacLeod C.L. Mammary tumour latency is increased in mice lacking the inducible nitric oxide synthase. International Journal of Cancer 2003, 106:1-7.
8. Elston C.W., Ellis I.O. Assessment of histological grade. Systemic Pathology - The Breast 1998, 365-384. Churchill and Livingstone, London, UK. Third Ed. C.W. Elston, I.O. Ellis (Eds.).
9. Ferrara N., Gerber H.P., LeCouter J. The biology of VEGF and its receptors. Nature Medicine 2003, 9:669-676.
10. Folkman J., Shing Y. Angiogenesis. Journal of Biological Chemistry 1992, 267:10931-10934.
11. Forstermann U., Closs E.I., Pollock J.S., Nakane M., Schwarz P., Gath I., Kleinert H. Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994, 23:1121-1131.
12. Forsythe J.A., Jiang B.H., Iyer N.V., Agani F., Leung S.W., Koos R.D., Semenza G.L. Activation of vascular endothelial growth factor gene transcription by a hypoxia-induced factor. Molecular and Cellular Biology 1996, 16:4604-4613.
13. Fukumura D., Kashiwagi S., Jain R.K. The role of nitric oxide in tumour progression. Nature Reviews Cancer 2006, 6:521-534.
14. Gallo O., Masini E., Morbidelli L., Franchi A., Fini-Storchi I., Vergari W.A., Ziche M. Role of nitric oxide in angiogenesis and tumour progression in head and neck cancer. Journal of the National Cancer Institute 1998, 90:587-596.
15. Giménez F., Hecht S., Craig L.E., Legendre A.M. Early detection, aggressive therapy: optimizing the management of feline mammary masses. Journal of Feline Medicine and Surgery 2010, 12:214-224.
16. Horak E.R., Leek R., Klenk N., LeJeune S., Smith K., Stuart N., Greenall M., Stepniewska K., Harris A.L. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 1992, 340:1120-1124.
17. Islam M.S., Matsumoto M., Tsuchida K., Oka T., Kanouchi H., Suzuki S. Immunohistochemical localization of nitric oxide synthase (NOS) in mouse mammary gland during reproductive cycle. Journal of Veterinary Medical Science 2009, 71:945-949.
18. Islam M.S., Matsumoto M., Ishida R., Oka T., Kanouchi H. Change in VEGF Expression in mouse mammary gland during reproductive cycle. Journal of Veterinary Medical Science 2010, 72:1159-1163.
19. Jadeski L.C., Chakraborty C., Lala P.K. Role of nitric oxide in tumour progression with special reference to a murine breast cancer model. Canadian Journal of Physiology and Pharmacology 2002, 80:125-135.
20. Jenkins D.C., Charles I.G., Thomsen L.L., Moss D.W., Holmes L.S., Baylis S.A., Rhodes P., Westmore K., Emson P.C., Moncada S. Role of nitric oxide in tumour growth. Proceedings of the National Academy of Sciences of United States of America 1995, 92:4392-4396.
21. Kimura H., Esumi H. Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochimica Polonica 2003, 50:49-59.
22. Lacasse P., Farr V.C., Davis S.R., Prosser C.G. Local secretion of nitric oxide and the control of mammary blood flow. Journal of Dairy Science 1996, 79:1369-1374.
23. Lala P.K., Chakrabarty C. Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncology 2001, 2:149-156.
24. Loibl S., von Minckwitz G., Weber S., Sinn H.P., Schini-Kerth V.B., Lobysheva I., Nepveu F., Wolf G., Strebhardt K., Kaufmann M. Expression of endothelial and inducible nitric oxide synthase in benign and malignant lesions of the breast and measurement of nitric oxide using electron paramagnetic resonance spectroscopy. Cancer 2002, 95:1191-1198.
25. Loibl S., Buck A., Strank C., von Minckwitz G., Roller M., Sinn H.P., Schini-Kerth V., Solbach C., Strebhardt K., Kaufmann M. The role of early expression of inducible nitric oxide synthase in human breast cancer. European Journal of Cancer 2005, 41:265-271.
26. Martin L., Green B., Renshaw C., Lowe D., Rudland P., Leinster S.J., Winstanley J. Examining the technique of angiogenesis assessment in invasive breast cancer. British Journal of Cancer 1997, 76:1046-1054.
27. Martin J.H., Begum S., Alalami O., Harrison A., Scott K.W. Endothelial nitric oxide synthase: Correlation with histologic grade, lymph node status and estrogen receptor expression in human breast cancer. Tumour Biology 2000, 21:90-97.
28. Melillo G., Musso T., Sica A., Taylor L.S., Cox G.W., Varesio L. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. Journal of Experimental Medicine 1995, 182:1683-1693.
29. Millanta F., Lazzeri G., Vannozzi I., Viacava P., Poli A. Correlation of vascular endothelial growth factor expression to overall survival in feline invasive mammary carcinomas. Veterinary Pathology 2002, 39:690-696.
30. Misdorp W., Else W., Hellmen E., Lipscomb T.P. Histological classification of the mammary tumours of the dog and the cat. World Health Organization International Histological Classification of Tumours of the Domestic Animals 1999, vol. 7:11-56. Armed Forces Institute of Pathology, Washington, DC, (2nd Series).
31. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacological Reviews 1991, 43:109-142.
32. Pepper M.S., Baetens D., Mandriota S.J., Di Santa C., Oikemus S., Lane T.F., Soriano J.V., Montesano R., Iruela-Arispe M.L. Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution. Developmental Dynamics 2000, 218:507-524.
33. Restucci B., Papparella S., Maiolino P., De Vico G. Expression of vascular endothelial growth factor in canine mammary tumours. Veterinary Pathology 2002, 39:488-493.
34. Reveneau S., Arnould L., Jolimoy G., Hilpert S., Lejeune P., Saint-Giorgio V., Belichard C., Jeannin J.F. Nitric oxide synthase in human breast cancer is associated with tumour grade, proliferation rate, and expression of progesterone receptors. Laboratory Investigation 1999, 79:1215-1225.
35. Seixas F., Palmeira C., Pires M.A., Bento M.J., Lopes C. Grade is an independent prognostic factor for feline mammary carcinomas: A clinicopathological and survival analysis. The Veterinary Journal 2011, 187:65-71.
36. Shweiki D., Itin A., Soffer D., Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992, 359:843-845.
37. Song Z.J., Gong P., Wu Y.E. Relationship between the expression of iNOS, VEGF, tumour angiogenesis and gastric cancer. World Journal of Gastroenterology 2002, 8:591-595.
38. Sugimoto H., Mundel T.M., Kieran M.W., Kalluri R. Identification of fibroblast heterogeneity in the tumour microenvironment. Cancer Biology & Therapy 2006, 5:1640-1646.
39. Thomsen L.L., Miles D.W., Happerfield L., Bobrow L.G., Knowles R.G., Moncada S. Nitric oxide synthase activity in human breast cancer. British Journal of Cancer 1995, 72:41-44.
40. Tschugguel W., Knogler W., Czerwenka K., Mildner M., Weninger W., Zeillinger R., Huber J.C. Presence of endothelial calcium-dependent nitric oxide synthase in breast apocrine metaplasia. British Journal of Cancer 1996, 74:1423-1426.
41. Tschugguel W., Schneeberger C., Unfried G., Czerwenka K., Weninger W., Mildner M., Gruber D.M., Sator M.O., Waldhör T., Huber J.C. Expression of inducible nitric oxide synthase in human breast cancer depends on tumour grade. Breast Cancer Research and Treatment 1999, 56:145-151.
42. Vakkala M., Kahlos K., Lakari E., Pääkkö P., Kinnula V., Soini Y. Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast cancer. Clinical Cancer Research 2000, 6:2408-2416.
43. Vakkala M., Pääkkö P., Soini Y. eNOS expression is associated with the estrogen and progesterone receptor status in invasive breast carcinoma. International Journal of Oncology 2000, 17:667-671.
44. Van Buren G., Camp E.R., Yang A.D., Gray M.J., Fan F., Somcio R., Ellis L.M. The role of nitric oxide in mediating tumour blood flow. Expert Opinion on Therapeutic Targets 2006, 10:689-701.
45. Xu W., Liu L.Z., Loizidou M., Ahmed M., Charles I.G. The role of nitric oxide in cancer. Cell Research 2002, 123:311-320.
46. Yamashita M., Ogawa T., Zhang X., Hanamura N., Kashikura Y., Takamura M., Yoneda M., Shiraishi T. Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome. Breast Cancer 2010, (Epub ahead of print). 10.1007/s12282-010-0234-5.
47. Yazhou C., Wenlv S., Weidong Z., Licun W. Clinicopathological significance of stromal myofibroblasts in invasive ductal carcinoma of the breast. Tumour Biology 2004, 25:290-295.
48. Ziche M., Morbidelli L., Choudhuri R., Zhang H.T., Donnini S., Granger H.J. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. Journal of Clinical Investigation 1997, 99:2625-2634.