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Volumn 89, Issue SUPPL.1, 2009, Pages

Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses

Author keywords

Cytokine; ESAT 6; Human; Transcription factor; Tuberculosis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; BACTERIAL PROTEIN; CULTURE FILTRATE PROTEIN 10; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; MESSENGER RNA; PROTEIN C JUN; PROTEIN ESX 1; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 72049083462     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-9792(09)70017-4     Document Type: Article
Times cited : (43)

References (18)
  • 1
    • 0028904655 scopus 로고
    • Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice
    • Andersen P., Andersen A.B., Sorensen A.L., and Nagai S. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J Immunol 154 (1995) 3359-3372
    • (1995) J Immunol , vol.154 , pp. 3359-3372
    • Andersen, P.1    Andersen, A.B.2    Sorensen, A.L.3    Nagai, S.4
  • 2
    • 0028966384 scopus 로고
    • Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis
    • Sorensen A.L., Nagai S., Houen G., Andersen P., and Andersen A.B. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 63 (1995) 1710-1717
    • (1995) Infect Immun , vol.63 , pp. 1710-1717
    • Sorensen, A.L.1    Nagai, S.2    Houen, G.3    Andersen, P.4    Andersen, A.B.5
  • 3
    • 0030025636 scopus 로고    scopus 로고
    • Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG
    • Harboe M., Oettinger T., Wiker H.G., Rosenkrands I., and Andersen P. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infect Immun 64 (1996) 16-22
    • (1996) Infect Immun , vol.64 , pp. 16-22
    • Harboe, M.1    Oettinger, T.2    Wiker, H.G.3    Rosenkrands, I.4    Andersen, P.5
  • 4
    • 0031767535 scopus 로고    scopus 로고
    • A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)
    • Berthet F.X., Rasmussen P.B., Rosenkrands I., Andersen P., and Gicquel B. A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10). Microbiology (Reading) 144 Pt 11 (1998) 3195-3203
    • (1998) Microbiology (Reading) , vol.144 , Issue.PART 11 , pp. 3195-3203
    • Berthet, F.X.1    Rasmussen, P.B.2    Rosenkrands, I.3    Andersen, P.4    Gicquel, B.5
  • 6
    • 48749127991 scopus 로고    scopus 로고
    • Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update
    • Pai M., Zwerling A., and Menzies D. Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Ann Intern Med 149 (2008) 177-184
    • (2008) Ann Intern Med , vol.149 , pp. 177-184
    • Pai, M.1    Zwerling, A.2    Menzies, D.3
  • 7
    • 0029920827 scopus 로고    scopus 로고
    • Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis
    • Mahairas G.G., Sabo P.J., Hickey M.J., Singh D.C., and Stover C.K. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J Bacteriol 178 (1996) 1274-1282
    • (1996) J Bacteriol , vol.178 , pp. 1274-1282
    • Mahairas, G.G.1    Sabo, P.J.2    Hickey, M.J.3    Singh, D.C.4    Stover, C.K.5
  • 8
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393 (1998) 537-544
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3    Garnier, T.4    Churcher, C.5    Harris, D.6
  • 9
    • 0037077299 scopus 로고    scopus 로고
    • Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence
    • Renshaw P.S., Panagiotidou P., Whelan A., Gordon S.V., Hewinson R.G., Williamson R.A., et al. Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence. J Biol Chem 277 (2002) 21598-21603
    • (2002) J Biol Chem , vol.277 , pp. 21598-21603
    • Renshaw, P.S.1    Panagiotidou, P.2    Whelan, A.3    Gordon, S.V.4    Hewinson, R.G.5    Williamson, R.A.6
  • 10
    • 0942290453 scopus 로고    scopus 로고
    • Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis
    • Guinn K.M., Hickey M.J., Mathur S.K., Zakel K.L., Grotzke J.E., Lewinsohn D.M., et al. Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis. Mol Microbiol 51 (2004) 359-370
    • (2004) Mol Microbiol , vol.51 , pp. 359-370
    • Guinn, K.M.1    Hickey, M.J.2    Mathur, S.K.3    Zakel, K.L.4    Grotzke, J.E.5    Lewinsohn, D.M.6
  • 11
    • 0142059794 scopus 로고    scopus 로고
    • The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue
    • Hsu T., Hingley-Wilson S.M., Chen B., Chen M., Dai A.Z., Morin P.M., et al. The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proc Natl Acad Sci USA 100 (2003) 12420-12425
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12420-12425
    • Hsu, T.1    Hingley-Wilson, S.M.2    Chen, B.3    Chen, M.4    Dai, A.Z.5    Morin, P.M.6
  • 12
    • 0242268398 scopus 로고    scopus 로고
    • Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
    • Stanley S.A., Raghavan S., Hwang W.W., and Cox J.S. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc Natl Acad Sci USA 100 (2003) 13001-13006
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13001-13006
    • Stanley, S.A.1    Raghavan, S.2    Hwang, W.W.3    Cox, J.S.4
  • 13
    • 33847359299 scopus 로고    scopus 로고
    • The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
    • Stanley S.A., Johndrow J.E., Manzanillo P., and Cox J.S. The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J Immunol 178 (2007) 3143-3152
    • (2007) J Immunol , vol.178 , pp. 3143-3152
    • Stanley, S.A.1    Johndrow, J.E.2    Manzanillo, P.3    Cox, J.S.4
  • 14
    • 34249012130 scopus 로고    scopus 로고
    • Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
    • Pathak S.K., Basu S., Basu K.K., Banerjee A., Pathak S., Bhattacharyya A., et al. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nat Immunol 8 (2007) 610-618
    • (2007) Nat Immunol , vol.8 , pp. 610-618
    • Pathak, S.K.1    Basu, S.2    Basu, K.K.3    Banerjee, A.4    Pathak, S.5    Bhattacharyya, A.6
  • 15
    • 65449188659 scopus 로고    scopus 로고
    • ESAT-6 inhibits production of IFN-g by Mycobacterium tuberculosis-responsive human T cells
    • Wang X., Barnes P.F., Dobos-Elder K.M., Townsend J.C., Chung Y.-T., Shams H., et al. ESAT-6 inhibits production of IFN-g by Mycobacterium tuberculosis-responsive human T cells. J Immunol 182 (2009) 3668-3677
    • (2009) J Immunol , vol.182 , pp. 3668-3677
    • Wang, X.1    Barnes, P.F.2    Dobos-Elder, K.M.3    Townsend, J.C.4    Chung, Y.-T.5    Shams, H.6
  • 16
    • 18644370311 scopus 로고    scopus 로고
    • Cyclic AMP response element-binding protein positively regulates production of IFN-gamma by T cells in response to a microbial pathogen
    • Samten B., Howard S.T., Weis S.E., Wu S., Shams H., Townsend J.C., et al. Cyclic AMP response element-binding protein positively regulates production of IFN-gamma by T cells in response to a microbial pathogen. J Immunol 174 (2005) 6357-6363
    • (2005) J Immunol , vol.174 , pp. 6357-6363
    • Samten, B.1    Howard, S.T.2    Weis, S.E.3    Wu, S.4    Shams, H.5    Townsend, J.C.6
  • 17
    • 49649120693 scopus 로고    scopus 로고
    • CREB, ATF, and AP-1 transcription factors regulate IFN-gamma secretion by human T cells in response to mycobacterial antigen
    • Samten B., Townsend J.C., Weis S.E., Bhoumik A., Klucar P., Shams H., et al. CREB, ATF, and AP-1 transcription factors regulate IFN-gamma secretion by human T cells in response to mycobacterial antigen. J Immunol 181 (2008) 2056-2064
    • (2008) J Immunol , vol.181 , pp. 2056-2064
    • Samten, B.1    Townsend, J.C.2    Weis, S.E.3    Bhoumik, A.4    Klucar, P.5    Shams, H.6
  • 18
    • 0030250114 scopus 로고    scopus 로고
    • Complex complexes: signaling at the TCR
    • Wange R.L., and Samelson L.E. Complex complexes: signaling at the TCR. Immunity 5 (1996) 197-205
    • (1996) Immunity , vol.5 , pp. 197-205
    • Wange, R.L.1    Samelson, L.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.