A trimer of dimers is the basic building block for human immunodeficiency virus-1 capsid assembly

Biochemistry

Volumn 51, Issue 22, 2012, Pages 4416-4428

  Tsiang, Manuel ^a   Niedziela Majka, Anita ^a   Hung, Magdeleine ^a   Jin, Debi ^a   Hu, Eric ^a   Yant, Stephen ^a   Samuel, Dharmaraj ^a   Liu, Xiaohong ^a   Sakowicz, Roman ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-VIRAL DRUGS; BASIC BUILDING BLOCK; BINDING AGENT; BIOPHYSICAL PARAMETERS; BUILDING BLOCKES; CAPSID ASSEMBLIES; CAPSID PROTEINS; COMPARATIVE ANALYSIS; DISSOCIATION CONSTANT; DRUG DISCOVERY; EQUILIBRIUM MODELS; HEXAMERS; HUMAN IMMUNODEFICIENCY VIRUS-1; IN-VITRO; KINETIC ANALYSIS; MATHEMATICAL MODELING; NEW MATHEMATICAL MODEL; POLYMER GROWTH; POLYMER TUBES; POLYMERIZATION PROCESS; SMALL MOLECULES; TRIANGULAR GEOMETRY; TRIMERIZATION; WILD TYPES;

CROSSLINKING; DISSOCIATION; MOLECULES; POLYMERIZATION; POLYMERS; PROTEINS; TUBES (COMPONENTS);

DIMERS;

CAPSID PROTEIN; DIMER; POLYMER; TRIMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOPHYSICS; CROSS LINKING; GEOMETRY; HUMAN IMMUNODEFICIENCY VIRUS 1; KINETICS; LIFE CYCLE; MATHEMATICAL MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN POLYMERIZATION; VIRUS CAPSID; WILD TYPE;

CAPSID; CAPSID PROTEINS; COMPUTER SIMULATION; HIV INFECTIONS; HIV-1; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; POLYMERIZATION; PROTEIN MULTIMERIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE;

EID: 84861853801     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300052h     Document Type: Article

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