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Volumn 51, Issue 7, 2012, Pages 576-585

2-Methoxyestradiol induced bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation

Author keywords

2 methoxyestradiol; Apoptosis; P38 MAPK; Phospho Bax; Retinoblastoma

Indexed keywords

2 METHOXYESTRADIOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; THREONINE;

EID: 84861839598     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20825     Document Type: Article
Times cited : (19)

References (38)
  • 2
    • 0020263982 scopus 로고
    • Retinoblastoma: Diagnosis and management
    • Abramson DH. Retinoblastoma: Diagnosis and management. CA Cancer J Clin 1982; 32: 130-140.
    • (1982) CA Cancer J Clin , vol.32 , pp. 130-140
    • Abramson, D.H.1
  • 3
    • 0033754920 scopus 로고    scopus 로고
    • Presence of human papilloma virus in tumor tissue from children with retinoblastoma: An alternative mechanism for tumor development
    • Orjuela M, Castaneda VP, Ridaura C, et al. Presence of human papilloma virus in tumor tissue from children with retinoblastoma: An alternative mechanism for tumor development. Clin Cancer Res 2000; 6: 4010-4016.
    • (2000) Clin Cancer Res , vol.6 , pp. 4010-4016
    • Orjuela, M.1    Castaneda, V.P.2    Ridaura, C.3
  • 4
    • 0037032474 scopus 로고    scopus 로고
    • Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells
    • Bu S, Blaukat A, Fu X, Heldin NE, Landström M. Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells. FEBS Lett 2002; 531: 141-151.
    • (2002) FEBS Lett , vol.531 , pp. 141-151
    • Bu, S.1    Blaukat, A.2    Fu, X.3    Heldin, N.E.4    Landström, M.5
  • 6
    • 0037439693 scopus 로고    scopus 로고
    • 2-Methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway
    • LaVallee TM, Zhan XH, Johnson MS, et al. 2-Methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway. Cancer Res 2003; 63: 468-475.
    • (2003) Cancer Res , vol.63 , pp. 468-475
    • LaVallee, T.M.1    Zhan, X.H.2    Johnson, M.S.3
  • 7
    • 14944384245 scopus 로고    scopus 로고
    • Apoptosis signaling in tumor therapy
    • Fulda S, Debatin KM. Apoptosis signaling in tumor therapy. Ann NY Acad Sci 2004; 1028: 150-156.
    • (2004) Ann NY Acad Sci , vol.1028 , pp. 150-156
    • Fulda, S.1    Debatin, K.M.2
  • 8
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
    • Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human. Physiol Rev 1999; 79: 143-180.
    • (1999) Physiol Rev , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 10
    • 0038011249 scopus 로고    scopus 로고
    • Roles of p38- and c-Jun NH2-terminal kinase-mediated pathways in 2-Methoxyestradiol-induced p53 induction and apoptosis
    • Shimada K, Nakamura M, Ishida E, Kishi M, Konishi N. Roles of p38- and c-Jun NH2-terminal kinase-mediated pathways in 2-Methoxyestradiol-induced p53 induction and apoptosis. Carcinogenesis 2003; 24: 1067-1075.
    • (2003) Carcinogenesis , vol.24 , pp. 1067-1075
    • Shimada, K.1    Nakamura, M.2    Ishida, E.3    Kishi, M.4    Konishi, N.5
  • 11
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • Oltval Z, Milliman C, Korsmeyer S. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 1993; 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltval, Z.1    Milliman, C.2    Korsmeyer, S.3
  • 12
    • 0031784625 scopus 로고    scopus 로고
    • Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype
    • De Angelis PM, Stokke T, Thorstensen L, Lothe RA, Clausen OP. Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype. Mol Pathol 1998; 51: 254-261.
    • (1998) Mol Pathol , vol.51 , pp. 254-261
    • De Angelis, P.M.1    Stokke, T.2    Thorstensen, L.3    Lothe, R.A.4    Clausen, O.P.5
  • 13
    • 33746379603 scopus 로고    scopus 로고
    • JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
    • Kim BJ, Ryu SW, Song BJ. JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J Biol Chem 2006; 281: 21256-21265.
    • (2006) J Biol Chem , vol.281 , pp. 21256-21265
    • Kim, B.J.1    Ryu, S.W.2    Song, B.J.3
  • 14
    • 0033593230 scopus 로고    scopus 로고
    • Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
    • Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG, Green DR. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 1999; 274: 2225-2233.
    • (1999) J Biol Chem , vol.274 , pp. 2225-2233
    • Finucane, D.M.1    Bossy-Wetzel, E.2    Waterhouse, N.J.3    Cotter, T.G.4    Green, D.R.5
  • 16
    • 2442681877 scopus 로고    scopus 로고
    • Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils
    • Gardai SJ, Hildeman DA, Frankel SK, et al. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J Biol Chem 2004; 279: 21085-21095.
    • (2004) J Biol Chem , vol.279 , pp. 21085-21095
    • Gardai, S.J.1    Hildeman, D.A.2    Frankel, S.K.3
  • 17
    • 7744227096 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis
    • Linseman DA, Butts BD, Precht TA, et al. Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis. J Neurosci 2004; 24: 9993-10002.
    • (2004) J Neurosci , vol.24 , pp. 9993-10002
    • Linseman, D.A.1    Butts, B.D.2    Precht, T.A.3
  • 18
    • 0025200520 scopus 로고
    • DNA florometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distill water
    • Rago R, Mitchen J, Wilding G. DNA florometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distill water. Anal Biochem 1990; 191: 31-34.
    • (1990) Anal Biochem , vol.191 , pp. 31-34
    • Rago, R.1    Mitchen, J.2    Wilding, G.3
  • 19
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelöv LL, Christensen IJ, Nissen NI. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 1983; 3: 323-327.
    • (1983) Cytometry , vol.3 , pp. 323-327
    • Vindelöv, L.L.1    Christensen, I.J.2    Nissen, N.I.3
  • 20
    • 33646390930 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2
    • Bu SZ, Huang Q, Jiang Y, et al. p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2. Apoptosis 2006; 11: 413-425.
    • (2006) Apoptosis , vol.11 , pp. 413-425
    • Bu, S.Z.1    Huang, Q.2    Jiang, Y.3
  • 21
    • 1842633297 scopus 로고    scopus 로고
    • Systemic chemotherapy as a new conservative treatment for intraocular retinoblastoma
    • Yanagisawa T. Systemic chemotherapy as a new conservative treatment for intraocular retinoblastoma. Int J Clin Oncol 2004; 9: 13-24.
    • (2004) Int J Clin Oncol , vol.9 , pp. 13-24
    • Yanagisawa, T.1
  • 22
    • 1842734108 scopus 로고    scopus 로고
    • Management of intraocular retinoblastoma and ocular prognosis
    • Suzuki S, Kaneko A. Management of intraocular retinoblastoma and ocular prognosis. Int J Clin Oncol 2004; 9: 1-6.
    • (2004) Int J Clin Oncol , vol.9 , pp. 1-6
    • Suzuki, S.1    Kaneko, A.2
  • 24
    • 58849135484 scopus 로고    scopus 로고
    • Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells
    • Fukui M, Zhu BT. Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells. Mol Carcinog 2009; 48: 66-78.
    • (2009) Mol Carcinog , vol.48 , pp. 66-78
    • Fukui, M.1    Zhu, B.T.2
  • 25
    • 14544273363 scopus 로고    scopus 로고
    • Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells
    • Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T. Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. J Mol Endocrinol 2005; 34: 91-105.
    • (2005) J Mol Endocrinol , vol.34 , pp. 91-105
    • Lewis, J.S.1    Thomas, T.J.2    Pestell, R.G.3    Albanese, C.4    Gallo, M.A.5    Thomas, T.6
  • 26
    • 78650246609 scopus 로고    scopus 로고
    • Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells
    • Fotopoulou C, Baumunk D, Schmidt S, Schumacher G. Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells. Anticancer Res 2010; 30: 4619-4624.
    • (2010) Anticancer Res , vol.30 , pp. 4619-4624
    • Fotopoulou, C.1    Baumunk, D.2    Schmidt, S.3    Schumacher, G.4
  • 27
    • 63149115931 scopus 로고    scopus 로고
    • Phase I trial of 2-methoxyestradiol NanoCrystal dispersion in advanced solid malignancies
    • Tevaarwerk AJ, Holen KD, Alberti DB, et al. Phase I trial of 2-methoxyestradiol NanoCrystal dispersion in advanced solid malignancies. Clin Cancer Res 2009; 15: 1460-1465.
    • (2009) Clin Cancer Res , vol.15 , pp. 1460-1465
    • Tevaarwerk, A.J.1    Holen, K.D.2    Alberti, D.B.3
  • 28
    • 32544433479 scopus 로고    scopus 로고
    • Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors
    • Dahut WL, Lakhani NJ, Gulley JL, et al. Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 2006; 5: 22-27.
    • (2006) Cancer Biol Ther , vol.5 , pp. 22-27
    • Dahut, W.L.1    Lakhani, N.J.2    Gulley, J.L.3
  • 29
    • 70449107007 scopus 로고    scopus 로고
    • Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis
    • Autret A, Martin SJ. Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis. Mol Cell 2009; 36: 355-363.
    • (2009) Mol Cell , vol.36 , pp. 355-363
    • Autret, A.1    Martin, S.J.2
  • 31
    • 42049103183 scopus 로고    scopus 로고
    • Regulation of Bcl-2 family proteins by posttranslational modifications
    • Kutuk O, Letai A. Regulation of Bcl-2 family proteins by posttranslational modifications. Curr Mol Med 2008; 8: 102-118.
    • (2008) Curr Mol Med , vol.8 , pp. 102-118
    • Kutuk, O.1    Letai, A.2
  • 32
    • 0037159575 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells
    • Kuo PL, Chiang LC, Lin CC. Resveratrol-induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells. Life Sci 2002; 72: 23-34.
    • (2002) Life Sci , vol.72 , pp. 23-34
    • Kuo, P.L.1    Chiang, L.C.2    Lin, C.C.3
  • 33
    • 78751578983 scopus 로고    scopus 로고
    • The role of peripheral gonadotropin-releasing hormone receptors in female reproduction
    • Yu B, Ruman J, Christman G. The role of peripheral gonadotropin-releasing hormone receptors in female reproduction. Fertil Steril 2011; 95: 465-473.
    • (2011) Fertil Steril , vol.95 , pp. 465-473
    • Yu, B.1    Ruman, J.2    Christman, G.3
  • 34
    • 77955617901 scopus 로고    scopus 로고
    • Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components
    • Sun S, Li XL, Wang CZ, Williams S, Yuan CS. Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components. Phytother Res 2010; 24: 1166-1174.
    • (2010) Phytother Res , vol.24 , pp. 1166-1174
    • Sun, S.1    Li, X.L.2    Wang, C.Z.3    Williams, S.4    Yuan, C.S.5
  • 35
    • 0032103027 scopus 로고    scopus 로고
    • The Fas counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma
    • Bennett MW, O'Connell J, O'Sullivan GC, et al. The Fas counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J Immunol 1998; 160: 5669-5675.
    • (1998) J Immunol , vol.160 , pp. 5669-5675
    • Bennett, M.W.1    O'Connell, J.2    O'Sullivan, G.C.3
  • 36
    • 0029103598 scopus 로고
    • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod KF, Sherry N, Hannon G, et al. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 1995; 9: 935-944.
    • (1995) Genes Dev , vol.9 , pp. 935-944
    • Macleod, K.F.1    Sherry, N.2    Hannon, G.3
  • 37
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr CJ. G1 phase progression: Cycling on cue. Cell 1994; 79: 551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 38
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev 1999; 13: 1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.