Systematic comparison of fractionation methods for in-depth analysis of plasma proteomes

Journal of Proteome Research

Volumn 11, Issue 6, 2012, Pages 3090-3100

  Cao, Zhijun ^a   Tang, Hsin Yao ^a   Wang, Huan ^a   Liu, Qin ^a   Speicher, David W ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

biomarker discovery; biomarker validation; biomarkers; human plasma; Plasma proteome; protein profiling; proteome fractionation

Indexed keywords

PLASMA PROTEIN; PROTEOME; BIOLOGICAL MARKER; PEPTIDE FRAGMENT;

ARTICLE; CONCENTRATION (PARAMETERS); HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; ISOELECTRIC FOCUSING; ISOTOPE DILUTION ASSAY; PH; PLASMA; PLASMA VOLUME; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; SERUM; SIGNAL TRANSDUCTION; VALIDATION STUDY; BLOOD; BLOOD ANALYSIS; COMPARATIVE STUDY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOPRECIPITATION; ISOLATION AND PURIFICATION; METABOLISM; TANDEM MASS SPECTROMETRY;

BIOLOGICAL MARKERS; BLOOD CHEMICAL ANALYSIS; BLOOD PROTEINS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOPRECIPITATION; ISOELECTRIC FOCUSING; PEPTIDE FRAGMENTS; PROTEOME; TANDEM MASS SPECTROMETRY;

EID: 84861838336     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr201068b     Document Type: Article

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