Commentary: Does needle injection cause disc degeneration? News in the continuing debate regarding pathophysiology associated with intradiscal injections

Spine Journal

Volumn 12, Issue 4, 2012, Pages 336-338

  Iatridis, James C ^a   Hecht, Andrew C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; BUPIVACAINE; CONTRAST MEDIUM; LIDOCAINE;

APOPTOSIS; CARTILAGE CELL; CELL CULTURE; CELL DEATH; CELL DENSITY; CELL PROLIFERATION; CELL VIABILITY; CYTOTOXICITY; DISKOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INJECTION; INTERVERTEBRAL DISK DEGENERATION; INTERVERTEBRAL DISK HERNIA; LOW BACK PAIN; NEEDLE; NOCICEPTION; NONHUMAN; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIOGRAPHY;

APOPTOSIS; ARTHROGRAPHY; CONTRAST MEDIA; FEMALE; HUMANS; INTERVERTEBRAL DISC; IOPAMIDOL; MALE;

EID: 84861798026     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2012.03.006     Document Type: Note

References (23)

1. H.E. Gruber, A.L. Rhyne, and K.J. Hansen Deleterious effects of discography radiocontrast solution on human annulus cell in vitro: changes in cell viability, proliferation, and apoptosis in exposed cells Spine J 12 2012 329 335
2. J.D. Kang Does a needle puncture into the annulus fibrosus cause disc degeneration? Spine J 10 2010 1106 1107
3. E.J. Carragee, T. Lincoln, V.S. Parmar, and T. Alamin A gold standard evaluation of the "discogenic pain" diagnosis as determined by provocative discography Spine 31 2006 2115 2123
4. E.J. Carragee, A.S. Don, and E.L. Hurwitz 2009 ISSLS Prize Winner: does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study Spine 34 2009 2338 2345
5. K. Masuda, Y. Aota, and C. Muehleman A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration Spine 30 2005 5 14
6. S. Sobajima, J.F. Kompel, and J.S. Kim A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology Spine 30 2005 15 24
7. C.L. Korecki, J.J. Costi, and J.C. Iatridis Needle puncture injury affects intervertebral disc mechanics and biology in an organ culture model Spine 33 2008 235 241
8. A.J. Michalek, M.R. Buckley, and L.J. Bonassar The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus Spine J 10 2010 1098 1105
9. D.M. Elliott, C.S. Yerramalli, and J.C. Beckstein The effect of relative needle diameter in puncture and sham injection animal models of degeneration Spine 33 2008 588 596
10. Iatridis JC, Nicoll SB, Michalek AJ, et al. Role of biomechanics on intervertebral disc degeneration and regenerative therapies: what needs repairing in the IVD and what are promising biomaterials for its repair? Spine J. In press.
11. V.M. Haughton, B. Rogers, M.E. Meyerand, and D.K. Resnick Measuring the axial rotation of lumbar vertebrae in vivo with MR imaging AJNR Am J Neuroradiol 23 2002 1110 1116
12. N.L. Fazzalari, J.J. Costi, and T.C. Hearn Mechanical and pathologic consequences of induced concentric anular tears in an ovine model Spine 26 2001 2575 2581
13. J.C. Iatridis, and I. ap Gwynn Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus J Biomech 37 2004 1165 1175
14. M. Alini, S.M. Eisenstein, and K. Ito Are animal models useful for studying human disc disorders/degeneration? Eur Spine J 17 2008 2 19
15. An HS, Ren J, Zhang Y, Chee A. Effects of local anesthetic and nonionic contrast agents on bovine intervertebral disc cells cultured in alginate. Proceedings of the Cervical Spine Research Society; 2010; 103-4.
16. L. Quero, M. Klawitter, and A.G. Nerlich Bupivacaine-the deadly friend of intervertebral disc cells? Spine J 11 2011 46 53
17. D. Wang, N.V. Vo, and G.A. Sowa Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system Spine J 11 2011 139 146
18. J.C. Karpie, and C.R. Chu Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro Am J Sports Med 35 2007 1621 1627
19. C.R. Chu, N.J. Izzo, N.E. Papas, and F.H. Fu In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes Arthroscopy 22 2006 693 699
20. C.R. Chu, C.H. Coyle, and C.T. Chu In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage J Bone Joint Surg Am 92 2010 599 608
21. H.E. Gruber, and E.N. Hanley Jr. Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation BMC Musculoskelet Disord 1 2000 1
22. L. Cao, F. Guilak, and L.A. Setton Pericellular matrix mechanics in the anulus fibrosus predicted by a three-dimensional finite element model and in situ morphology Cell Mol Bioeng 2 2009 306 319
23. R. Gawri, F. Mwale, and J. Ouellet Development of an organ culture system for long term survival of the intact human intervertebral disc Spine 36 2011 1835 1842