PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI

Blood

Volumn 119, Issue 22, 2012, Pages 5285-5293

  Kasthuri, Raj S ^a   Glover, Sam L ^a   Jonas, William ^a   McEachron, Troy ^a   Pawlinski, Rafal ^a   Arepally, Gowthami M ^b   Key, Nigel S ^a   Mackman, Nigel ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; FC GAMMA RECEPTOR 1; HEPARIN; IMMUNOGLOBULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MONOCLONAL ANTIBODY; THROMBOCYTE FACTOR 4; THROMBOPLASTIN; UNCLASSIFIED DRUG;

ARTICLE; EX VIVO STUDY; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; HUMAN CELL; HUMAN TISSUE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA; PLATELET MICROPARTICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THROMBOCYTE COUNT; THROMBOSIS;

EID: 84861793285     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-06-359430     Document Type: Article

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