-
2
-
-
84861762818
-
The emperor of all maladies
-
book review
-
Marks, P. A. (2011) The emperor of all maladies (book review). FASEB J. 25, 1786-1787
-
(2011)
FASEB J.
, vol.25
, pp. 1786-1787
-
-
Marks, P.A.1
-
3
-
-
84861761414
-
On cancer and people
-
book review
-
Pederson, T. (2011) On cancer and people (book review). Science 332, 423
-
(2011)
Science
, vol.332
, pp. 423
-
-
Pederson, T.1
-
4
-
-
84914454996
-
Inhibition of dihydrofolic reductase by aminopterin and amethopterin
-
Osborn, M. J., Freeman, M., and Huennekens, F. M. (1958) Inhibition of dihydrofolic reductase by aminopterin and amethopterin. Proc. Soc. Exp. Biol. Med. 97, 429-431
-
(1958)
Proc. Soc. Exp. Biol. Med.
, vol.97
, pp. 429-431
-
-
Osborn, M.J.1
Freeman, M.2
Huennekens, F.M.3
-
5
-
-
0001037342
-
The mode of action of 5-fluorouracil and its derivatives
-
Cohen, S. S., Flaks, J. G., Barner, H. D., Loeb, M. R., and Lichtenstein, J. (1958) The mode of action of 5-fluorouracil and its derivatives. Proc. Natl. Acad. Sci. USA 44, 1004-1012
-
(1958)
Proc. Natl. Acad. Sci. USA
, vol.44
, pp. 1004-1012
-
-
Cohen, S.S.1
Flaks, J.G.2
Barner, H.D.3
Loeb, M.R.4
Lichtenstein, J.5
-
6
-
-
84861762499
-
-
(L. L. Brunton, B. A. Chabner, and B. C. Knollmann, eds.), 12th Ed., McGraw-Hill, New York
-
Chabner, B. A., Bertino, J., Cleary, J., Ortiz, T., Lane, A., Supko, J. G., and Ryan, D. (2011) In Goodman & Gilman's Pharmacological Basis of Therapeutics (L. L. Brunton, B. A. Chabner, and B. C. Knollmann, eds.), 12th Ed., McGraw-Hill, New York, 1667-1730
-
(2011)
Goodman & Gilman's Pharmacological Basis of Therapeutics
, pp. 1667-1730
-
-
Chabner, B.A.1
Bertino, J.2
Cleary, J.3
Ortiz, T.4
Lane, A.5
Supko, J.G.6
Ryan, D.7
-
7
-
-
0001051251
-
Specific binding of 4-amino folic acid analogs by folic acid reductase
-
Werkheiser, W. C. (1961) Specific binding of 4-amino folic acid analogs by folic acid reductase. J. Biol. Chem. 236, 888-893
-
(1961)
J. Biol. Chem.
, vol.236
, pp. 888-893
-
-
Werkheiser, W.C.1
-
8
-
-
0001628618
-
Further studies on dihydrofolic reductase
-
Mathews, C. K., and Huennekens, F. M. (1963) Further studies on dihydrofolic reductase. J. Biol. Chem. 238, 3436-3442
-
(1963)
J. Biol. Chem.
, vol.238
, pp. 3436-3442
-
-
Mathews, C.K.1
Huennekens, F.M.2
-
9
-
-
0015523736
-
Spectral changes associated with binding of folate compounds to bacteriophage T4 dihydrofolate reductase
-
Erickson, J. S., and Mathews, C. K. (1972) Spectral changes associated with binding of folate compounds to bacteriophage T4 dihydrofolate reductase. J. Biol. Chem. 247, 5661-5667
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 5661-5667
-
-
Erickson, J.S.1
Mathews, C.K.2
-
10
-
-
0020441466
-
Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution. I. General features and binding of methotrexate
-
Bolin, J. T., Filman, D. J., Matthews, D. A., Hamlin, R. C., and Kraut, J. (1982) Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution. J. Biol. Chem. 257, 13650-13662 (Pubitemid 13187127)
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.22
, pp. 13650-13662
-
-
Bolin, J.T.1
Filman, D.J.2
Matthews, D.A.3
-
11
-
-
0000875305
-
Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase
-
Hartmann, K-U., and Heidelberger, C. (1961) Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase. J. Biol. Chem. 236, 3006-3013
-
(1961)
J. Biol. Chem.
, vol.236
, pp. 3006-3013
-
-
Hartmann, K.-U.1
Heidelberger, C.2
-
12
-
-
84861777896
-
Inhibition of phage-induced thymidylate synthetase by 5-fluorodeoxyuridylate
-
Mathews, C. K., and Cohen, S. S. (1963) Inhibition of phage-induced thymidylate synthetase by 5-fluorodeoxyuridylate. J. Biol. Chem. 238, 367-370
-
(1963)
J. Biol. Chem.
, vol.238
, pp. 367-370
-
-
Mathews, C.K.1
Cohen, S.S.2
-
13
-
-
0000299873
-
Folates in pyrimidine nucleotide biosynthesis
-
(R. L. Blakley and S. J. Benkovic, eds.), John Wiley & Sons, New York
-
Santi, D. V., and Danenberg, P. V. (1984) Folates in pyrimidine nucleotide biosynthesis. In Folates and Pterins, (R. L. Blakley and S. J. Benkovic, eds.), John Wiley & Sons, New York, 345-398
-
(1984)
Folates and Pterins
, pp. 345-398
-
-
Santi, D.V.1
Danenberg, P.V.2
-
14
-
-
0002242695
-
Direct spectrophotometric evidence for the oxidation of tetrahydrofolate during the enzymatic synthesis of thymidylate
-
Wahba, A. J., and Friedkin, M. (1961) Direct spectrophotometric evidence for the oxidation of tetrahydrofolate during the enzymatic synthesis of thymidylate. J. Biol. Chem. 236, PC11-PC12
-
(1961)
J. Biol. Chem.
, vol.236
-
-
Wahba, A.J.1
Friedkin, M.2
-
15
-
-
0022642429
-
Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells
-
Matherly, L. H., Barlowe, C. K., and Goldman, I. D. (1986) Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells. Cancer Res. 46, 588-593 (Pubitemid 16145406)
-
(1986)
Cancer Research
, vol.46
, Issue.2
, pp. 588-593
-
-
Matherly, L.H.1
Barlowe, C.K.2
Goldman, I.D.3
-
16
-
-
0021735425
-
Gene amplification in cultured animal cells
-
Schimke, R. T. (1984) Gene amplification in cultured animal cells. Cell 37, 705-713
-
(1984)
Cell
, vol.37
, pp. 705-713
-
-
Schimke, R.T.1
-
17
-
-
0014800626
-
Chemical carcinogenesis, chemotherapy: Cancer's continuing core challenges - G. H. A. Clowes Memorial Lecture
-
Heidelberger, C. (1970) Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges - G. H. A. Clowes Memorial Lecture. Cancer Res. 30, 1549-1569
-
(1970)
Cancer Res.
, vol.30
, pp. 1549-1569
-
-
Heidelberger, C.1
-
18
-
-
0030991713
-
Use of strain in a stereospecific catalytic mechanism: Crystal structures of Escherichia coli thymidylate synthase bound to FdUMP and methylenetetrahydrofolate
-
DOI 10.1021/bi962936j
-
Hyatt, D. C., Maley, F., and Montfort, W. R. (1997) Use of strain in a stereospecific catalytic mechanism: crystal structures of Escherichia coli thymidylate synthase bound to FdUMP and methylenetetrahydrofolate. Biochemistry 36, 4585-4594 (Pubitemid 27180307)
-
(1997)
Biochemistry
, vol.36
, Issue.15
, pp. 4585-4594
-
-
Hyatt, D.C.1
Maley, F.2
Montfort, W.R.3
-
19
-
-
79952097177
-
Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA
-
Grogan, B. C., Parker, J. B., Guminski, A. F., and Stivers, J. T. (2011) Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA. Biochemistry 50, 618-627
-
(2011)
Biochemistry
, vol.50
, pp. 618-627
-
-
Grogan, B.C.1
Parker, J.B.2
Guminski, A.F.3
Stivers, J.T.4
-
20
-
-
0014674946
-
Miscoding caused by 5-fluorouracil
-
Rosen, B., Rothman, F., and Weigert, M. G. (1969) Miscoding caused by 5-fluorouracil. J. Mol. Biol. 44, 363-375
-
(1969)
J. Mol. Biol.
, vol.44
, pp. 363-375
-
-
Rosen, B.1
Rothman, F.2
Weigert, M.G.3
-
21
-
-
0037130280
-
Thymidylate synthase as a translational regulator of cellular gene expression
-
DOI 10.1016/S0925-4439(02)00080-7, PII S0925443902000807
-
Liu, J., Schmitz, J. C., Lin, X., Tai, N., Yan, W., Farrell, M., Bailly, M., Chen, T-M., and Chu, E. (2002) Thymidylate synthase as a translational regulator of cellular gene expression. Biochim. Biophys. Acta 1587, 174-182 (Pubitemid 34655786)
-
(2002)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1587
, Issue.2-3
, pp. 174-182
-
-
Liu, J.1
Schmitz, J.C.2
Lin, X.3
Tai, N.4
Yan, W.5
Farrell, M.6
Bailly, M.7
Chen, T.-M.8
Chu, E.9
-
22
-
-
0017028517
-
The lethality of aranucleotides
-
Cohen, S. S. (1976) The lethality of aranucleotides. Med. Biol. 54, 299-326
-
(1976)
Med. Biol.
, vol.54
, pp. 299-326
-
-
Cohen, S.S.1
-
23
-
-
0026468410
-
Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase α
-
Perrino, F. W., and Mekosh, H. L. (1992) Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase α. J. Biol. Chem. 267, 23043-23051
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23043-23051
-
-
Perrino, F.W.1
Mekosh, H.L.2
-
24
-
-
0023677076
-
Functional consequences of the arabinosylcytosine structural lesion in DNA
-
Mikita, T., and Beardsley, G. P. (1988) Functional consequences of the arabinosylcytosine structural lesion in DNA. Biochemistry 27, 4698-4705
-
(1988)
Biochemistry
, vol.27
, pp. 4698-4705
-
-
Mikita, T.1
Beardsley, G.P.2
-
25
-
-
0027955954
-
Effects of arabinosylcytosine-substituted DNA on DNA/RNA hybrid stability and transcription by T7 RNA polymerase
-
Mikita, T., and Beardsley, G. P. (1994) Effects of arabinosylcytosine- substituted DNA on DNA/RNA hybrid stability and transcription by T7 RNA polymerase. Biochemistry 33, 9195-9208 (Pubitemid 24272871)
-
(1994)
Biochemistry
, vol.33
, Issue.31
, pp. 9195-9208
-
-
Mikita, T.1
Beardsley, G.P.2
-
26
-
-
0014596980
-
Chemotherapy and comparative biochemistry: G. H. A. Clowes Memorial Lecture
-
Hitchings, G. H. (1969) Chemotherapy and comparative biochemistry: G. H. A. Clowes Memorial Lecture. Cancer Res. 29, 1895-1903
-
(1969)
Cancer Res.
, vol.29
, pp. 1895-1903
-
-
Hitchings, G.H.1
-
27
-
-
34250801099
-
The mechanism of action of 6-mercaptopurine. I. Biochemical effects
-
Salser, J. S., and Balis, M. E. (1965) The mechanism of action of 6-mercaptopurine. I. Biochemical effects. Cancer Res. 25, 539-543
-
(1965)
Cancer Res.
, vol.25
, pp. 539-543
-
-
Salser, J.S.1
Balis, M.E.2
-
28
-
-
0016053706
-
A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine
-
Todd, D. M., and Paterson, A. R. P. (1974) A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine. Cancer Res. 34, 738-746
-
(1974)
Cancer Res.
, vol.34
, pp. 738-746
-
-
Todd, D.M.1
Paterson, A.R.P.2
-
29
-
-
0034072173
-
Interaction of deoxyguanosine nucleotide analogs with human telomerase
-
Tendian, S. W., and Parker, W. B. (2000) Interaction of deoxyguanosine nucleotide analogs with human telomerase. Mol. Pharmacol. 57, 695-699 (Pubitemid 30183708)
-
(2000)
Molecular Pharmacology
, vol.57
, Issue.4
, pp. 695-699
-
-
Tendian, S.W.1
Parker, W.B.2
-
30
-
-
33746370368
-
Ribonucleotide reductases
-
DOI 10.1146/annurev.biochem.75.103004.142443
-
Nordlund, P., and Reichard, P. (2006) Ribonucleotide reductases. Annu. Rev. Biochem. 75, 681-706 (Pubitemid 44118048)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 681-706
-
-
Nordlund, P.1
Reichard, P.2
-
31
-
-
0020727826
-
Enzymic modification of a tyrosine residue to a stable free radical in ribonucleotide reductase
-
Barlow, T., Eliasson, R., Platz, A., Reichard, P., and Sjöberg, B-M. (1983) Enzymic modification of a tyrosine residue to a stable free radical in ribonucleotide reductase. Proc. Natl. Acad. Sci. USA 80, 1492-1495
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 1492-1495
-
-
Barlow, T.1
Eliasson, R.2
Platz, A.3
Reichard, P.4
Sjöberg, B.-M.5
-
32
-
-
0020541188
-
Ribonucleotide reducase - A radical enzyme
-
Reichard, P., and Ehrenberg, A. (1983) Ribonucleotide reducase - a radical enzyme. Science 221, 514-519
-
(1983)
Science
, vol.221
, pp. 514-519
-
-
Reichard, P.1
Ehrenberg, A.2
-
34
-
-
0019557717
-
Overproduction of the free radical of ribonucleotide reductase in hydroxyurea-resistant mouse cells
-
Åkerblom, L., Ehrenberg, A., Gräslund, A., Lankinen, H., Reichard, P., and Thelander, L. (1981) Overproduction of the free radical of ribonucleotide reductase in hydroxyurea-resistant mouse cells. Proc. Natl. Acad. Sci. USA 78, 2159-2163
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2159-2163
-
-
Åkerblom, L.1
Ehrenberg, A.2
Gräslund, A.3
Lankinen, H.4
Reichard, P.5
Thelander, L.6
-
35
-
-
0018395313
-
New ribonucleotide reductase inhibitors with antineoplastic activity
-
Elford, H. L., Wampler, G. L., and van't Riet, B. (1979) New ribonucleotide reductase inhibitors with antineoplastic activity. Cancer Res. 39, 844-851 (Pubitemid 9143275)
-
(1979)
Cancer Research
, vol.39
, Issue.3
, pp. 844-851
-
-
Elford, H.L.1
Wampler, G.L.2
Van 'T, R.B.3
|