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Volumn 18, Issue 11, 2012, Pages 2999-3001

Serum cholesterol and mTOR inhibitors: Surrogate biomarker or epiphenomenon?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CHOLESTEROL; EVEROLIMUS; LOW DENSITY LIPOPROTEIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TEMSIROLIMUS;

EID: 84861777925     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-0953     Document Type: Article
Times cited : (4)

References (12)
  • 1
    • 84861768887 scopus 로고    scopus 로고
    • Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus
    • Lee CK, Marschner IC, Simes J, Voysey M, Egleston BL, Hudes G, et al. Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus. Clin Cancer Res 2012;18:3188-96.
    • (2012) Clin Cancer Res , vol.18 , pp. 3188-3196
    • Lee, C.K.1    Marschner, I.C.2    Simes, J.3    Voysey, M.4    Egleston, B.L.5    Hudes, G.6
  • 3
    • 80053083941 scopus 로고    scopus 로고
    • The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile
    • Wang BT, Ducker GS, Barczak AJ, Barbeau R, Erle DJ, Shokat KM. The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile. Proc Natl Acad Sci U S A 2011;108: 15201-6.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 15201-15206
    • Wang, B.T.1    Ducker, G.S.2    Barczak, A.J.3    Barbeau, R.4    Erle, D.J.5    Shokat, K.M.6
  • 4
    • 48949115069 scopus 로고    scopus 로고
    • Rapamycin down-regulates LDL-receptor expression independently of SREBP-2
    • Sharpe LJ, Brown AJ. Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. Biochem Biophys Res Commun 2008;373:670-4.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 670-674
    • Sharpe, L.J.1    Brown, A.J.2
  • 8
    • 77951642773 scopus 로고    scopus 로고
    • Obesity, cholesterol, and clear-cell renal cell carcinoma (RCC)
    • Drabkin HA, Gemmill RM. Obesity, cholesterol, and clear-cell renal cell carcinoma (RCC). Adv Cancer Res 2010;107:39-56.
    • (2010) Adv Cancer Res , vol.107 , pp. 39-56
    • Drabkin, H.A.1    Gemmill, R.M.2
  • 10
    • 79955767772 scopus 로고    scopus 로고
    • Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib
    • Rini BI, Cohen DP, Lu DR, Chen I, Hariharan S, Gore ME, et al. Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst 2011;103: 763-73.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 763-773
    • Rini, B.I.1    Cohen, D.P.2    Lu, D.R.3    Chen, I.4    Hariharan, S.5    Gore, M.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.