Stem cell tourism in the era of personalized medicine: What we know, and what we need to know

Current Pharmacogenomics and Personalized Medicine

Volumn 10, Issue 2, 2012, Pages 106-110

  Master, Zubin ^a   Ogbogu, Ubaka ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Bioethics; Personalized medicine; Public perceptions; Stem cell research; Stem cell tourism

Indexed keywords

AUTISM; BLINDNESS; CEREBRAL PALSY; CHINA; COSTA RICA; EDITORIAL; EMBRYONIC STEM CELL; GENETIC SCREENING; GERMANY; HAIR LOSS; HEALTH INSURANCE; HUMAN; HUNGARY; NETHERLANDS; PARKINSON DISEASE; PATIENT EDUCATION; PERSONALIZED MEDICINE; PREMATURITY; REGULATORY MECHANISM; SPINAL CORD INJURY; SPORT INJURY; STEM CELL; STEM CELL RESEARCH; STEM CELL TRANSPLANTATION; UKRAINE;

EID: 84861750759     PISSN: 18756921     EISSN: 18756913     Source Type: Journal    
DOI: 10.2174/187569212800626340     Document Type: Editorial

References (56)

1. Caulfield T. Popular media, biotechnology, and the cycle of hype. Houston Journal of Health Law and Policy 2005; 213-33.
2. Master Z, Resnik DR. Hype and public trust in science. Sci Eng Ethics 2011; DOI 10.1007/s11948-011-9327-6.
3. Kitzinger J, Williams C. Forecasting science futures: Legitimising hope and calming fears in the embryo stem cell debate. Soc Sci Med 2005; 61(3): 731-40.
4. Dizikes P. Stem cell division. Salon May 11. 2009. Available from: http://www.salon.com/2009/05/11/stem_cell_politics/singleton/ [Accessed February 28, 2012].
5. Caulfield T. Stem cell research and economic promises. J Law Med Ethics 2010; 38(2): 303-13.
6. Caulfield T, Rachul C. Science spin: iPS cell research in the news. Clin Pharmacol Ther 2011; 89(5): 644-6.
7. Braude P, Minger SL, Warwick RM. Stem cell therapy: hope or hype? BMJ 2005; 330(7501): 1159-60.
8. Geesink I, Prainsack B, Franklin S. Stem cell stories 1998-2008. Sci Cult 2008; 17(1): 1-11.
9. Caulfield T. Do stem cells really offer a miracle cure? Huffington Post Canada, November 24, 2011. Available from: http://www. huffingtonpost.ca/timothy-caulfield/stem-celltherapy_b_1110237.html [Accessed February 28, 2012].
10. Knowles LP. Stem cell hype and the dangers of stem cell 'tourism'. Ethics White Paper for the Stem Cell Network. 2009. Available from: http://www.stemcellnetwork.ca/uploads/File/whitepapers/Stem-Cell-Hype.pdf [Accessed February 20, 2011].
11. Martell K, Trounson A, Baum E. Stem cell therapies in clinical trials: Workshop on best practices and the need for harmonization. Cell Stem Cell 2010; 7: 451-4.
12. Ryan KA, Sanders AM, Wang DD, et al. Tracking the rise of stem cell tourism. Regen Med 2010; 5(1): 27-33.
13. Dewitt ND, Yaffe, MP, Trounson, A. Beyond stem-cell genomics in California and beyond. Nat Biotechnol 2012; 30(1): 20-5.
14. Nagano K, Yoshida Y, Isobe T. Cell surface biomarkers of embryonic stem cells. Proteomics 2008; 8: 4025-35.
15. Caulfield T. Underwhelmed: hyperpole, regulatory policy, and the genetic revolution. McGill Law J 2000; 45: 437-60.
16. Burke W, Psaty BM. Personalized medicine in the era of genomics. JAMA 2007; 298(14): 1682-4.
17. Collier R. Separating hype from reality in the era of the affordable genome. CMAJ 2012; DOI:10.1503/cmaj.109-4143. Available from: http://www.cmaj.ca/site/earlyreleases/27feb12_separatinghype-from-reality-in-the-era-of-the-affordable-genome.xhtml [Accessed February 20, 2011].
18. Collier R. Popping the genomic bubble. CMAJ 2012; DOI:10. 1503/cmaj.109-4142. Available from: http://www.cmaj.ca/site/earlyreleases/28feb12_popping-the-genetics-bubble.xhtml [Accessed February 20, 2011].
19. Caulfield T. Predictive or preposterous? The marketing of DTC genetic testing. J Science Communication 2011; 10(3): 1-6.
20. Chen H, Gottweis H. Stem cell treatments in China: Rethinking the patient role in the global bio-economy. Bioethics 2011; doi: 10.1111/j.1467-8519.2011.01929.x.
21. Stem Cell Institute. Available from: http://www.cellmedicine.com/ [Accessed March 17, 2012].
22. EmCell. Available from: http://www.emcell.com/[Accessed March 17, 2012].
23. MEDRA Inc. Available from: http://www.medra.com/[Accessed March 17, 2012].
24. Lysaght T. Campbell A. Regulating autologous adult stem cells: the FDA steps up. Cell Stem Cell 2011; 9: 393-6.
25. von Tigerstrom B. The Food and Drug Administration, Regenerative Sciences, and the regulation of autologous stem cell therapies. Food Drug Law J 2011; 66: 479-506.
26. Lau D, Ogbogu U, Taylor B, et al. Stem cell clinics online: the direct-to-consumer portrayal of stem cell medicine. Cell Stem Cell 2008; 3: 591-4.
27. Zarzeczny A, Rachul C, Nisbet M, et al. Stem cell clinics in the news. Nat Biotechnol 2010; 28(12): 1243-6.
28. Carroll R. Costa Rican health ministry bans experimental stem cell treatment. Guardian UK, June 7, 2010. Available from: http://www.guardian.co.uk/world/2010/jun/07/costa-rica-stem-celltreatment [Accessed February 28, 2012].
29. Long C. Costa Rica's largest stem cell clinic closes. Tico Times, June 4, 2010. Available from: http://www.ticotimes.net/dailyarchive/2010_06/0604101.cfm [Accessed February 28, 2012].
30. Regenberg A, Hutchinson L, Schanker B, et al. Medicine on the Fringe: Stem Cell-Based Interventions in Advance of Evidence. Stem Cells 2009; 27: 2312-9.
31. Rachul C. "What have I got to lose?" An analysis of stem cell therapy patients' blogs. Health Law Rev 2011; 20(1): 5-12.
32. Tozer J. Blind girl can see again thanks to pioneering stem cell treatment. Daily Mail UK. March 5, 2009. Available from: http://www.dailymail.co.uk/health/article-1159209/Blind-girlthanks-pioneering-stem-cell-treatment.html [Accessed March 18, 2012].
33. Dobkin B, Curt A, Guest J. Cellular transplants in china: Observational study from the largest human experiment in chronic spinal cord injury. Neurorehabil Neural Repair 2006; 20(1): 5-13.
34. Amariglio N, Hirshberg A, Scheithauer BW, et al. Donor-derived brain tumor following neural stem cell transplantation in an Ataxia Telangiectasia patient. PLoS Med 2009; 6(2): e10000029. doi:10.1371/journal. pmed.1000029.
35. Miller N. Stem cell therapy sees man "infected" with cancer. WAToday. November 22, 2009. Available from: http://www. watoday.com.au/national/stem-cell-therapy-sees-man-infectedwith-cancer-20091123-itch.html [Accessed March 29, 2011].
36. Thirabanjasak D, Tantiwongse K, Thorner P. Angiomyeloproliferative lesions following autologous stem cell therapy. J Am Soc Nephrol 2010; 21, doi: 10.1681/ASN.2009111156.
37. Cyranoski D. Korean deaths spark inquiry. Nature 2010; 468: 485.
38. Mendick R, Palmer A. Baby death scandal at stem cell clinic which treats hundreds of British patients a year. The Telegraph. October 23, 2010. Available from: http://www.telegraph.co.uk/news/worldnews/europe/germany/8082935/Baby-death-scandal-at-stemcell-clinic-which-treats-hundreds-of-British-patients-a-year.html [Accessed March 23, 2011].
39. Mendick R, Hall A. Europe's largest stem cell clinic shut down after death of baby. The Telegraph May 8, 2011. Available from: http://www.telegraph.co.uk/news/worldnews/europe/germany/8500 233/Europes-largest-stem-cell-clinic-shut-down-after-death-ofbaby. html [Accessed 20 May 2011].
40. Vogel G. Authorities shut controversial German stem cell clinic. Science Insider May 10, 2011. Available from: http://news. sciencemag.org/scienceinsider/2011/05/authorities-shutcontroversial-g.html?rss=1 [Accessed 20 May 2011].
41. Einsiedel E, Adamson H. Stem cell tourism and future stem cell tourists: policy and ethical implications. Bioethics 2012; 12: 35-44.
42. Lindvall O, Hyun I. Medical innovation versus stem cell tourism. Science 2009; 324: 1664-5.
43. Cohen CB, Cohen PJ. International stem cell tourism and the need for effective regulation part I: stem cell tourism in Russia and India: clinical research, innovative treatment, or unproven hype? Kennedy Inst Ethics J 2010; 20: 27-49.
44. Caplan A, Levine P. Hope, hype, and help: ethically assessing the growing market in stem cell therapies. Am J Bioeth 2010; 10: 24-5.
45. Zarzeczny A, Caulfield T. Stem cell tourism and doctors' duties to minors-a view from Canada. Am J Bioeth 2010; 10: 3-15.
46. Master Z, Resnik DB. Stem-cell tourism and scientific responsibility. EMBO Rep 2011; 12(10): 992-5.
47. Sheldon T. Holland bans private stem cell clinic. BMJ 2007; 334: 12.
48. Stafford N. Germany tightens law on stem cell treatments. BMJ 2009; 339: b2967.
49. Than, K. Hungary detains 4 over illegal stem cell treatment. Reuters. July 29, 2009. Available from: http://www.reuters.com/article/2009/07/29/us-hungary-stemcellidUSTRE56S4PR20090729? pageNumber=1&virtualBrandChannel =0 [Accessed February 29, 2012].
50. International Society for Stem Cell Research. Patient Handbook on Stem Cell Therapies. December 3, 2008. Available from: http://www.isscr.org/clinical_trans/pdfs/ISSCRPatientHandbook.pd f [Accessed March 30, 2011].
51. Australian Stem Cell Centre. Stem Cell Therapies: Now and in the Future-The Australian Stem Cell Centre Patient Handbook. 2009; Available from: http://www.msnz.org.nz/Document.Doc?id=23 [Accessed November 10, 2011].
52. Stem Cell Network. Stem cell hype and the dangers of stem cell "tourism". Available from: http://www.stemcellnetwork.ca/index. php?page=stem-cell-hype-and-the-dangers-of-stem-cell-tourism [Accessed December 31, 2011].
53. Kovaleski SF. Baseball gets records on pitcher's procedure. The New York Times. July 13, 2011. Available from: http://www. nytimes.com/2011/07/14/sports/baseball/baseball-receives-recordson-bartolo-colonsstem-cell-procedure.html [Accessed February 29, 2012].
54. Red C. Peyton Manning's receiving stem cell therapy thrusts medical procedures back into sports spotlight. NY Daily News. September 18, 2011. Available from: http://www.nydailynews. com/sports/i-team/peyton-manning-receiving-stem-cell-therapy thrustsmedical-procedures-back-sports-spotlight-article-1.956042 [Accessed February 29, 2012].
55. Klemko R. Terrell Owens in South Korea for treatment. USA Today. September 20, 2011. Available from: http://content.usatoday. com/communities/thehuddle/post/2011/09/report-terrell-owens-insouth-korea-for-stem-cell-treatment/1 [Accessed March 16, 2012].
56. Saenz A. Texas Gov. Rick Perry received experimental stem cell therapy. ABC News. August 4, 2011. Available from: http://abcnews.go.com/Politics/texas-gov-rick-perry-receivedexperimental-stemcell/story?id=14232057 [Accessed February 29, 2012].