International stem cell tourism and the need for effective regulation: Part I: Stem cell tourism in Russia and India: Clinical research, innovative treatment, or unproven hype?

Kennedy Institute of Ethics Journal

Volumn 20, Issue 1, 2010, Pages 27-49

  Cohen, Cynthia B ^a   Cohen, Peter J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; EMBRYO RESEARCH; HEALTH CARE POLICY; HUMAN; INDIA; LEGAL ASPECT; MEDICAL RESEARCH; MEDICAL TOURISM; RUSSIAN FEDERATION; STEM CELL TRANSPLANTATION;

BIOMEDICAL RESEARCH; EMBRYO RESEARCH; HEALTH POLICY; HUMANS; INDIA; MEDICAL TOURISM; RUSSIA; STEM CELL TRANSPLANTATION;

EID: 77952822274     PISSN: 10546863     EISSN: 10863249     Source Type: Journal    
DOI: 10.1353/ken.0.0305     Document Type: Article

References (61)

1. Amariglio, Ninette; Hirshberg, Abraham; Scheithauer, Bernd W.; et al. 2009. Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient. PLoS Medicine 6: 221-231
2. Basu, Idrajit. 2005. India Embraces Stem Cell Research. Asia Times (2 December). Available at http://www.atimes.com/atimes/South-Asia/GL02Df02.html, accessed 23 February 2010.
3. Basu, Saionton. 2006. Regulating Stem Cell Research in India: Wedding the Public to the Policy. Current Science 90: 1476-1479
4. Biospectrum. 2007. BioNews: Parkinson's Conquered through Stem Cell Therapy. BioSpectrum (7 May). Available at http://biospectrumindia.ciol.com/ content/news/10705071.asp, accessed 23 February 2010.
5. Braude, Peter; Minger, Stephen; and Warwick, Ruth M. 2005. Stem Cell Therapy: Hope or Hype? British Medical Journal 330: 1159-1160
6. Chennai Online. 2010. Public Debate on Stem Cell Guidelines Soon. Chennai Online (17 January). Available at http://news.chennaionline.com/newsitem.aspx? NEWSID=62aab408-0113-4f80-829c-381f1e30f563&CATEGORYNAME=NATL, accessed 23 February 2010.
7. Cohen, Cynthia B. 2007. Renewing the Stuff of Life: Stem Cells, Ethics, and Public Policy New York: Oxford University Press.
8. Cohen, Peter J. 1998. The Placebo is not Dead: Three Historical Vignettes. IRB: A Review of Human Subjects Research 20 (2/3): 6-8.
9. Creasy, Graham, and Scott, Christopher Thomas. 2009. Stem Cell Transplants: The Power of Peer-to-Peer. Nature Biotechnology 27: 21-22.
10. Danilova, Maria. 2005. Craze for Stem Cell Therapy Spreads. SurgeryNews.Net (April). Available at http://surgerynews.net/news/2005/04/ stemcells0405-1.htm, accessed 27 February 2010.
11. Danishevski, Kirill, and McKee, Martin. 2005. Reforming the Russian Health Care System. Lancet 365: 1012-1014
12. Dimond, E. G.; Kittle, C. F.; and Crockett, J. E. 1960. Comparison of Internal Mammary Artery Ligation and Sham Operation for Angina Pectoris. American Journal of Cardiology 5: 483-486
13. DNA India. 2010. ICMR to Set Up Apex Committee to Regulate Stem Cell Research. DNA India (21 February). Available at http://www.dnaindia.com/india/ report-icmr-to-set-up-apex-committee-to-regulate-stem-cell-research-1350727, accessed 25 February, 2010.
14. EC-IC Bypass Study Group. 1985. Failure of Extracranial-Intracranial Arterial Bypass to Reduce the Risk of Ischemic Stroke. Results of an International Randomized Trial. New England Journal of Medicine 313: 1191-1200.
15. Enserink, Martin. 2006. Selling the Stem Cell Dream. Science 313: 160-163
16. Frew, Sarah E.; Kettler, Hannah E.; and Singer, Peter A. 2008. The Indian and Chinese Health Biotechnology Industries: Potential Champions of Global Health? Health Affairs 27: 1029-1041
17. Grammaticas, Damian. 2006. Stem Cell Promise Lures Patients. BBC News (11 January). Available at http://news.bbc.co.uk/1/hi/health/4603574.stm, accessed 23 February 2010.
18. Havlen, Naomi. 2007. Stem Cell Treatment Helps Boxtel Regain Strength. Aspen Times (23 August). Available at http://www.aspentimes.com/ar- ticle/20070823/NEWS/108230066, accessed 23 February 2010.
19. Inamdar, Maneesha. 2009. Update on Stem Cell Research - India 2009. Available at http://www.hescreg.eu/uploads/media/17.-Maneesha-Inamdar.pdf, accessed 23 February 2010.
20. Indian Council of Medical Research. Department of Biotechnology. 2007. Guidelines for Stem Cell Research and Therapy. Available at http://www.icmr.nic. in/stem-cell/Stem-cell-guidelines.pdf, accessed 23 February 2010.
21. Jayaraman, K. S. 2005. Indian Regulations Fail to Monitor Growing Stem-Cell Use in Clinics. Nature 434: 259.
22. Kahn, Jennifer. 2005. The Stem Cell Sell. New York Times (16 October). Available at http://www.nytimes.com/2005/10/16/style/tmagazine/t-b-2136-2141- stemce11-.html, accessed 23 February 2010.
23. Kiatpongsan, Sorapop, and Sipp, Douglas. 2009. Monitoring and Regulating Offshore Stem Cell Clinics. Science 323: 1564-1565
24. Khullar, Mridu. 2009. Unfettered by Regulation, India Pulls Ahead on Stem Cell Treatments. Global Post (9 October). Available at http://www.globalpost. com/dispatch/india/091009/unfettered-regulation-india-pulls-ahead-stem-cell- treatments, accessed 23 February 2010.
25. Kokurina, Yelena. 2007. "Water of Life" for the Business Class. Moscow News Weekly (18 November). No longer available online. A printed copy dated 12 March 2008 is available from the authors.
26. Kozlowski, Kim. 2007. More Travel Abroad for Stem Cell Therapy. Detroit News (29 November). Available at http://www.stemcellresearchformichigan.com/ media/news/TDN%2011-29-07.pdf, accessed 23 February 2010.
27. Kuznetsov, Vladimir. 2007. Some Background on the Russian Stem Cell Market. Russia Blog (25 June). Available at http://www.russiablog.org/2007/06/ investing-in-russia-background.php, accessed 23 February 2010.
28. Lander, Bryn; Thorsteinsdottir, Halia; Singer, Peter A.; and Daar, Abdullah S. 2008.Harnessing Stem Cells for Health Needs in India. Cell Stem Cell 3: 11-15.
29. Lanman, J. T. 1976. History of Oxygen Therapy and Retrolental Fibroplasia. (Prepared by the American Academy of Pediatrics, Committee on Fetus and Newborn.) Pediatrics 57 (supplement 2): 591-642.
30. Lau, Darren; Ogbogu, Ubaka; Taylor, Benjamin; et al. 2008. Stem Cell Clinics Online: The Direct-to-Consumer Portrayal of Stem Cell Medicine. Cell Stem Cell 3: 591-594
31. Lindvall, Olle, and Hyun, Insoo. 2009. Medical Innovation Versus Stem Cell Tourism. Science 324: 1664-1665
32. Loechler, Beth. 2008. Experimental Russian Stem Cell Treatments for Spinal Injury Credited for Woman's Progress. Grand Rapids Press (7 April). Available at http://www.neurovita.ru/pressa/eng-Kadi-DeHaan.html, accessed 23 February 2010.
33. MacReady, Norra. 2009. The Murky Ethics of Stem Cell Tourism. Lancet Oncology 10: 317-318
34. Mello, Michelle M., and Brennan, Troyen A. 2001. The Controversy Over High-Dose Chemotherapy with Autologous Bone Marrow Transplant for Breast Cancer. Health Affairs 20:101-117
35. Mudur, G. S. 2005. Stem Cell March, Minus Checks - Lack of Research Rules Allows Doctors to Do as They Like. Telegraph (16 November). Available at http://www.telegraphindia.com/1051117/asp/nation/story-5487047.asp,accessed 23 February 2010.
36. Mukherjee, Writankar. 2008. Corporate India Bets Big on Stem Cell. Economic Times (2 February). Available at http://economictimes.indiatimes.com/ article- show/2749782.cms, accessed 23 February 2010.
37. Murdoch, Charles E. and Scott, Christopher Thomas. Forthcoming. Stem Cell Tourism and the Power of Hope. American Journal of Bioethics.
38. National Commission. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. 1978. The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Available at http://www.hhs.gov/ohrphumansubjects/guidance/belmont. htm, accessed 23 February 2010.
39. National Institutes of Health. 2009. Stem Cell Information. Available at http://stemcells.nih.gov/info/health.asp,accessed 23 February 2010.
40. Osipova, Yulia. 2005. Stem Cells in the Cell: The Ministry of Health Intends to Close Clinics for People's Rejuvenation. Kommersant: Russia's Daily Online (1 April). Available at http://www.kommersant.com/page.asp?idr=1&id= 559557, accessed 23 February 2010.
41. Padma, T.V. 2005a. India Plans National Stem Cell Initiative. Science and Development Network (13 January). Available at http://www.scidev.net/en/news/ india-plans-national-stem-cell-initiative.html, accessed 23 February 2010.
42. -. 2005b. India Struggles to Regulate Biomedical Research. Science and Development Network (29 November). Available at http://www.scidev.net/en/news/ india-struggles-to-regulate-biomedical-research.html, accessed 23 February 2010.
43. -. 2005c. India Rivalry and Red Tape. Nature 436: 490-491
44. -. 2006. Unchecked by Guidelines, Indian Stem Cell Scientists Rush Ahead. Nature Medicine 12 (1): 4.
45. Parfitt, Tom. 2005. Russian Scientists Voice Concern over Stem-Cell Cosmetics. Lancet 365: 1219-1220
46. Pravda. 2005. Stem Cells' Popularity Triggers Fraud in Russian Medicine. Pravda. ru (17 March). Available at http://english.pravda.ru/science/19/94/377/ 15126-treatment.html, accessed 23 February 2010.
47. Ramesh, Randeep. 2005. Row over Doctor's "Miracle Cures." Guardian (18 November). Available at http://www.guardian.co.uk/science/2005/nov/ 18/stemcells.controversiesinscience, accessed 23 February 2010.
48. Rao, C. N. R. 2009. Science in the Future of India. Science 325: 126.
49. Regenberg, Alan C.; Hutchinson, Lauren A.; Schanker, Benjamin; and Mathews, Debra J. H. 2009. Medicine on the Fringe: Stem-Cell Based Interventions in Advance of Evidence. Stem Cells 27: 2312-2319
50. Ryan, Kirsten A.; Sanders, Amanda N.; Wang, Dong D.; and Levine, Aaron D. 2010. Tracking the Rise of Stem Cell Tourism. Regenerative Medicine 5: 27-33.
51. Sachitanand, N. N. 2009. Stem Cell Center to Rise in Biology Hub. Science 326: 1333.
52. Salter, Brian; Cooper, Melinda; Dickins, Amanda; and Cardo, Valentina. 2007. Stem Cell Science in India: Emerging Economies and the Politics of Globalization. Regenerative Medicine 2: 75-89.
53. Sharma, Alka. 2006. Stem Cell Research in India: Emerging Scenario and Policy Concerns. Asian Biotechnology and Development Review 8 (3): 43-53.
54. Singh, Jangveer. 2007. Stem Cell Therapy Cures Parkinson's Patient. Tribune, online edition (5 April). Available at http://www.tribuneindia.com/ 2007/20070405/main8.htm, accessed 23 February 2010.
55. Spooren, Annemie I. F.; Janssen-Potten, Yvonne J. M.; Snoek, Govert J.; et al. 2008. Rehabilitation Outcome of Upper Extremity Skilled Performance in Persons with Cervical Spinal Cord Injuries. Journal of Rehabilitation Medicine 40: 637-644
56. Srinivasan, Sandhya. 2006. Rogue Research in the Guise of Stem Cell Therapy. Infochange Health (March). Available at http://infochangeindia.org/ 20060302278/Health/Features/Rogue-research-in-the-guise-of-stem-cell-therapy. html, accessed 23 February 2010.
57. Svendsen, Clive. 2009. Stem Cell Clinical Trials Must Be Closely Monitored. Nature Reports Stem Cells (26 February). Available at http://www.nature.com/stemcells/2009/0902/090226/full/stemcells.2009.34.html, accessed 23 February 2010.
58. Titova, Nadya, and Brown, Frank. 2004. Stem Cell Rip-Off. Newsweek International (8 November). Available at http://www.encyclopedia.com/doc/1G1- 123981181.html, accessed 23 February 2010.
59. Tragakes, Ellie, and Lessof, Suszy. 2003. Russian Federation. In Health Care Systems in Transition, Vol.5, No.3, ed. Ellie Tragakes, pp. 27-44. Copenhagen: European Observatory on Health Systems and Policies.
60. UNI. 2006. Government to Act against Clinic Using Stem Cell Therapy. 2006. Hindu (23 January). Available at http://www.hindu.com/2006/01/23/stories/ 2006012300720900.htm, accessed 23 February 2010.
61. Wirth, Brigitte; van Hedel, Hubertus J. A.; Kometer, Barbara; et al. 2008. Changes in Activity after a Complete Spinal Cord Injury as Measured by the Spinal Cord Independence Measure II (SCIM II). Neurorehabilitation and Neural Repair 22: 145-153 (Pubitemid 351287599)