Synthesis and biological evaluation of novel indolyl isoxazoline derivatives as analgesic and antiinflammatory agents

Asian Journal of Chemistry

Volumn 24, Issue 6, 2012, Pages 2711-2716

  Chavan, R S ^a   Khadke, A P ^a  

^a PDEA's Seth Govind Raghunath Sable College of Pharmacy   (India)

Author keywords

Analgesic activity; Antiinflammatory; Indole; Isoxazoline; Ulcerogenesis

Indexed keywords

EID: 84861699086     PISSN: 09707077     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. D.A. Williams and T.L. Lemke, Foye's Principles of Medicinal Chemistry, Lippincott Williams and Wilkins, Philadelphia, p. 535 (1995).
2. K.D. Tripathi, Essential of Medical Pharmacology, Jaypee Brothers Medical Publishers (P) Ltd., edn. 6, pp. 184-185 (2008).
3. J.M. Scheiman, Clin. Update, 12, 1 (2005).
4. S. Fiorucci, L. Santucci and E. Distrutti, Dig. Liver Dis., 39, 1043 (2007).
5. D.C. Kosegarten, E.F. LaSala and S.F. Long, Comprehensive Pharmacy Review, Lippincott Williams and Wilkins, Philadelphia, pp. 289- 291 (2001).
6. M.R. Griffin, A. Yared and W.A. Ray, Am. J. Epidemiol., 151, 488(2000).
7. R.J. Flower, S. Moncada and J.R. Vane, Goodman and Gilman's The Pharmacological Basis of Therapeutics, McGrahill Medical Publishing Division, New York, edn. 7, p. 695 (1985).
8. M. Verma, V. Gujrati and M. Sharma, Arch. Pharm., 315, 358 (1982).
9. M. Bhalla,V. Srivastava, T. Bhalla and K. Shankar, Arzneim Forsch, 43, 595 (1993).
10. M. Verma, M. Tripathi and K. Shankar, Eur. J. Med. Chem., 29, 941 (1994).
11. U. Misra, A. Hitkari, A. Saxena and S. Gurtu, Eur. J. Med. Chem., 31, 629 (1996).
12. A. Andreani, M. Rambaldi, A. Locatelli and G. Pifferi, Eur. J. Med. Chem., 29, 903 (1994).
13. Y. Ebeid Mohamad, M. Lashine Sayed and M. El-Adl Sobhy, J. Pharm. Sci., 3, 40 (1994).
14. P. Rani, V.K. Srivastava and A. Kumar, Eur. J. Med. Chem., 39, 449 (2004).
15. A.G. Habeeb, P.N. Rao and E. Knaus, J. Med. Chem., 44, 2921 (2001).
16. M. Basappa, M.S. Kumar, S.N. Swamy, M. Mahendra and K.S. Rangappa, Bioorg. Med. Chem. Lett., 14, 3679 (2004).
17. G. Amgad, A.G. Habeeb, P. Rao and E.K. Edward, J. Med. Chem., 44, 2921 (2001).
18. S.A. Al-Issa and A.A. Hattab, J. Saudi Chem. Soc., 12, 537 (2008).
19. G. Dannhardt, W. Kiefer, G. Kramer, S. Maehrlein, U. Nowe and B. Fiebich, Eur. J. Med. Chem., 35, 499 (2000).
20. B. Shivkumar and L.V.G. Nargund, Indian J. Heterocycl. Chem., 8, 27 (1998).
21. B.S. Furniss, A.J. Hannaford and P.G. Smith, Vogel's Textbook of Practical Organic Chemistry, Longman Singapore Publisher Pvt. Ltd., edn. 5, p. 1161 (1996).
22. N. Rabjohn, Organic Synthesis Collective, John and Willey, Vol. 4, p. 539 (2005).
23. J. Desai, C. Desai and K. Desai, J. Iran. Chem. Soc., 5, 67 (2008).
24. C.A. Winter, E.A. Risley and C.W. Nuss, Proc. Soc. Exp. Biol. J., 3, 544 (1962).
25. R.A. Turner, Screening Methods Pharmacol., 1, 125 (1965).
26. H.O. Collier, L.C. Dinneen, C.A. Johnson and C. Schneider, Br. J. Pharmacol., 32, 295 (1968).
27. L.K. Leal, A.A. Ferreira, G.A. Bezerra and F.J. Matos, J. Ethnopharmacology, 70, 151 (2000).
28. V. Cioli, S. Putzolu, V. Rossi, B. Corza and C. Corradino, Toxicol. Appl. Pharmacol., 50, 283 (1979).