Calcium-sensing receptor mediates dietary peptide-induced CCK secretion in enteroendocrine STC-1 cells

Molecular Nutrition and Food Research

Volumn 56, Issue 5, 2012, Pages 753-760

  Nakajima, Shingo ^a   Hira, Tohru ^a   Hara, Hiroshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Calcium sensing receptor; Cholecystokinin; HEK 293 cells; Protein hydrolysate; STC 1 cells

Indexed keywords

4 AMINOBENZOIC ACID DERIVATIVE; 4 AMINOMETHYLBENZOIC ACID; 4-AMINOMETHYLBENZOIC ACID; AMINO ACID; BETA CONGLYCININ PROTEIN, GLYCINE MAX; BETA-CONGLYCININ PROTEIN, GLYCINE MAX; CALCIUM; CALCIUM SENSING RECEPTOR; CASEIN; CASR PROTEIN, HUMAN; CHOLECYSTOKININ; COTRANSPORTER; GLOBULIN; PEPTIDE FRAGMENT; PEPTIDE TRANSPORTER 1; PLANT ANTIGEN; PROTEIN HYDROLYSATE; SEED STORAGE PROTEIN; SOYBEAN PROTEIN;

ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENTEROENDOCRINE CELL; HUMAN; MEAT; METABOLISM; MOLECULAR WEIGHT; MOUSE; POTATO; PROTEIN INTAKE; SECRETION (PROCESS);

AMINO ACIDS; ANIMALS; ANTIGENS, PLANT; CALCIUM; CASEINS; CELLS, CULTURED; CHOLECYSTOKININ; DIETARY PROTEINS; ENTEROENDOCRINE CELLS; GLOBULINS; HUMANS; MEAT; MICE; MOLECULAR WEIGHT; PARA-AMINOBENZOATES; PEPTIDE FRAGMENTS; PROTEIN HYDROLYSATES; RECEPTORS, CALCIUM-SENSING; SEED STORAGE PROTEINS; SOLANUM TUBEROSUM; SOYBEAN PROTEINS; SYMPORTERS;

GLYCINE MAX; SOLANUM TUBEROSUM; VIGNA ANGULARIS;

EID: 84861676574     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100666     Document Type: Article

References (30)

1. Cummings, D. E., Overduin, J., Gastrointestinal regulation of food intake. J. Clin. Invest. 2007, 117, 13-23.
2. Parker, H. E., Reimann, F., Gribble, F. M., Molecular mechanisms underlying nutrient-stimulated incretin secretion. Expert. Rev. Mol. Med. 2010, 12, e1.
3. Wellendorph, P., Johansen, L. D., Bräuner-Osborne, H., Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients. Mol. Pharmacol. 2009, 76, 453-465.
4. Liddle, R. A., Cholecystokinin cells. Annu. Rev. Physiol. 1997, 59, 221-242.
5. Geraedts, M. C., Troost, F. J., Tinnemans, R., Söderholm, J. D. et al., Release of satiety hormones in response to specific dietary proteins is different between human and murine small intestinal mucosa. Ann. Nutr. Metab. 2010, 56, 308-313.
6. Nishi, T., Hara, H., Aoyama, Y., Guanidinated casein hydrolysate stimulation of cholecystokinin release via pancreatic enzyme- and cholinergic-independent mechanisms in rats. Biosci. Biotechnol. Biochem. 1999, 63, 1070-1074.
7. Liou, A. P., Chavez, D. I., Espero, E., Hao, S. et al., Protein hydrolysate-induced cholecystokinin secretion from enteroendocrine cells is indirectly mediated by the intestinal oligopeptide transporter PepT1. Am. J. Physiol. Gastrointest Liver Physiol. 2011, 300, G895-G902.
8. Liou, A. P., Sei, Y., Zhao, X., Feng, J. et al., The extracellular calcium sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells. Am. J. Physiol. Gastrointest Liver Physiol. 2011, 300, G538-G546.
9. McLaughlin J. T., Lomax, R. B., Hall, L., Dockray, G. J. T. et al., Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1. J. Physiol. 1998, 513, 11-18.
10. Brown, E. M., Gamba, G., Riccardi, D., Lombardi, M. et al., Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 1993, 366, 575-580.
11. Conigrave, A. D., Quinn, S. J., Brown, E. M., L-amino acid sensing by the extracellular Ca2+-sensing receptor. Proc. Natl. Acad. Sci. USA 2000, 97, 4814-4819.
12. Cheng, S. X., Geibel, J. P., Hebert, S. C., Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor. Gastroenterology 2004, 126, 148-158.
13. Quinn, S. J., Ye, C. P., Diaz, R., Kifor, O. et al., The Ca2+-sensing receptor: a target for polyamines. Am. J. Physiol. 1997, 273, C1315-C1323.
14. Gama, L., Baxendale-Cox, L. M., Breitwieser, G. E., Ca2+-sensing receptors in intestinal epithelium. Am. J. Physiol. 1997, 273, C1168-C1175.
15. Malaisse, W. J., Louchami, K., Laghmich, A., Ladrière, L. et al., Possible participation of an islet B-cell calcium-sensing receptor in insulin release. J. Endocrinol. 1999, 11, 293-300.
16. Wang, Y., Chandra, R., Samsa, L. A., Gooch, B. et al., Amino acids stimulate cholecystokinin release through the calcium-sensing receptor. Am. J. Physiol. Gastrointest Liver Physiol. 2011, 300, G528-G537.
17. Mangel, A. W., Prpic, V., Wong, H., Basavappa, S. et al. Phenylalanine-stimulated secretion of cholecystokinin is calcium dependent. Am. J. Physiol. 1995, 268, G90-G94.
18. Hira, T., Nakajima, S., Eto, Y., Hara, H., Calcium-sensing receptor mediates phenylalanine-induced cholecystokinin secretion in enteroendocrine STC-1 cells. FEBS J. 2008, 275, 4620-4626.
19. Nakajima, S., Hira, T., Eto, Y., Asano, K., Hara, H., Soybean beta 51-63 peptide stimulates cholecystokinin secretion via a calcium-sensing receptor in enteroendocrine STC-1 cells. Regul. Pept. 2010, 159, 148-155.
20. Ohsu, T., Amino, Y., Nagasaki, H., Yamanaka, T. et al., Involvement of the calcium-sensing receptor in human taste perception. J. Biol. Chem. 2010, 285, 1016-1022.
21. Rybczynska, A., Lehmann, A., Jurska-Jasko, A., Boblewski, K. et al., Hypertensive effect of calcilytic NPS 2143 administration in rats. J. Endocrinol. 2006, 191, 189-195.
22. Nishi, T., Hara, H., Hira, T., Tomita, F., Dietary protein peptic hydrolysates stimulate cholecystokinin release via direct sensing by rat intestinal mucosal cells. Exp. Biol. Med. (Maywood) 2001, 226, 1031-1036.
23. Cohen, S. A., Bidlingmeyer, B. A., Tarvin, T. L. 2288; PITC derivatives in amino acid analysis. Nature 1986, 320, 769-770.
24. Darcel, N. P., Liou, A. P., Tomé, D., Raybould, H. E., Activation of vagal afferents in the rat duodenum by protein digests requires PepT1. J. Nutr. 2005, 135, 1491-1495.
25. Matsumura, K., Miki, T., Jhomori, T., Gonoi, T., Seino, S., Possible role of PEPT1 in gastrointestinal hormone secretion. Biochem. Biophys. Res. Commun. 2005, 336, 1028-1032.
26. Choi, S., Lee, M., Shiu, A. L., Yo, S. J. et al., GPR93 activation by protein hydrolysate induces CCK transcription and secretion in STC-1 cells. Am. J. Physiol. Gastrointest Liver Physiol. 2007, 292, G1366-G1375.
27. Ray, K., Northup, J., Evidence for distinct cation and calcimimetic compound (NPS 568) recognition domains in the transmembrane regions of the human Ca2+ receptor. J. Biol. Chem. 2002, 277, 18908-18913.
28. Cordier-Bussat, M., Bernard, C., Haouche, S., Roche, C. et al., Peptones stimulate cholecystokinin secretion and gene transcription in the intestinal cell line STC-1. Endocrinology 1997, 138, 1137-1144.
29. Geibel, J. P., Hebert, S. C., The functions and roles of the extracellular Ca2+-sensing receptor along the gastrointestinal tract. Annu. Rev. Physiol. 2009, 71, 205-217.
30. Feng, J., Petersen, C. D., Coy, D. H., Jiang, J. K. et al., Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion. Proc. Natl. Acad. Sci. USA 2010, 107, 17791-17796.