메뉴 건너뛰기




Volumn 21, Issue 2, 2012, Pages 379-392

Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha

Author keywords

Biomarkers; Cyto genotoxicity; Dreissena polymorpha; Mixture; Non steroidal anti inflammatory drugs (NSAIDs)

Indexed keywords

CATALASE; DICLOFENAC; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; IBUPROFEN; PARACETAMOL; SUPEROXIDE DISMUTASE; FRESH WATER; MUTAGENIC AGENT; NEUTRAL RED; NONSTEROID ANTIINFLAMMATORY AGENT; OXIDOREDUCTASE;

EID: 84861674641     PISSN: 09639292     EISSN: 15733017     Source Type: Journal    
DOI: 10.1007/s10646-011-0799-6     Document Type: Article
Times cited : (68)

References (64)
  • 1
    • 0035328829 scopus 로고    scopus 로고
    • CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk
    • Bigler J, Whitton J, Lampe JW, Fosdick L, Bostick RM, Potter JD (2001) CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. Cancer Res 61: 3566-3569
    • (2001) Cancer Res , vol.61 , pp. 3566-3569
    • Bigler, J.1    Whitton, J.2    Lampe, J.W.3    Fosdick, L.4    Bostick, R.M.5    Potter, J.D.6
  • 2
    • 27644595338 scopus 로고    scopus 로고
    • Screening of POP pollution by AChE and EROD activities in zebra musselsfrom the Italian great lakes
    • doi: 10.1016/j.chemosphere.2005.03.047
    • Binelli A, Ricciardi F, Riva C, Provini A (2005) Screening of POP pollution by AChE and EROD activities in zebra musselsfrom the Italian great lakes. Chemosphere 61: 1074-1082. doi: 10.1016/j.chemosphere.2005.03.047
    • (2005) Chemosphere , vol.61 , pp. 1074-1082
    • Binelli, A.1    Ricciardi, F.2    Riva, C.3    Provini, A.4
  • 5
    • 67650747332 scopus 로고    scopus 로고
    • A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism Zebra mussel (Dreissena polymorpha)
    • doi: 10.1016/j.cbpc.2009.05.011
    • Binelli A, Parolini M, Cogni D, Pedriali A, Provini A (2009b) A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism Zebra mussel (Dreissena polymorpha). Comp Biochem Physiol C 150: 329-336. doi: 10.1016/j.cbpc.2009.05.011
    • (2009) Comp Biochem Physiol C , vol.150 , pp. 329-336
    • Binelli, A.1    Parolini, M.2    Cogni, D.3    Pedriali, A.4    Provini, A.5
  • 6
    • 0029923268 scopus 로고    scopus 로고
    • DNA strand breakage in freshwater mussels (Anodonta grandis) exposed to lead in the laboratory and field
    • doi: 10.1002/etc.5620150528
    • Black MC, Ferrell JR, Horning RC, Martin LK Jr (1996) DNA strand breakage in freshwater mussels (Anodonta grandis) exposed to lead in the laboratory and field. Environ Toxicol Chem 15: 802-808. doi: 10.1002/etc.5620150528
    • (1996) Environ Toxicol Chem , vol.15 , pp. 802-808
    • Black, M.C.1    Ferrell, J.R.2    Horning, R.C.3    Martin Jr., L.K.4
  • 7
    • 33746612291 scopus 로고    scopus 로고
    • Predicted and measured concentrations for selected pharmaceuticals in UK rivers: Implications for risk assessment
    • doi: 10.1016/j.watres. 2006.05.036
    • Bound JB, Voulvoulis N (2006) Predicted and measured concentrations for selected pharmaceuticals in UK rivers: implications for risk assessment. Water Res 40: 2885-2892. doi: 10.1016/j.watres. 2006.05.036
    • (2006) Water Res , vol.40 , pp. 2885-2892
    • Bound, J.B.1    Voulvoulis, N.2
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding. Anal Biochem 72: 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0038396291 scopus 로고    scopus 로고
    • Effects of temperature on baseline and genotoxicant-induced DNA damage in haemocytes of Dreissena polymorpha
    • doi: 10.1016/S1383-5718 (03)00050
    • Buschini A, Carboni P, Martino A, Poli P, Rossi C (2003) Effects of temperature on baseline and genotoxicant-induced DNA damage in haemocytes of Dreissena polymorpha. Mutat Res 537: 81-92. doi: 10.1016/S1383-5718 (03)00050
    • (2003) Mutat Res , vol.537 , pp. 81-92
    • Buschini, A.1    Carboni, P.2    Martino, A.3    Poli, P.4    Rossi, C.5
  • 10
    • 45449087504 scopus 로고    scopus 로고
    • Comparison of predicted and measured concentrations of selected pharmaceuticals, fragrances and hormones in Spanish sewage
    • doi: 10.1016/j.chemosphere.2008.04.03
    • Carballa M, Omil F, Lema JM (2008) Comparison of predicted and measured concentrations of selected pharmaceuticals, fragrances and hormones in Spanish sewage. Chemosphere 72: 118-1123. doi: 10.1016/j.chemosphere.2008.04.03
    • (2008) Chemosphere , vol.72 , pp. 118-1123
    • Carballa, M.1    Omil, F.2    Lema, J.M.3
  • 11
    • 2942744630 scopus 로고    scopus 로고
    • A comparative study of the expression of CYP1A and CYP4 genes in aquatic invertebrate (freshwater mussel, Unio tumidus) and vertebrate (rainbow trout, Oncorhynchus mykiss)
    • 10.1016/ j.aquatox.2004.04.01
    • Chaty S, Rodius F, Vasseur P (2004) A comparative study of the expression of CYP1A and CYP4 genes in aquatic invertebrate (freshwater mussel, Unio tumidus) and vertebrate (rainbow trout, Oncorhynchus mykiss). Aquat Toxicol 69: 81-93. doi: 10.1016/ j.aquatox.2004.04.01
    • (2004) Aquat Toxicol 69 , pp. 81-93
    • Chaty, S.1    Rodius, F.2    Vasseur, P.3
  • 12
    • 0034883890 scopus 로고    scopus 로고
    • DNA adduct formation and DNA strand breaks in green-lipped mussels (Perna viridis) exposed to benzo[a]pyrene: Dose- and time-dependent relationships
    • doi: S0025-326X0000209-215
    • Ching EWK, Siu WHL, Lam PKS, Xu L, Zhang Y, Richardson BJ, Wu RSS (2001) DNA adduct formation and DNA strand breaks in green-lipped mussels (Perna viridis) exposed to benzo[a]pyrene: dose- and time-dependent relationships. Mar Pollut Bull 42: 603-610. doi: S0025-326X (00)00209-5
    • (2001) Mar Pollut Bull 42 , vol.603-610
    • Ewk, C.1    Whl, S.2    Pks, L.3    Xu, L.4    Zhang, Y.5    Richardson, B.J.6    Rss, W.7
  • 13
    • 0037447779 scopus 로고    scopus 로고
    • Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects
    • doi: 10.1016/S0378-4274
    • Cleuvers M (2003) Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects. Toxicol Lett 142: 185- 194. doi: 10.1016/S0378-4274 (03)00068-7
    • (2003) Toxicol Lett 142 , vol.185-194 , Issue.3 , pp. 00068-77
    • Cleuvers, M.1
  • 14
    • 1642393941 scopus 로고    scopus 로고
    • Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen and acetylsalicylic acid
    • doi: 10.1016/S0147-6513
    • Cleuvers M (2004) Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen and acetylsalicylic acid. Ecotoxicol Environ Saf 59: 309-315. doi: 10.1016/S0147-6513 (03) 00141-6
    • (2004) Ecotoxicol Environ Saf 59 , vol.309-315 , Issue.3 , pp. 00141-00146
    • Cleuvers, M.1
  • 15
    • 33751408495 scopus 로고    scopus 로고
    • Heavy metal contamination and antioxidant response of a freshwater bryozoan (Lophopus crystallinus., Pall Phylactolaemata)
    • doi: 10.1016/j.ecoenv.2005.12.004
    • Elia AC, Galarini R, Dorra AJM, Taticchi MI (2007) Heavy metal contamination and antioxidant response of a freshwater bryozoan (Lophopus crystallinus., Pall Phylactolaemata). Ecotoxicol Environ Saf 66: 188-194. doi: 10.1016/j.ecoenv.2005.12.004
    • (2007) Ecotoxicol Environ Saf , vol.66 , pp. 188-194
    • Elia, A.C.1    Galarini, R.2    Ajm, D.3    Taticchi, M.I.4
  • 16
    • 18344384131 scopus 로고    scopus 로고
    • Vitro assessment of modes of toxic action of pharmaceuticals in aquatic life
    • doi: 10.1021/es048590e
    • Escher BI, Bramaz N, Eggen RIL, RichterM (2005) In vitro assessment of modes of toxic action of pharmaceuticals in aquatic life. Environ Sci Technol 39: 3090-3100. doi: 10.1021/es048590e
    • (2005) Environ Sci Technol , vol.39 , pp. 3090-3100
    • Escher, B.I.1    Bramaz, N.2    Ril, E.3    Richter, M.4
  • 17
    • 30644479441 scopus 로고    scopus 로고
    • Ecotoxicology of human pharmaceuticals
    • 10.1016/ j.aquatox.2006.02.006
    • Fent K, Weston AA, Caminada D (2006) Ecotoxicology of human pharmaceuticals. Aquat Toxicol 76: 122-159. doi: 10.1016/ j.aquatox.2006.02.006
    • (2006) Aquat Toxicol 76 , pp. 122-159
    • Fent, K.1    Weston, A.A.2    Caminada, D.3
  • 18
    • 0038544203 scopus 로고    scopus 로고
    • Ecotoxicological impact of pharmaceuticals found in treated waste waters: Study of carbamazepine, clofibric acid and diclofenac
    • doi: 10.1016/S0147- 6513 (03)00111-8
    • Ferrari B, Paxeus N, Lo Giudice R, Pollio A, Garric J (2003) Ecotoxicological impact of pharmaceuticals found in treated waste waters: study of carbamazepine, clofibric acid and diclofenac. Ecotoxicol Environ Saf 55: 359-370. doi: 10.1016/S0147- 6513 (03)00111-8
    • (2003) Ecotoxicol Environ Saf , vol.55 , pp. 359-370
    • Ferrari, B.1    Paxeus, N.2    Lo Giudice, R.3    Pollio, A.4    Garric, J.5
  • 19
    • 24944520001 scopus 로고    scopus 로고
    • Effects of pharmaceuticals on Daphnia survival, growth, and reproduction
    • doi: 10.1016/j.chemosphere.2005.02.016
    • Flaherty CM, Dodson SI (2005) Effects of pharmaceuticals on Daphnia survival, growth, and reproduction. Chemosphere 61: 200-207. doi: 10.1016/j.chemosphere.2005.02.016
    • (2005) Chemosphere , vol.61 , pp. 200-207
    • Flaherty, C.M.1    Dodson, S.I.2
  • 20
    • 0028830109 scopus 로고
    • Expression and selective inhibition of the constitutive and inducible forms of human cyclooxygenase
    • Gierse JK, Hauser SD, Creely DP, Koboldt C, Rangwala SH, Isakson PC et al (1995) Expression and selective inhibition of the constitutive and inducible forms of human cyclooxygenase. Biochem J 305: 479-484
    • (1995) Biochem J , vol.305 , pp. 479-484
    • Gierse, J.K.1    Hauser, S.D.2    Creely, D.P.3    Koboldt, C.4    Rangwala, S.H.5    Isakson, P.C.6
  • 22
    • 51249095222 scopus 로고    scopus 로고
    • Environmental assessment of Norweigian priority pharmaceuticals based on the EMEA guideline
    • doi: 10.1016/j.ecoenv.2007.10.015
    • Grung M, Kallqvist T, Sakshaug S, Skurtveit S, Thomas V (2008) Environmental assessment of Norweigian priority pharmaceuticals based on the EMEA guideline. Ecotoxicol Environ Saf 71: 328-340. doi: 10.1016/j.ecoenv.2007. 10.015
    • (2008) Ecotoxicol Environ Saf , vol.71 , pp. 328-340
    • Grung, M.1    Kallqvist, T.2    Sakshaug, S.3    Skurtveit, S.4    Thomas, V.5
  • 23
    • 29744441163 scopus 로고    scopus 로고
    • Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: Occurrence and toxicity to Daphnia magna
    • doi: 10.1897/05-193R.1
    • Han GH, Hur HG, Kim SD (2006) Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: occurrence and toxicity to Daphnia magna. Environ Toxicol Chem 25: 265-271. doi: 10.1897/05-193R.1
    • (2006) Environ Toxicol Chem , vol.25 , pp. 265-271
    • Han, G.H.1    Hur, H.G.2    Kim, S.D.3
  • 24
    • 12844268268 scopus 로고    scopus 로고
    • Glutathione transferases doi: 10.1146/annurev. pharmtox.45.120403.095857
    • Hayes JD, Flanagan JU, Jowsey IR (2005) Glutathione transferases. Annu Rev Pharmacol Toxicol 45: 51-88. doi: 10.1146/annurev. pharmtox.45.120403.095857
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 51-88
    • Hayes, J.D.1    Flanagan, J.U.2    Jowsey, I.R.3
  • 25
    • 34547538239 scopus 로고    scopus 로고
    • Chronic toxicity of ibuprofen to Daphnia magna: Effects on life history traits and population dynamics
    • doi: 10.1016/j.toxlet. 2007.06.001
    • Heckmann LH, Callaghan A, Hooper HL, Connon R, Hutchinson TH, Maund SJ, Sibly RM (2007) Chronic toxicity of ibuprofen to Daphnia magna: effects on life history traits and population dynamics. Toxicol Lett 172: 137-145. doi: 10.1016/j.toxlet. 2007.06.001
    • (2007) Toxicol Lett , vol.172 , pp. 137-145
    • Heckmann, L.H.1    Callaghan, A.2    Hooper, H.L.3    Connon, R.4    Hutchinson, T.H.5    Maund, S.J.6    Sibly, R.M.7
  • 26
    • 33947302739 scopus 로고    scopus 로고
    • Analysis of the effects diclofenac has on Japanese medaka (Oryzias latipes) using real-time PCR
    • 10.1016/ j.chemosphere.2006.12.090
    • Hong HN, Kim HN, Park KS, Lee SK, Gu MB (2007) Analysis of the effects diclofenac has on Japanese medaka (Oryzias latipes) using real-time PCR. Chemosphere 67: 2115-2121. doi: 10.1016/ j.chemosphere.2006.12.090
    • (2007) Chemosphere 67 , pp. 2115-2121
    • Hong, H.N.1    Kim, H.N.2    Park, K.S.3    Lee, S.K.4    Gu, M.B.5
  • 27
    • 61349108031 scopus 로고    scopus 로고
    • Metabolism of acetaminophen (paracetamol) in plants-two independent pathways result in the formation of a glutathione and a glucose conjugate
    • doi: 10.1007/ s11356-008-0095-
    • Huber C, Bartha B, Harpaintner R, Schröder P (2009) Metabolism of acetaminophen (paracetamol) in plants-two independent pathways result in the formation of a glutathione and a glucose conjugate. Environ Sci Pollut Res 16: 206-213. doi: 10.1007/ s11356-008-0095-
    • (2009) Environ Sci Pollut Res , vol.16 , pp. 206-213
    • Huber, C.1    Bartha, B.2    Harpaintner, R.3    Schröder, P.4
  • 28
    • 33646925337 scopus 로고    scopus 로고
    • Pain control: Non-steroidal anti-inflammatory agents
    • doi: 10.1016/j.siny.2006.02.009
    • Jacqz-Aigrain E, Anderson BJ (2006) Pain control: non-steroidal anti-inflammatory agents. Semin Fetal Neonat M 11: 251-256. doi: 10.1016/j.siny.2006.02.009
    • (2006) Semin Fetal Neonat M , vol.11 , pp. 251-256
    • Jacqz-Aigrain, E.1    Anderson, B.J.2
  • 29
    • 53649084556 scopus 로고    scopus 로고
    • The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK
    • doi: 10.1016/j.watres.2008.04.026
    • Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ (2008) The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water Res 42 (13): 3498-3518. doi: 10.1016/j.watres.2008.04.026
    • (2008) Water Res , vol.42 , Issue.13 , pp. 3498-3518
    • Kasprzyk-Hordern, B.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 30
    • 7044264982 scopus 로고    scopus 로고
    • Effects of some environmental parameters on catalase activity measured in the mussel (Mytilus galloprovincialis) exposed to lindane
    • doi: 10.1016/j.envpol.2004.05.035
    • Khessiba A, Romeo M, Aïssa P (2005) Effects of some environmental parameters on catalase activity measured in the mussel (Mytilus galloprovincialis) exposed to lindane. Environ Pollut 133: 275-281. doi: 10.1016/j.envpol.2004.05.035
    • (2005) Environ Pollut , vol.133 , pp. 275-281
    • Khessiba, A.1    Romeo, M.2    Aïssa, P.3
  • 33
    • 0033065918 scopus 로고    scopus 로고
    • Epidemiology of non-steroidal anti-inflammatory drug damage to stomach and duodenum
    • Langman MJS (1999) Epidemiology of non-steroidal anti-inflammatory drug damage to stomach and duodenum. Ital J Gastroenterol Hepatol 31 (S1): 2-5
    • (1999) Ital J Gastroenterol Hepatol , vol.31 , Issue.S1 , pp. 2-5
    • Mjs, L.1
  • 34
    • 0028072760 scopus 로고
    • Contaminant induced lysosomal membrane damage in marine mussel digestive cells-an in vitro study
    • Lowe DM, Pipe RK (1994) Contaminant induced lysosomal membrane damage in marine mussel digestive cells-an in vitro study. Aquat Toxicol 30: 357-365
    • (1994) Aquat Toxicol , vol.30 , pp. 357-365
    • Lowe, D.M.1    Pipe, R.K.2
  • 35
    • 0002836010 scopus 로고
    • Contaminant impact on interactions of molecular probes with lysosomes in living hepatocytes from dab Limanda limanda
    • Lowe DM, Moore MN, Evans BM (1992) Contaminant impact on interactions of molecular probes with lysosomes in living hepatocytes from dab Limanda limanda. Mar Ecol Prog Ser 91: 135-140
    • (1992) Mar Ecol Prog ser , vol.91 , pp. 135-140
    • Lowe, D.M.1    Moore, M.N.2    Evans, B.M.3
  • 36
    • 0029505136 scopus 로고
    • Contaminant-induced lysosomal membrane damage in blood cells of mussels Mytilus galloprovincialis from the Venice Lagoon: An in vitro study
    • Lowe DM, Fossato VU, Depledge MH (1995) Contaminant-induced lysosomal membrane damage in blood cells of mussels Mytilus galloprovincialis from the Venice Lagoon: an in vitro study. Mar Ecol Prog 129: 189-196
    • (1995) Mar Ecol Prog , vol.129 , pp. 189-196
    • Lowe, D.M.1    Fossato, V.U.2    Depledge, M.H.3
  • 37
    • 26844550239 scopus 로고    scopus 로고
    • The neutral red lysosomal retention assay and Comet assay on haemolymph cells from mussels (Mytilus edulis) and fish (Symphodus melops) exposed to styrene
    • doi: 10.1016/j.aquatox. 2005.08.001
    • Mamaca E, Bechmann RK, Torgrimsen S, Aas E, Bjornstad A, Baussant T, Le Floch S (2005) The neutral red lysosomal retention assay and Comet assay on haemolymph cells from mussels (Mytilus edulis) and fish (Symphodus melops) exposed to styrene. Aquat Toxicol 75: 191-201. doi: 10.1016/j.aquatox. 2005.08.001
    • (2005) Aquat Toxicol , vol.75 , pp. 191-201
    • Mamaca, E.1    Bechmann, R.K.2    Torgrimsen, S.3    Aas, E.4    Bjornstad, A.5    Baussant, T.6    Le Floch, S.7
  • 38
    • 0005590750 scopus 로고    scopus 로고
    • Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
    • doi: 10.1067/mcp.2000.104736-S0009-9236
    • Maniyke PT, Kharasch ED, Kalhorn TF, Slattery JT (2000) Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation. Clin Pharmacol Ther 67: 275-281. doi: 10.1067/mcp.2000.104736-S0009-9236 (00)56394-2
    • (2000) Clin Pharmacol Ther 67 , vol.275-281 , Issue.0 , pp. 56394-56402
    • Maniyke, P.T.1    Kharasch, E.D.2    Kalhorn, T.F.3    Slattery, J.T.4
  • 39
    • 0023906723 scopus 로고
    • Use of Gammarus pulex (L.) in safety evaluation tests: Culture and selection of a sensitive life stage
    • McCahon CP, Pascoe D (1988) Use of Gammarus pulex (L.) in safety evaluation tests: culture and selection of a sensitive life stage. Ecotoxicol Environ Saf 15: 245-252
    • (1988) Ecotoxicol Environ Saf , vol.15 , pp. 245-252
    • McCahon, C.P.1    Pascoe, D.2
  • 40
    • 77949392061 scopus 로고    scopus 로고
    • Uptake and biological effects of environmentally relevant concentrations of the nonsteroidal anti-inflammatory pharmaceutical diclofenac in rainbow trout (Oncorhynchus mykiss)
    • doi: 10.1021/es903702m
    • Mehinto A, Hill E, Tyler C (2010) Uptake and biological effects of environmentally relevant concentrations of the nonsteroidal anti-inflammatory pharmaceutical diclofenac in rainbow trout (Oncorhynchus mykiss). Environ Sci Technol 44: 2176-2182. doi: 10.1021/es903702m
    • (2010) Environ Sci Technol , vol.44 , pp. 2176-2182
    • Mehinto, A.1    Hill, E.2    Tyler, C.3
  • 41
    • 0025493883 scopus 로고
    • Effects of commonly used non steroidal anti-inflammatory drugs on gastric mucosa. A clinical, endoscopic and histopathological study
    • Misra R, Pandey H, Chandra M, Agarwal PK, Pandeya SN (1990) Effects of commonly used non steroidal anti-inflammatory drugs on gastric mucosa. A clinical, endoscopic and histopathological study. J Assoc Phys India 38 (9): 636-638
    • (1990) J Assoc Phys India , vol.38 , Issue.9 , pp. 636-638
    • Misra, R.1    Pandey, H.2    Chandra, M.3    Agarwal, P.K.4    Pandeya, S.N.5
  • 42
    • 0001361067 scopus 로고    scopus 로고
    • Detection of DNA strand breaks in brown trout (Salmo trutta) hepatocytes and blood cells using the single cell gel electrophoresis (comet) assay
    • doi: 10.1016/S0166-445X
    • Mitchelmore CL, Chipman JK (1998) Detection of DNA strand breaks in brown trout (Salmo trutta) hepatocytes and blood cells using the single cell gel electrophoresis (comet) assay. Aquat Toxicol 41: 161-182. doi: 10.1016/S0166-445X (97)00064-7
    • (1998) Aquat Toxicol 41 , vol.161-182 , Issue.97 , pp. 00064-00067
    • Mitchelmore, C.L.1    Chipman, J.K.2
  • 43
    • 34247602015 scopus 로고    scopus 로고
    • Comparison of key enzymes in the zebra mussel, Dreissena polymorpha, the earthworm Allolobophora chlorotica and Chironomus riparius larvae
    • doi: 10.1016/j.ecoenv.2006.05.003
    • Osman AM, van Noort PCM (2007) Comparison of key enzymes in the zebra mussel, Dreissena polymorpha, the earthworm Allolobophora chlorotica and Chironomus riparius larvae. Ecotoxicol Environ Saf 67: 212-217. doi: 10.1016/j.ecoenv.2006.05.003
    • (2007) Ecotoxicol Environ Saf , vol.67 , pp. 212-217
    • Osman, A.M.1    Van Noort Pcm2
  • 44
    • 77949489157 scopus 로고    scopus 로고
    • Multi-biomarker approach for the evaluation of the cyto-genotoxicity of paracetamol on the zebra mussel (Dreissena polymorpha)
    • doi: 10.1016/j.chemosphere.2010.02.053
    • Parolini M, Binelli A, Cogni D, Provini A (2010) Multi-biomarker approach for the evaluation of the cyto-genotoxicity of paracetamol on the zebra mussel (Dreissena polymorpha). Chemosphere 79: 489-498. doi: 10.1016/j.chemosphere. 2010.02.053
    • (2010) Chemosphere , vol.79 , pp. 489-498
    • Parolini, M.1    Binelli, A.2    Cogni, D.3    Provini, A.4
  • 45
    • 79955059977 scopus 로고    scopus 로고
    • Assessment of the potential cyto-genotoxicity of the nonsteroidal anti-inflammatory drug (NSAID
    • doi: 10.1007/s11270- 010
    • Parolini M, Binelli A, Provini A (2011a) Assessment of the potential cyto-genotoxicity of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac on the zebra mussel (Dreissena polymorpha). Water Air Soil Pollut 217: 589-601. doi: 10.1007/s11270- 010-0612-9
    • (2011) Diclofenac on the Zebra Mussel (Dreissena Polymorpha). Water Air Soil Pollut , vol.217 , Issue.589-601 , pp. 0612-0619
    • Parolini, M.1    Binelli, A.2    Provini, A.3
  • 46
    • 79961126621 scopus 로고    scopus 로고
    • Chronic effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha
    • doi: 10.1016/j.ecoenv. 2011.04.025
    • Parolini M, Binelli A, Provini A (2011b) Chronic effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha. Ecotoxicol Environ Saf 74 (6): 1586-1594. doi: 10.1016/j.ecoenv. 2011.04.025
    • (2011) Ecotoxicol Environ Saf , vol.74 , Issue.6 , pp. 1586-1594
    • Parolini, M.1    Binelli, A.2    Provini, A.3
  • 47
    • 0037400619 scopus 로고    scopus 로고
    • Do pharmaceuticals affect freshwater invertebrates? A study with the cnidarian Hydra vulgaris
    • doi: 10.1016/S0045-6535
    • Pascoe D, Karntanut W, Muller CT (2003) Do pharmaceuticals affect freshwater invertebrates? A study with the cnidarian Hydra vulgaris. Chemosphere 51: 521-528. doi: 10.1016/S0045-6535 (02)00860-3
    • (2003) Chemosphere 51 , vol.521-528 , Issue.2 , pp. 00860-00863
    • Pascoe, D.1    Karntanut, W.2    Muller, C.T.3
  • 48
    • 0343314888 scopus 로고    scopus 로고
    • Detection of micronuclei in haemocytes of zebra mussel and ramshorn snail exposed to pentachlorophenol
    • doi: 10.1016/S1383-5718
    • Pavlica M, Klobucar GIV, Vetma N, Erben R, Papes D (2000) Detection of micronuclei in haemocytes of zebra mussel and ramshorn snail exposed to pentachlorophenol. Mutat Res 465: 145-150. doi: 10.1016/S1383-5718 (99)00222-3
    • (2000) Mutat Res 465 , vol.145-150 , Issue.99 , pp. 00222-00223
    • Pavlica, M.1    Giv, K.2    Vetma, N.3    Erben, R.4    Papes, D.5
  • 49
    • 0031942274 scopus 로고    scopus 로고
    • Lysosomal and antioxidant responses to metals in the antarctic scallop adamussium colbecki
    • doi: 10.1016/S0166-445X (97)00059-3
    • Regoli F, Nigro M, Orlando E (1998) Lysosomal and antioxidant responses to metals in the Antarctic scallop Adamussium colbecki. Aquat Toxicol 40: 375-392. doi: 10.1016/S0166-445X (97)00059-3
    • (1998) Aquat Toxicol , vol.40 , pp. 375-392
    • Regoli, F.1    Nigro, M.2    Orlando, E.3
  • 50
    • 0036745052 scopus 로고    scopus 로고
    • Application of biomarkers for assessing the biological impact of dredged materials in the Mediterranean: The relationship between antioxidant responses and susceptibility to oxidative stress in the red mullet (Mullus barbatus)
    • doi: 10.1016/S0025- 326X
    • Regoli F, Pellegrini D, Winston GW, Gorbi S, Giuliani S, Virno- Lamberti C, Bompadre S (2002) Application of biomarkers for assessing the biological impact of dredged materials in the Mediterranean: the relationship between antioxidant responses and susceptibility to oxidative stress in the red mullet (Mullus barbatus). Mar Pollut Bull 44: 912-922. doi: 10.1016/S0025- 326X (02)00120-0
    • (2002) Mar Pollut Bull 44 , vol.912-922 , Issue.2 , pp. 00120-121
    • Regoli, F.1    Pellegrini, D.2    Winston, G.W.3    Gorbi, S.4    Giuliani, S.5    Virno- Lamberti, C.6    Bompadre, S.7
  • 51
    • 0242319037 scopus 로고    scopus 로고
    • Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and DNA damage in the European eel Anguilla anguilla
    • doi: 10.1897/02-378
    • Regoli F, Winston GW, Gorbi S, Frenzilli G, Nigro M, Corsi I, Focardi S (2003) Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and DNA damage in the European eel Anguilla anguilla. Environ Toxicol Chem 22: 2120-2129. doi: 10.1897/02-378
    • (2003) Environ Toxicol Chem , vol.22 , pp. 2120-2129
    • Regoli, F.1    Winston, G.W.2    Gorbi, S.3    Frenzilli, G.4    Nigro, M.5    Corsi, I.6    Focardi, S.7
  • 52
    • 37349046678 scopus 로고    scopus 로고
    • Evaluation of DNA damages induced by BDE-209 in haemocytes of Dreissena polymorpha using SCGE assay and MN test
    • doi: 10.1002/em.20353
    • Riva C, Binelli A, Cogni D, Provini A (2007) Evaluation of DNA damages induced by BDE-209 in haemocytes of Dreissena polymorpha using SCGE assay and MN test. Environ Mol Mutagen 48: 735-743. doi: 10.1002/em.20353
    • (2007) Environ Mol Mutagen , vol.48 , pp. 735-743
    • Riva, C.1    Binelli, A.2    Cogni, D.3    Provini, A.4
  • 53
    • 72049110796 scopus 로고    scopus 로고
    • Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment
    • doi: 10.1016/j.jhazmat.2009. 10.100
    • Santos LHMLM, Araujo AN, Fachini A, Pena A, Deleure-Matos C, Montenegro MCBSM (2010) Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J Hazard Mat 175 (1-3a): 45-95. doi: 10.1016/j.jhazmat.2009. 10.100
    • (2010) J Hazard Mat 175 (1-3a , pp. 45-95
    • Lhmlm, S.1    Araujo, A.N.2    Fachini, A.3    Pena, A.4    Deleure-Matos, C.5    McBsm, M.6
  • 54
    • 0030992926 scopus 로고    scopus 로고
    • Cytochrome P4502C11 is a target of diclofenac covalent binding in rats
    • doi: 10.1021/tx960167z
    • Shen S, Hargus SJ, Martin BM, Pohl LR (1997) Cytochrome P4502C11 is a target of diclofenac covalent binding in rats. Chem Res Toxicol 10: 420-423. doi: 10.1021/tx960167z
    • (1997) Chem Res Toxicol , vol.10 , pp. 420-423
    • Shen, S.1    Hargus, S.J.2    Martin, B.M.3    Pohl, L.R.4
  • 55
    • 0034630349 scopus 로고    scopus 로고
    • A simple method for accurate estimation of apoptotic cells
    • doi: 10.1006/excr. 2000.4810
    • Singh NP (2000) A simple method for accurate estimation of apoptotic cells. Exp Cell Res 256: 328-337. doi: 10.1006/excr. 2000.4810
    • (2000) Exp Cell Res , vol.256 , pp. 328-337
    • Singh, N.P.1
  • 56
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider E (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 175: 184-191
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.4
  • 57
    • 0141672273 scopus 로고    scopus 로고
    • Exposure, time-dependent DNA strand breakage in hepatopancreas of green-lipped mussels (Perna viridis) exposed to Aroclor, 1254 and mixtures of B[a]P and Aroclor 1254
    • doi: 10.1016/S0025-326X
    • Siu WHL, Hung CLH, Wong HL, Richardson BJ, Lam PKS (2003) Exposure, time-dependent DNA strand breakage in hepatopancreas of green-lipped mussels (Perna viridis) exposed to Aroclor, 1254 and mixtures of B[a]P and Aroclor 1254. Mar Pollut Bull 46: 1285-1293. doi: 10.1016/S0025-326X (03)00234-0
    • (2003) Mar Pollut Bull 46 , vol.1285-1293 , Issue.3 , pp. 00234-235
    • Whl, S.1    Clh, H.2    Wong, H.L.3    Richardson, B.J.4    Pks, L.5
  • 59
    • 0033963058 scopus 로고    scopus 로고
    • Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use
    • doi: 10.1016/S0045-6535 (99
    • Stuer-Lauridsen F, Birkved M, Hansen LP, Holten Lutzhoft HC, Halling-Sorensen B (2000) Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use. Chemosphere 40 (7): 783-793. doi: 10.1016/S0045-6535 (99) 00453-1
    • (2000) Chemosphere 40 , vol.7 , Issue.783-793 , pp. 00453-461
    • Stuer-Lauridsen, F.1    Birkved, M.2    Hansen, L.P.3    Holten Lutzhoft, H.C.4    Halling-Sorensen, B.5
  • 60
    • 0023976547 scopus 로고
    • Diclofenac sodium, a reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
    • Todd PA, Sorkin EM (1988) Diclofenac sodium, a reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 35: 244-285
    • (1988) Drugs , vol.35 , pp. 244-285
    • Todd, P.A.1    Sorkin, E.M.2
  • 61
    • 33646791891 scopus 로고    scopus 로고
    • Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants
    • doi: 10.1016/j.ecoenv.2005.03.013
    • Valavanidis A, Vlahogianni T, Dassenakis M, Scoullos M (2006) Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants. Ecotoxicol Environ Saf 64: 178-189. doi: 10.1016/j.ecoenv.2005.03.013
    • (2006) Ecotoxicol Environ Saf , vol.64 , pp. 178-189
    • Valavanidis, A.1    Vlahogianni, T.2    Dassenakis, M.3    Scoullos, M.4
  • 62
    • 0030851297 scopus 로고    scopus 로고
    • Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: Genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide
    • Van Goethem F, Lison D, Kirsh-Volders M (1997) Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat Res 392: 31-43
    • (1997) Mutat Res , vol.392 , pp. 31-43
    • Van Goethem, F.1    Lison, D.2    Kirsh-Volders, M.3
  • 63
    • 0025905984 scopus 로고
    • Prooxidant and antioxidant mechanism in aquatic organism
    • doi: 10.1016/0166-445X
    • Winston GW, Di Giulio RT (1991) Prooxidant and antioxidant mechanism in aquatic organism. Aquat Toxicol 19: 137-161. doi: 10.1016/0166-445X (91)90033-6
    • (1991) Aquat Toxicol 19 , vol.137-161 , Issue.91 , pp. 90033-90036
    • Winston, G.W.1    Di Giulio, R.T.2
  • 64
    • 0029983030 scopus 로고    scopus 로고
    • Production of reactive oxygen species (ROS) by hemocytes from the marine mussel, Mytilus edulis
    • doi: 10.1016/0742-8413 (95)02091-8
    • Winston GW, Moore MN, Kirchin MA, Soverchia C (1996) Production of reactive oxygen species (ROS) by hemocytes from the marine mussel, Mytilus edulis. Comp Biochem Physiol C 113: 221-229. doi: 10.1016/0742-8413 (95)02091-8
    • (1996) Comp Biochem Physiol C , vol.113 , pp. 221-229
    • Winston, G.W.1    Moore, M.N.2    Kirchin, M.A.3    Soverchia, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.