Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: In vivo evidence for effects on the glutamate system

European Archives of Psychiatry and Clinical Neuroscience

Volumn 262, Issue 1, 2012, Pages 23-31

  Gruber, Oliver ^a   Hasan, Alkomiet ^a   Scherk, Harald ^a   Wobrock, Thomas ^a   Schneider Axmann, Thomas ^a   Ekawardhani, Savira ^c   Schmitt, Andrea ^a   Backens, Martin ^b   Reith, Wolfgang ^b   Meyer, Jobst ^c   Falkai, Peter ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF TRIER   (Germany)

Author keywords

Bipolar disorder; Genetics; Glutamate; Hippocampal plasticity; Magnetic resonance spectroscopy; Neuroimaging; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMIC ACID; N ACETYLASPARTIC ACID; ASPARTIC ACID; CREATINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; METHIONINE; N-ACETYLASPARTATE; PROTON; VALINE;

ADULT; ARTICLE; BIPOLAR I DISORDER; BRAIN FUNCTION; BRAIN REGION; BRAIN SIZE; CAUCASIAN; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HIPPOCAMPUS; HOMOZYGOTE; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHIZOPHRENIA; VERBAL MEMORY; BIPOLAR DISORDER; GENETIC ASSOCIATION; GENETICS; LEARNING; MEMORY; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASPARTIC ACID; BIPOLAR DISORDER; BRAIN-DERIVED NEUROTROPHIC FACTOR; CREATINE; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMORY; METHIONINE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTONS; SCHIZOPHRENIA; VALINE; VERBAL LEARNING;

EID: 84861669640     PISSN: 09401334     EISSN: 14338491     Source Type: Journal    
DOI: 10.1007/s00406-011-0214-6     Document Type: Article

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