Eosinophil granular proteins damage bronchial epithelial cells infected with respiratory syncytial virus

International Archives of Allergy and Immunology

Volumn 158, Issue SUPPL. 1, 2012, Pages 11-18

  Kato, Masahiko ^a   Ishioka, Taisei ^b   Kita, Hirohito ^d   Kozawa, Kunihisa ^b   Hayashi, Yasuhide ^a   Kimura, Hirokazu ^c  

^a Gumna Children S Medical Center   (Japan)

^b GUNMA PREFECTURAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENTAL SCIENCES   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d MAYO CLINIC   (United States)

Author keywords

Eosinophil peroxidase; Major basic protein; Respiratory syncytial virus

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; EOSINOPHIL GRANULE PROTEIN; EOSINOPHIL PEROXIDASE; EOSINOPHIL PROTEIN X; MAJOR BASIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRYPAN BLUE;

APOPTOSIS; ASTHMA; BRONCHUS MUCOSA; CELL DAMAGE; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CYTOTOXICITY; EOSINOPHIL; HUMAN; HUMAN CELL; MICROSCOPY; NECROSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RESPIRATORY SYNCYTIAL VIRUS INFECTION;

BRONCHI; CELL LINE, TUMOR; CELL SURVIVAL; EOSINOPHIL GRANULE PROTEINS; EPITHELIAL CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; STAT3 TRANSCRIPTION FACTOR;

EID: 84861651946     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000337752     Document Type: Conference Paper

References (39)

1. Lemanske RF: Viral infections and asthma inception. J Allergy Clin Immunol 2004; 114: 1023-1026.
2. Black CP: Systematic review of the biology and medical management of respiratory syn-cytial virus infection. Respir Care 2003; 48: 209-233.
3. Gleich GJ: Mechanisms of eosinophil-asso-ciated inflammation. J Allergy Clin Immunol 2000; 105:651-663.
4. Kato M, Abraham RT, Kita H: Tyrosine phosphorylation is required for eosinophil degranulation induced by immobilized im-munoglobulins. J Immunol 1995; 155:357-366.
5. Horie S, Gleich GJ, Kita H: Cytokines directly induce degranulation and superoxide production from human eosinophils. J Allergy Clin Immunol 1996; 98:371-381. (Pubitemid 26326131)
6. Fujiu T, Kato M, Kimura H, Tachibana A, Suzuki M, Nako Y, Morikawa A: Cellular adhesion is required for effector functions of human eosinophils via G-protein coupled receptors. Ann Allergy Asthma Immunol 2002; 89:90-98. (Pubitemid 36188074)
7. Takizawa T, Kato M, Kimura H, Suzuki M, Tachibana A, Obinata H, Izumi T, Tokuyama K, Morikawa A: In h ibition of protei n k inases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor. J Allergy Clin Immunol 2002; 110: 241-248.
8. Ayars GH, Altman LC, Gleich GJ, Loegering DA, Baker CB: Eosinophil-and eosinophil granule-mediated pneumocyte injury. J Al-lerg y Clin Immunol 1985; 76: 595-604. (Pubitemid 15245025)
9. Motojima S, Frigas E, Loegering DA, Gleich GJ: Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am Rev Respir Dis 1989; 139: 801-805. (Pubitemid 19084409)
10. O'Donnell MC, Ackerman SJ, Gleich GJ, Thomas LL: Activation of basophil and mast cell histamine release by eosinophil granule major basic protein. J Exp Med 1983; 157: 1981-1991. (Pubitemid 13060897)
11. Shenoy NG, Gleich GJ, Thomas LL: Eosinophil major basic protein stimulates neutrophil superoxide production by a class IA phosphoinositide 3-kinase and protein kinase C-dependent pathway. J Immunol 2003; 171: 3734-3741. (Pubitemid 37254578)
12. Rohrbach MS, Wheatley CL, Slifman NR, Gleich GJ: Activation of platelets by eosinophil granule proteins. J Exp Med 1990; 172: 1271-1274. (Pubitemid 20343230)
13. Kita H, Abu-Ghazaleh RI, Sur S, Gleich GJ: Eosinophil major basic protein induces de-granulation and IL-8 production by human eosinophils. J Immunol 1995; 154:4749-4758.
14. Ayars GH, Altman LC, McManus MM, Agosti JM, Baker C, Luchtel DL, Loegering DA, Gleich GJ: Injurious effect of the eosinophil peroxide-hydrogen peroxide-halide system and major basic protein on human nasal epithelium in vitro. Am Rev Respir Dis 1989; 140:125-131. (Pubitemid 19177092)
15. Frigas E, Loegering DA, Solley GO, Farrow GM, Gleich GJ: Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayo Clin Proc 1981; 56: 345-353. (Pubitemid 11093805)
16. Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB: Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Respir Dis 1988; 137: 62-69. (Pubitemid 18032827)
17. Frigas E, Motojima S, Gleich GJ: The eosinophilic injury to the mucosa of the airways in the pathogenesis of bronchial asthma. Eur Respir J Suppl 1991; 13: 123s-135s.
18. Erpenbeck VJ, Hohlfeld JM, Petschallies J, Ek lu nd E, Peterson CG, Fabel H, Krug N: L o-cal release of eosinophil peroxidase following segmental allergen provocation in asthma. Clin Exp Allergy 2003; 33:331-336. (Pubitemid 36315174)
19. Filley WV, Holley KE, Kephart GM, Gleich GJ: Identification by immunof luorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet 1982; 2: 11-16. (Pubitemid 12124112)
20. Leiferman KM, Fujisawa T, Gray BH, Gleich GJ: Extracellular deposition of eosinophil and neutrophil granule proteins in the IgE-mediated cutaneous late phase reaction. Lab Invest 1990; 62: 579-589. (Pubitemid 20186359)
21. Kim CK, Kim SW, Park CS, Kim BI, Kang H, Koh YY: Bronchoalveolar lavage cytokine profiles in acute asthma and acute bronchi-olitis. J Allergy Clin Immunol 2003; 112:64-71. (Pubitemid 36819808)
22. Zhao J, Takamura M, Yamaoka A, Odajima Y, Iikura Y: Altered eosinophil levels as a result of viral infection in asthma exacerbation in childhood. Pediatr Allergy Immunol 2002; 13: 47-50. (Pubitemid 34453880)
23. Kristjansson S, Bjarnarson SP, Wennergren G, Palsdottir AH, Arnadottir T, Haraldsson A, Jonsdottir I: Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local Th2-like response. J Allergy Clin Immunol 2005; 116: 805-811. (Pubitemid 41400545)
24. Okamoto N, Ikeda M, Okuda M, Sakamoto T, Takasugi M, Takahashi N, Araki T, Mo-rishima T, Yasui K: Increased eosinophilic cationic protein in nasal f luid in hospitalized wheezy infants with RSV infection. Allergol Int 2011; 60:467-472.
25. Abu-Ghazaleh RI, Dunnette SL, Loegering DA, Checkel JL, Kita H, Thomas LL, Gleich GJ: Eosinophil granule proteins in peripheral blood granulocytes. J Leukoc Biol 1992; 52:611-618. (Pubitemid 23016034)
26. Janakiraman V, Forrest WF, Seshagiri S: Estimation of baculovirus titer based on viable cell size. Nat Protoc 2006; 1:2271-2276.
27. Yamaguchi T, Kimura H, Kurabayashi M, Kozawa K, Kato M: Interferon-7 enhances human eosinophil effector functions induced by granulocyte-macrophage colony-stimulating factor or interleukin-5. Immunol Lett 2008; 118:88-95.
28. Ishioka T, Kimura H, Kita H, Obuchi M, Hoshino H, Noda M, Nishina A, Kozawa K Kato M: Effects of respiratory syncytial virus infection and major basic protein derived from eosinophils in pulmonary alveolar epithelial cells (A549). Cell Biol Int 2011; 35: 467-474.
29. Karin M: Mitogen-activated protein kinase cascades as regulators of stress responses. Ann N Y Acad Sci 1998; 851: 139-146. (Pubitemid 28370374)
30. Kong X, San Juan H, Behera A, Peeples ME, Wu J, Lockey RF, Mohapatra SS: ERK-1/2 activity is required for efficient RSV infection. FEBS Lett 2004; 559:33-38. (Pubitemid 38186699)
31. Singh D, McCann KL, Imani F: MAPK and heat shock protein 27 activation are associated with respiratory syncytial virus induction of human bronchial epithelial monolay-er disruption. Am J Physiol Lung Cell Mol Physiol 2007; 293:L436-L445. (Pubitemid 47205024)
32. Marchant D, Singhera GK, Utokaparch S, Hackett TL, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM, Hegele RG: Toll-like receptor 4-mediated activation of p38 mito-gen-activated protein kinase is a determinant of respiratory virus entry and tropism. J Virol 2010; 84:11359-11373.
33. Levy DE, Darnell JE Jr: STATS: transcrip-tional control and biological impact. Nat Rev Mol Cell Biol 2002; 3:651-662. (Pubitemid 34987786)
34. Liu T, Castro S, Brasier AR, Jamaluddin M, Garofalo R P, Casola A: Reactive oxygen species mediate virus-induced STAT activation: role of tyrosine phosphatases. J Biol Chem 2004; 279: 2461-2469. (Pubitemid 38114229)
35. Kotelkin A, Prikhod'ko EA, Cohen JI, Collins PL, Bukreyev A: Respiratory syncytial virus infection sensitizes cells to apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand. J Virol 2003; 77: 9156-9172. (Pubitemid 37011013)
36. Stewart MJ, Kulkarni SB, Meusel TR, Imani F: c-Jun N-terminal kinase negatively regulates dsRNA and RSV induction of tumor necrosis factor-alpha transcription in human epithelial cells. J Interferon Cytokine Res 2006; 26: 521-533. (Pubitemid 44289895)
37. Takeuchi R, Tsutsumi H, Osaki M, Haseya-ma K, Mizue N, Chiba S: Respiratory syn-cytial virus infection of human alveolar epithelial cells enhances interferon regulatory factor 1 and interleukin-1beta-converting enzyme gene expression but does not cause apoptosis. J Virol 1998; 72:4498-4502. (Pubitemid 28188764)
38. Pifferi M, Ragazzo V, Caramella D, Baldini G: Eosinophil cationic protein in infants with respiratory syncytial virus bronchiol-itis: predictive value for subsequent development of persistent wheezing. Pediatr Pul-monol 2001; 31:419-424. (Pubitemid 32523633)
39. Piippo-Savolainen E, Remes S, Korppi M: Does blood eosinophilia in wheezing infa nts predict later asthma? A prospective 18-20-year follow-up. Allergy Asthma Proc 2007; 28:163-169.