Does blood eosinophilia in wheezing infants predict later asthma? A prospective 18-20-year follow-up

Allergy and Asthma Proceedings

Volumn 28, Issue 2, 2007, Pages 163-169

  Piippo Savolainen, Eija ^a,b   Remes, Sami ^a,b   Korppi, Matti ^a,b  

^a Kuopio University Hospital ^*  (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Adulthood; Asthma; Bronchiolitis; Eosinophils; Infancy; Long term followup; Risk factor

Indexed keywords

ABNORMAL RESPIRATORY SOUND; ADOLESCENT; ADULT; AGE; AGE DISTRIBUTION; ARTICLE; ASTHMA; BLOOD; BRONCHIOLITIS; CHILD; COMPARATIVE STUDY; EOSINOPHILIA; FOLLOW UP; HUMAN; INFANT; LEUKOCYTE COUNT; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; PRESCHOOL CHILD; PROSPECTIVE STUDY; RECURRENT DISEASE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RISK; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL; TIME; VIRAL BRONCHIOLITIS; VIROLOGY;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGE FACTORS; ASTHMA; BRONCHIOLITIS; BRONCHIOLITIS, VIRAL; CHILD; CHILD, PRESCHOOL; EOSINOPHILIA; FOLLOW-UP STUDIES; HUMANS; INFANT; LEUKOCYTE COUNT; LOGISTIC MODELS; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECURRENCE; RESPIRATORY SOUNDS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS;

EID: 34248376884     PISSN: 10885412     EISSN: None     Source Type: Journal    
DOI: 10.2500/app.2007.28.2946     Document Type: Article

References (26)

1. Stein RT, and Martinez FD. Asthma phenotypes in childhood: Lessons for an epidemiological approach. Paediatr Respir Rev 155-161, 2004.
2. Castro-Rodriguez JA, Holberg CJ, Wright AL, et al. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 162:1403-1406, 2000.
3. Koller D, Wojnarowski C, Herkner K, et al. High levels of eosinophil cationic protein in wheezing infants predict the developments of asthma. J Allergy Clin Immunol 6:752-756, 1997.
4. Ehlenfield D, Cameron K, and Welliver R. Eosinophilia at the time of respiratory syncytial virus bronchiolitis predicts childhood reactive airway disease. Pediatrics 105:79-83, 2000.
5. Öyrmar K, Havnen J, Halvorsen T, et al. Eosinophil counts and urinary eosinophil protein X in children hospitalized for wheezing during first year of life: Prediction of recurrent wheezing. Acta Paediatr 90:843-849, 2001.
6. Kotaniemi-Syrjanen A, Vainionpaa R, Reijonen TM, et al. Rhinovirus-induced wheezing in infancy-The first sign of childhood asthma? J Allergy Clin Immunol 111:66-71, 2003.
7. Martinez FD, Stern DA, Wright AL, et al. Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma. J Allergy Clin Immunol 102:915-920, 1998.
8. Hyvarinen M, Kotaniemi-Syrjanen A, Reijonen T, et al. Teenage asthma after severe early childhood wheezing: An 11-year prospective follow-up. Pediatr Pulmonol 40:316-323, 2005.
9. Karakoc F, Remes S, Martinez F, et al. The association between persistent eosinophilia and asthma in childhood in independent of atopic status. Clin Exp Allergy 32:51-56, 2002.
10. Korppi M, Reijonen T, Pöysä L, at al. A 2- to 3- year outcome after bronchiolitis. Am J Dis Child 147:628-631, 1993.
11. Kuikka L, Reijonen T, Remes K, et al. Bronchial asthma after early childhood wheezing: A follow-up until 4.5-6 years of age. Acta Paediatr 83:744-748, 1994.
12. Korppi M, Kuikka L, Reijonen T, et al Bronchial asthma and hyperreactivity after early childhood bronchiolitis or pneumonia. An 8-year follow-up study. Arch Pediatr Adolesc Med 148:1079-1084, 1994.
13. Piippo-Savolainen E, Remes S, Kannisto S, at al. Asthma and lung function 20 years after wheezing in infancy. Results from a prospective follow-up study. Arch Pediatr Adolesc Med 158: 1070-1076, 2004.
14. Hyvarinen M, Piippo-Savolainen E, Korhonen K, at al. Asthma at teenage after bronchiolitis or pneumonia in infancy. Acta Paediatr 94:1378-1383, 2005.
15. Korppi M, Halonen P, Kleemola M, et al. Viral findings in children under the age of two years with expiratory difficulties. Acta Paediatr Scand 75:457-464, 1986.
16. Lewis SM, and Dacie JV. Eosinophil counts by a counting chamber method. In Practical Haematology, 5th ed. Edinburgh: Churchill Livingstone, 1975.
17. Eisen AH. Eosinophilia. In Allergic Diseases of Infancy, Childhood, and Adolescence. Bierman CW, and Pearlman DS (Eds). Philadelphia: W.B. Saunders, 761-762, 1980.
18. Saarinen UM, Juntunen K, Kajosaari M, et al. Serum immuno-globulin E in atopic and non-atopic children aged 6 months to 5 years. A follow-up study. Acta Paediatr Scand 71:489-494, 1982.
19. Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life: Relation with lung function, total serum IgE levels, and skin test reactivity to allergens. N Engl J Med 332:133-138, 1995.
20. Piippo-Savolainen E, Remes S, Kannisto S, et al. Early predictors for adult asthma and lung function abnormalities in infants hospitalized for bronchiolitis. A prospective 18-20 year follow-up. Allergy Asthma Proc 27:341-349, 2006.
21. Quanjer PH, Lebowitz MD, Gregg I, at al. Peak expiratory flow: Conclusions and recommendations of a working party of the European Respiratory Society. Eur Respir J 10:2-8, 1997.
22. Borres MP, and Björksten B. Peripheral blood eosinophils and IL-4 in infancy in relation to the appearance of allergic disease during the first 6 years of life. Pediatr Allergy Immunol 15:216-220, 2004.
23. Bass D, Gonaa T, Szejda P, et al. Eosinopenia of acute infection. Production of eosinopenia by chemotactic factors of acute inflammation. J Clin Invest 65:1265-1271, 1980.
24. Arruda LK, Sole D, Baena-Cagnani CE, et al. Risk factors for asthma and atopy. Curr Opin Allergy Clin Immunol 5:153-159, 2005.
25. Gerritsen J, Koeter G, Monchy J, et al. Allergy in subjects with asthma from childhood to adulthood. J Allergy Clin Immunol 1:116-125, 1990.
26. Roorda R, Gerritsen J, van Aalderen W, et al. Skin reactivity and eosinophil count in relation to the outcome of childhood asthma. Eur Respir J 6:509-516, 1993.