Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl)thiazol-2-yl)hydrazine derivatives

European Journal of Medicinal Chemistry

Volumn 53, Issue , 2012, Pages 246-253

  Secci, Daniela ^a   Bizzarri, Bruna ^a   Bolasco, Adriana ^a   Carradori, Simone ^a   D'Ascenzio, Melissa ^a   Rivanera, Daniela ^b   Mari, Emanuela ^a   Polletta, Lucia ^a   Zicari, Alessandra ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Antifungal drugs; Candida spp.; Cytotoxicity; Hantzsch reaction; Hydrazone; Thiazole

Indexed keywords

1 (FURAN 2 YLMETHYLENE) 2 [4 (4 IODOPHENYL)THIAZOL 2 YL]HYDRAZINE; 1 (HEPTAN 2 YLIDENE) 2 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 HYDRAZINE; 1 [1 (FURAN 2 YL)ETHYLIDENE] 2 [4 (4 IODOPHENYL)THIAZOL 2 YL]HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 (2 METHYLCYCLOPENTYLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 (3 METHYLCYCLOPENTYLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 (PENTAN 2 YLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 (PENTAN 3YLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2YL] 2 (2 METHYLCYCLOHEXYLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2YL] 2 (3 METHYLCYCLOHEXYLIDENE)HYDRAZINE; 1 [4 (4 IODOPHENYL)THIAZOL 2YL] 2 (4 METHYLCYCLOHEXYLIDENE)HYDRAZINE; 1 CYCLOHEPTYLIDENE 2 [4 (4 IODOPHENYL)THIAZOL 2 YL]HYDRAZINE; 1 CYCLOHEXYLIDENE 2 [4 (4 IODOPHENYL)THIAZOL 2 YL]HYDRAZINE; 1 CYCLOPENTYLIDENE 2 [4 (4 IODOPHENYL)THIAZOL 2 YL] 2 HYDRAZINE; [4 (4 IODOPHENYL)THIAZOL 2 YL]HYDRAZINE; AROMATIC COMPOUND; CLOTRIMAZOLE; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA KRUSEI; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG SCREENING; DRUG SYNTHESIS; FUNGUS ISOLATION; HUMAN; IN VITRO STUDY; NONHUMAN;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; CANDIDA; CELL SURVIVAL; CHEMISTRY TECHNIQUES, SYNTHETIC; HEP G2 CELLS; HUMANS; HYDRAZINES; MICROBIAL SENSITIVITY TESTS;

EID: 84861626316     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.04.006     Document Type: Article

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