The multidrug resistant modulator HZ08 reverses multidrug resistance via P-glycoprotein inhibition and apoptosis sensitization in human epidermoid carcinoma cell line KBv200

Arzneimittel-Forschung/Drug Research

Volumn 62, Issue 5, 2012, Pages 236-242

  Zhu, Y L ^a   Cen, J ^b   Zhang, Y Y ^a   Feng, Y D ^a   Yang, Y ^a   Li, Y M ^a   Huang, W L ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b HENAN UNIVERSITY   (China)

Author keywords

apoptosis; HZ08; multidrug resistance; P glycoprotein

Indexed keywords

1 (3,4 DIMETHOXYBENZYL) 2 (N' CYANO N' OCTYLGUANINO) 6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLINE; CASPASE 3; DOXORUBICIN; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BAX; PROTEIN BCL 10; PROTEIN BCL 2; UNCLASSIFIED DRUG; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL SURVIVAL; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MULTIDRUG RESISTANCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE;

EID: 84861615970     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1301344     Document Type: Article

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