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Volumn 20, Issue 12, 2012, Pages 3698-3702

5-(5-(6-[11C]methyl-3,6-diazabicyclo[3.2.0]heptan-3-yl)pyridin- 2-yl)-1H-indole as a potential PET radioligand for imaging cerebral α7-nAChR in mice

(8) Gao, Yongjun a Ravert, Hayden T a Valentine, Heather a Scheffel, Ursula a Finley, Paige a Wong, Dean F a Dannals, Robert F a Horti, Andrew G a

a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

7 nAChR; Nicotinic acetylcholine receptors; Positron emission tomography; Radioligand

Indexed keywords

3 (6 CHLORO 3 PYRIDINYL) 3,6 DIAZABICYCLO[3.2.0]HEPTANE 6 CARBOXYLATE TERT BUTYL ESTER; 3 [6 (10H INDOL 5 YL) 3 PYRIDINYL] 3,6 DIAZABICYCLO[3.2.0]HEPTANE; 3 [6 (1H INDOL 5 YL) 3 PYRIDINYL] 6 BOC 3,6 DIAZABICYCLO[3.2.0]HEPTANE; 5 [5 (6 METHYL 3,6 DIAZABICYCLO[3.2.0]HEPTAN 3 YL)PYRIDIN 2 YL] 1H INDOLE C 11; CARBON 11; INDOLE DERIVATIVE; MUSCARINIC RECEPTOR; N (3 QUINUCLIDINYL)FURO[2,3 C]PYRIDINE 5 CARBOXAMIDE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL TISSUE; BIOLISTIC TRANSFORMATION; BLOOD BRAIN BARRIER; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; MALE; METHYLATION; MOUSE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIATION DOSE; RADIOACTIVITY; RADIOASSAY; RADIOCHEMISTRY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BRAIN; INDOLES; LIGANDS; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; QUINUCLIDINES; RADIOPHARMACEUTICALS; RECEPTORS, NICOTINIC;

MUS;

EID: 84861575418 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.04.056 Document Type: Conference Paper

Times cited : (8)

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