Synthesis and evaluation of new imaging agent for central nicotinic acetylcholine receptor α7 subtype

Nuclear Medicine and Biology

Volumn 37, Issue 3, 2010, Pages 347-355

  Ogawa, Mikako ^a   Nishiyama, Shingo ^b   Tsukada, Hideo ^b   Hatano, Kentaro ^c   Fuchigami, Takeshi ^a   Yamaguchi, Hiroshi ^a,c   Matsushima, Yoshitaka ^a   Ito, Kengo ^c   Magata, Yasuhiro ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CENTRAL RESEARCH LABORATORY   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Alpha7 subtype; Imaging agent; Nicotinic acetylcholine receptor; PET

Indexed keywords

2 METHYLAMINO BENZOIC ACID 1 AZA BICYCLO[2.2.2]OCT 3 YL ESTER C 11; BUNGAROTOXIN RECEPTOR; METHYLLYCACONITINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; EVALUATION RESEARCH; EXPERIMENTAL MONKEY; HIPPOCAMPUS; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; MALE; MOLECULAR IMAGING; MOUSE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION; RAT; RECEPTOR BLOCKING; THALAMUS;

AMINOBENZOIC ACIDS; ANIMALS; BRAIN; CARBON ISOTOPES; ISOTOPE LABELING; MACACA MULATTA; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; ORGAN SPECIFICITY; RADIOPHARMACEUTICALS; RATS; RECEPTORS, NICOTINIC; TISSUE DISTRIBUTION;

EID: 77950300485     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.11.007     Document Type: Article

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