Cardiac telocytes - Their junctions and functional implications

Cell and Tissue Research

Volumn 348, Issue 2, 2012, Pages 265-279

  Gherghiceanu, Mihaela ^a   Popescu, Laurentiu M ^a  

^a VICTOR BABES NATIONAL INSTITUTE OF PATHOLOGY   (Romania)

Author keywords

Cardiomyocytes; Fibroblasts; Heart regeneration; Schwann cells; Stem cells; Telocytes

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL JUNCTION; CELL TYPE; CYTOLOGY; ELECTRON MICROSCOPY; ELECTRON TOMOGRAPHY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FIBROBLAST; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIUM; MACROMOLECULE; MACROPHAGE; MAST CELL; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; SCHWANN CELL; SIGNAL TRANSDUCTION; STEM CELL; STROMA; STRUCTURE ANALYSIS; SYNAPSE; TELOCYTE; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM;

ANIMALS; FIBROBLASTS; HEART; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; MYOCARDIUM; MYOCYTES, CARDIAC; SCHWANN CELLS; STEM CELLS;

EID: 84861551712     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-012-1333-8     Document Type: Article

References (69)

1. Ardeleanu C, Bussolati G (2011) Telocytes are the common cell of origin of both PEComas and GISTs: an evidence-supported hypothesis. J Cell Mol Med 15:2569-2574
2. Ausoni S, Sartore S (2009) The cardiovascular unit as a dynamic player in disease and regeneration. Trends Mol Med 15:543552
3. Bani D, Formigli L, Gherghiceanu M, Faussone-Pellegrini MS (2010) Telocytes as supporting cells for myocardial tissue organization in developing and adult heart. J Cell Mol Med 14:2531-2538
4. Barile L, Lionetti V (2012) Prometheus's Heart: what lies beneath. J Cell Mol Med 16:228-236
5. Barth M, Schumacher H, Kuhn C, Akhyari P, Lichtenberg A, Franke WW (2009) Cordial connections: molecular ensembles and structures of adhering junctions connecting interstitial cells of cardiac valves in situ and in cell culture. Cell Tissue Res 337:63-77
6. Cavey M, Lecuit T (2009) Molecular bases of cell-cell junctions stability and dynamics. Cold Spring Harb Perspect Biol 1: a002998
7. Cismasiu VB, Radu E, Popescu LM (2011) miR-193 expression differentiates telocytes from other stromal cells. J Cell Mol Med 15:1071-1074
8. Cretoiu D, Cretoiu SM, Simionescu AA, Popescu LM (2012) Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum. Histol Histopathol [in press]
9. Driesen RB, Dispersyn GD, Verheyen FK, van den Eijnde SM, Hofstra L, Thone F, Dijkstra P, Debie W, Borgers M, Ramaekers FC (2005) Partial cell fusion: a newly recognized type of communication between dedifferentiating cardiomyocytes and fibroblasts. Cardiovasc Res 68:37-46 (Pubitemid 41253554)
10. Farquhar MG, Palade GE (1963) Junctional complexes in various epithelia. J Cell Biol 17:375-412
11. Faussone-Pellegrini MS, Bani D (2010) Relationships between telocytes and cardiomyocytes during pre- and post-natal life. J Cell Mol Med 14:1061-1063
12. Faussone-Pellegrini MS, Popescu LM (2011) Telocytes. BioMol Concepts 2:481-489
13. Franke WW (2009) Discovering the molecular components of intercellular junctions-a historical view. Cold Spring Harb Perspect Biol 1:a003061
14. Franke WW, Rickelt S, Barth M, Pieperhoff S (2009) The junctions that don't fit the scheme: special symmetrical cell-cell junctions of their own kind. Cell Tissue Res 338:1-17
15. Gherghiceanu M, Popescu LM (2007) Electron microscope tomography: further demonstration of nanocontacts between caveolae and smooth muscle sarcoplasmic reticulum. J Cell Mol Med 11:1416-1418
16. Gherghiceanu M, Popescu LM (2010) Cardiomyocyte precursors and telocytes in epicardial stem cell niche: electron microscope images. J Cell Mol Med 14:871-877
17. Gherghiceanu M, Popescu LM (2011) Heterocellular communication in the heart: electron tomography of telocyte-myocyte junctions. J Cell Mol Med 15:1005-1011
18. Gherghiceanu M, Manole CG, Popescu LM (2010) Telocytes in endocardium: electron microscope evidence. J Cell Mol Med 14:23302334
19. Gherghiceanu M, Barad L, Novak A, Reiter I, Itskovitz-Eldor J, Binah O, Popescu LM (2011) Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure. J Cell Mol Med 15:2539-2551
20. Green KJ, Getsios S, Troyanovsky S, Godsel LM (2010) Intercellular junction assembly, dynamics, and homeostasis. Cold Spring Harb Perspect Biol 2:a000125
21. Heberlein KR, Straub AC, Isakson BE (2009) The myoendothelial junction: breaking through the matrix? Microcirculation 16:307322
22. Hinescu ME, Gherghiceanu M, Suciu L, Popescu LM (2011) Telocytes in pleura: two- and three-dimensional imaging by transmission electron microscopy. Cell Tissue Res 343:389-397
23. Hurtig J, Chiu DT, Onfelt B (2010) Intercellular nanotubes: insights from imaging studies and beyond. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:260-276
24. Jones DL, Wagers AJ (2008) No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol 9:11-21
25. Kakkar R, Lee RT (2010) Intramyocardial fibroblast myocyte communication. Circ Res 106:47-57
26. Kohl P, Camelliti P (2011) Fibroblast-myocyte connections in the heart. Heart Rhythm [Epub ahead of print]. doi: 10.1016/j.hrthm.2011.10.002
27. Kostin S (2010) Myocardial telocytes: a specific new cellular entity. J Cell Mol Med 14:1917-1921
28. Kostin S (2011) Types of cardiomyocyte death and clinical outcomes in patients with heart failure. J Am Coll Cardiol 57:1532-1534
29. Laflamme MA, Murry CE (2011) Heart regeneration. Nature 473:326-335
30. Lampe PD, Lau AF (2004) The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol 36:11711186
31. Lee TH, D'Asti E, Magnus N, Al-Nedawi K, Meehan B, Rak J (2011) Microvesicles as mediators of intercellular communication in cancer-the emerging science of cellular 'debris'. Semin Immuno- pathol 33:455-467
32. Li J, Radice GL (2010) A new perspective on intercalated disc organization: implications for heart disease. Dermatol Res Pract 2010:207835
33. Li TS, Cheng K, Lee ST, Matsushita S, Davis D, Malliaras K, Zhang Y, Matsushita N, Smith RR, Marban E (2010) Cardio- spheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair. Stem Cells 28:2088-2098
34. Li J, Swope D, Raess N, Cheng L, Muller EJ, Radice GL (2011) Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol 31:1134-1144
35. Liehn EA, Postea O, Curaj A, Marx N (2011) Repair after myocardial infarction, between fantasy and reality the role of chemokines. J Am Coll Cardiol 58:2357-2362
36. Limana F, Capogrossi MC, Germani A (2011) The epicardium in cardiac repair: from the stem cell view. Pharmacol Ther 129:82-96
37. Lionetti V (2011) How resident stem cells communicate with cardiac cells in beating heart? J Stem Cell Res Ther 1:e104. doi:10.4172/2157-7633.1000e104
38. Liu JJ, Shen XT, Zheng X, Li Z, Wang J, Qi XF, Cai DQ (2011) Distribution of telocytes in the rat heart. J Clin Rehabil Tiss Eng Res 15:3546-3548
39. Mandache E, Popescu LM, Gherghiceanu M (2007) Myocardial interstitial Cajal-like cells (ICLC) and their nanostructural relationships with intercalated discs: shed vesicles as intermediates. J Cell Mol Med 11:1175-1184 (Pubitemid 350037058)
40. Mandache E, Gherghiceanu M, Macarie C, Kostin S, Popescu LM (2010) Telocytes in human isolated atrial amyloidosis: ultrastruc- tural remodelling. J Cell Mol Med 14:2739-2747
41. Manole CG, Cismaşiu V, Gherghiceanu M, Popescu LM (2011) Experimental acute myocardial infarction: telocytes involvement in neo-angiogenesis. J Cell Mol Med 15:2284-2296
42. Nicolescu MI, Popescu LM (2012) Telocytes in the interstitium of human exocrine pancreas: ultrastructural evidence. Pancreas. doi:10.1097/MPA. 0b013e31823fbded
43. Nicolescu MI, Bucur A, Dinca O, Rusu MC, Popescu LM (2012) Telocytes in parotid glands. Anat Rec 295:378-385
44. Palatinus JA, Rhett JM, Gourdie RG (2010) Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium. J Mol Cell Cardiol 48:550-557
45. Parrinello S, Napoli I, Ribeiro S, Digby PW, Fedorova M, Parkinson DB, Doddrell RD, Nakayama M, Adams RH, Lloyd AC (2010) EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting. Cell 143:145-155
46. Pieperhoff S, Barth M, Rickelt S, Franke WW (2010) Desmosomal molecules in and out of adhering junctions: normal and diseased States of epidermal, cardiac and mesenchymally derived cells. Dermatol Res Pract 2010:139167
47. Popescu LM (2011) The tandem: telocytes-stem cells. Int J Biol Biomed Eng 5:83-92
48. Popescu LM, Faussone-Pellegrini MS (2010) TELOCYTES - a case of serendipity: the winding way from interstitial cells of cajal (ICC), via interstitial cajal-like cells (ICLC) to telocytes. J Cell Mol Med 14:729-740
49. Popescu LM, Gherghiceanu M, Cretoiu D, Radu E (2005) The connective connection: interstitial cells of Cajal (ICC) and ICClike cells establish synapses with immunoreactive cells. Electron microscope study in situ. J Cell Mol Med 9:714-730 (Pubitemid 44151959)
50. Popescu LM, Gherghiceanu M, Manole CG, Faussone-Pellegrini MS (2009) Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches. J Cell Mol Med 13:866-886
51. Popescu LM, Manole CG, Gherghiceanu M, Ardelean A, Nicolescu MI, Hinescu ME, Kostin S (2010) Telocytes in human epicardium. J Cell Mol Med 14:2085-2093
52. Popescu LM, Gherghiceanu M, Kostin S, Faussone-Pellegrini MS (2011a) Telocytes and heart renewing. In: Wang P, Kuo CH, Takeda N, Singal PK (eds) Adaptation biology and medicine, vol 6, Cell adaptations and challenges. Narosa, New Delhi, pp 17-39
53. Popescu LM, Gherghiceanu M, Suciu LC, Manole CG, Hinescu ME (2011b) Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy. Cell Tissue Res 345:391-403
54. Raju H, Alberg C, Sagoo GS, Burton H, Behr ER (2011) Inherited cardiomyopathies. BMJ. doi:10.1136/bmj.d6966
55. Ramachandran S, Palanisamy V (2011) Horizontal transfer of RNAs: exosomes as mediators of intercellular communication. Wiley Interdiscip Rev RNA [Epub ahead of print]. doi:10.1002/wrna.115
56. Rupp H, Rupp TP, Alter P, Jung N, Pankuweit S, Maisch B (2010) Intrapericardial procedures for cardiac regeneration by stem cells: need for minimal invasive access (AttachLifter) to the normal pericardial cavity. Herz 35:458-465
57. Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW (2011) A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res 108:51-59
58. Rusu MC, Jianu AM, Mirancea N, Didilescu AC, Manoiu VS, Paduraru D (2011) Tracheal telocytes [Epub ahead of print]. J Cell Mol Med. doi:10.1111/j.1582- 4934.2011.01465.x
59. Rusu MC, Pop F, Hostiuc S, Curca GC, Jianu AM, Paduraru D (2012) Telocytes form networks in normal cardiac tissues. Histol Histopathol [in press]
60. Sassoli C, Pini A, Mazzanti B, Quercioli F, Nistri S, Saccardi R, Zecchi-Orlandini S, Bani D, Formigli L (2011) Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged-1 signaling and paracrine mechanisms: clues for cardiac regeneration. J Mol Cell Cardiol 51:399-408
61. Sheikh F, Ross RS, Chen J (2009) Cell-cell connection to cardiac disease. Trends Cardiovasc Med 19:182-190
62. Suciu L, Nicolescu MI, Popescu LM (2010a) Cardiac telocytes: serial dynamic images in cell culture. J Cell Mol Med 14:2687-2692
63. Suciu L, Popescu LM, Gherghiceanu M, Regalia T, Nicolescu MI, Hinescu ME, Faussone-Pellegrini MS (2010b) Telocytes in human term placenta: morphology and phenotype. Cells Tissues Organs 192:325-339
64. Suciu LC, Popescu BO, Kostin S, Popescu LM (2011) PDGFR-β positive telocytes in skeletal muscle interstitium. J Cell Mol Med [Epub ahead of print]. doi:10:1111/j.1582-4934.2011.01505.x
65. Wuchter P, Boda-Heggemann J, Straub BK, Grund C, Kuhn C, Krause U, Seckinger A, Peitsch WK, Spring H, Ho AD, Franke WW (2007) Processus and recessus adhaerentes: giant adherens cell junction systems connect and attract human mesenchymal stem cells. Cell Tissue Res 328:499-514 (Pubitemid 46684504)
66. Xiao J, Liang D, Chen YH (2011) The genetics of atrial fibrillation: from the bench to the bedside. Annu Rev Genomics Hum Genet 12:73-96
67. Zheng Y, Manole CG, Bai C, Wang X (2011) Telocyte morphologies and potential roles in diseases. J Cell Physiol [Epub ahead of print]. doi:10.1002/jcp.23022
68. Zhou B, Pu WT (2011) Epicardial epithelial-to-mesenchymal transition in injured heart. J Cell Mol Med 15:2781-2783
69. Zhou J, Zhang Y, Wen X, Cao J, Li D, Lin Q, Wang H, Liu Z, Duan C, Wu K, Wang C (2010) Telocytes accompanying cardiomyocyte in primary culture: two-and three-dimensional culture environment. J Cell Mol Med 14:2641-2645